BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 19027292)

  • 1. Design, synthesis, and pharmacological and pharmacokinetic evaluation of 3-phenyl-5-pyridyl-1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors.
    Sato T; Ashizawa N; Iwanaga T; Nakamura H; Matsumoto K; Inoue T; Nagata O
    Bioorg Med Chem Lett; 2009 Jan; 19(1):184-7. PubMed ID: 19027292
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected].
    Sato T; Ashizawa N; Matsumoto K; Iwanaga T; Nakamura H; Inoue T; Nagata O
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6225-9. PubMed ID: 19783139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase.
    Matsumoto K; Okamoto K; Ashizawa N; Nishino T
    J Pharmacol Exp Ther; 2011 Jan; 336(1):95-103. PubMed ID: 20952484
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic acid derivatives of potential anti-inflammatory activity.
    Rabea SM; El-Koussi NA; Hassan HY; Aboul-Fadl T
    Arch Pharm (Weinheim); 2006 Jan; 339(1):32-40. PubMed ID: 16411174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of 5-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)benzonitrile derivatives as xanthine oxidase inhibitors.
    Zhang TJ; Li SY; Zhang Y; Wu QX; Meng FH
    Chem Biol Drug Des; 2018 Feb; 91(2):526-533. PubMed ID: 28950055
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs.
    Flentge CA; Randolph JT; Huang PP; Klein LL; Marsh KC; Harlan JE; Kempf DJ
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5444-8. PubMed ID: 19679477
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities.
    Lin R; Connolly PJ; Huang S; Wetter SK; Lu Y; Murray WV; Emanuel SL; Gruninger RH; Fuentes-Pesquera AR; Rugg CA; Middleton SA; Jolliffe LK
    J Med Chem; 2005 Jun; 48(13):4208-11. PubMed ID: 15974571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities.
    Bayrak H; Demirbas A; Karaoglu SA; Demirbas N
    Eur J Med Chem; 2009 Mar; 44(3):1057-66. PubMed ID: 18676062
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase.
    Cogan DA; Aungst R; Breinlinger EC; Fadra T; Goldberg DR; Hao MH; Kroe R; Moss N; Pargellis C; Qian KC; Swinamer AD
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3251-5. PubMed ID: 18462940
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and Biological Evaluation of 5-benzyl-3-pyridyl-1H-1,2,4-triazole Derivatives as Xanthine Oxidase Inhibitors.
    Li SY; Zhang TJ; Wu QX; Olounfeh KM; Zhang Y; Meng FH
    Med Chem; 2020; 16(1):119-127. PubMed ID: 30963981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N₁-arylsulfonyl indole derivatives as 5-HT₆ receptor ligands.
    Nirogi RV; Badange R; Kambhampati R; Chindhe A; Deshpande AD; Tiriveedhi V; Kandikere V; Muddana N; Abraham R; Khagga M
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7431-5. PubMed ID: 23141912
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of novel 2-(indol-5-yl)thiazole derivatives as xanthine oxidase inhibitors.
    Song JU; Choi SP; Kim TH; Jung CK; Lee JY; Jung SH; Kim GT
    Bioorg Med Chem Lett; 2015 Mar; 25(6):1254-8. PubMed ID: 25704891
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activities.
    Bubert C; Woo LW; Sutcliffe OB; Mahon MF; Chander SK; Purohit A; Reed MJ; Potter BV
    ChemMedChem; 2008 Nov; 3(11):1708-30. PubMed ID: 18816537
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors.
    Nepali K; Singh G; Turan A; Agarwal A; Sapra S; Kumar R; Banerjee UC; Verma PK; Satti NK; Gupta MK; Suri OP; Dhar KL
    Bioorg Med Chem; 2011 Mar; 19(6):1950-8. PubMed ID: 21353569
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
    Onda K; Shiraki R; Ogiyama T; Yokoyama K; Momose K; Katayama N; Orita M; Yamaguchi T; Furutani M; Hamada N; Takeuchi M; Okada M; Ohta M; Tsukamoto S
    Bioorg Med Chem; 2008 Dec; 16(23):10001-12. PubMed ID: 18952447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potent CYP19 (aromatase) 1-[(benzofuran-2-yl)(phenylmethyl)pyridine, -imidazole, and -triazole inhibitors: synthesis and biological evaluation.
    Saberi MR; Vinh TK; Yee SW; Griffiths BJ; Evans PJ; Simons C
    J Med Chem; 2006 Feb; 49(3):1016-22. PubMed ID: 16451067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4-Methyl-5-phenyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Zhu Y; Olson SH; Hermanowski-Vosatka A; Mundt S; Shah K; Springer M; Thieringer R; Wright S; Xiao J; Zokian H; Balkovec JM
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3405-11. PubMed ID: 18440811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors.
    Zhang TJ; Zhang Y; Tu S; Wu YH; Zhang ZH; Meng FH
    Eur J Med Chem; 2019 Dec; 183():111717. PubMed ID: 31557611
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and in-vitro antifungal activity of 6-substituted-phenyl-2- {[(4'-substituted phenyl-5'-thioxo)-1,2,4-triazol-3-yl]-methyl}-2,3,4,5-tetrahydropyridazin-3-one derivatives.
    Siddiqui AA; Ahamad SR; Mira MS; Hussain SA; Raish M; Kaur R
    Acta Pol Pharm; 2008; 65(2):223-8. PubMed ID: 18666429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion.
    Fukunari A; Okamoto K; Nishino T; Eger BT; Pai EF; Kamezawa M; Yamada I; Kato N
    J Pharmacol Exp Ther; 2004 Nov; 311(2):519-28. PubMed ID: 15190124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.