BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

478 related articles for article (PubMed ID: 19046572)

  • 1. Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy.
    Bentzinger CF; Romanino K; Cloëtta D; Lin S; Mascarenhas JB; Oliveri F; Xia J; Casanova E; Costa CF; Brink M; Zorzato F; Hall MN; Rüegg MA
    Cell Metab; 2008 Nov; 8(5):411-24. PubMed ID: 19046572
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA; Stevens DM; Thoreen CC; Burds AA; Kalaany NY; Moffat J; Brown M; Fitzgerald KJ; Sabatini DM
    Dev Cell; 2006 Dec; 11(6):859-71. PubMed ID: 17141160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Raptor swoops in on metabolism.
    Shaw RJ
    Cell Metab; 2008 Nov; 8(5):343-4. PubMed ID: 19046565
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.
    Tandelilin AA; Hirase T; Hudoyo AW; Cheng J; Toyama K; Morisaki H; Morisaki T
    BMC Endocr Disord; 2015 Mar; 15():11. PubMed ID: 25887856
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.
    Risson V; Mazelin L; Roceri M; Sanchez H; Moncollin V; Corneloup C; Richard-Bulteau H; Vignaud A; Baas D; Defour A; Freyssenet D; Tanti JF; Le-Marchand-Brustel Y; Ferrier B; Conjard-Duplany A; Romanino K; Bauché S; Hantaï D; Mueller M; Kozma SC; Thomas G; Rüegg MA; Ferry A; Pende M; Bigard X; Koulmann N; Schaeffer L; Gangloff YG
    J Cell Biol; 2009 Dec; 187(6):859-74. PubMed ID: 20008564
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
    Wang S; Amato KR; Song W; Youngblood V; Lee K; Boothby M; Brantley-Sieders DM; Chen J
    Mol Cell Biol; 2015 Apr; 35(7):1299-313. PubMed ID: 25582201
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
    Romanino K; Mazelin L; Albert V; Conjard-Duplany A; Lin S; Bentzinger CF; Handschin C; Puigserver P; Zorzato F; Schaeffer L; Gangloff YG; Rüegg MA
    Proc Natl Acad Sci U S A; 2011 Dec; 108(51):20808-13. PubMed ID: 22143799
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
    Jacinto E; Facchinetti V; Liu D; Soto N; Wei S; Jung SY; Huang Q; Qin J; Su B
    Cell; 2006 Oct; 127(1):125-37. PubMed ID: 16962653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.
    Guridi M; Kupr B; Romanino K; Lin S; Falcetta D; Tintignac L; Rüegg MA
    Skelet Muscle; 2016; 6():13. PubMed ID: 27004103
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy.
    Reyes NL; Banks GB; Tsang M; Margineantu D; Gu H; Djukovic D; Chan J; Torres M; Liggitt HD; Hirenallur-S DK; Hockenbery DM; Raftery D; Iritani BM
    Proc Natl Acad Sci U S A; 2015 Jan; 112(2):424-9. PubMed ID: 25548157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
    Cunningham JT; Rodgers JT; Arlow DH; Vazquez F; Mootha VK; Puigserver P
    Nature; 2007 Nov; 450(7170):736-40. PubMed ID: 18046414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes.
    Kudchodkar SB; Yu Y; Maguire TG; Alwine JC
    Proc Natl Acad Sci U S A; 2006 Sep; 103(38):14182-7. PubMed ID: 16959881
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mTOR phosphorylated at S2448 binds to raptor and rictor.
    Rosner M; Siegel N; Valli A; Fuchs C; Hengstschläger M
    Amino Acids; 2010 Jan; 38(1):223-8. PubMed ID: 19145465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos.
    Zhang Z; Zhang G; Xu X; Su W; Yu B
    Mol Cell Biochem; 2012 Feb; 361(1-2):249-57. PubMed ID: 22057724
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
    Han EK; Leverson JD; McGonigal T; Shah OJ; Woods KW; Hunter T; Giranda VL; Luo Y
    Oncogene; 2007 Aug; 26(38):5655-61. PubMed ID: 17334390
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex.
    Lopez RJ; Mosca B; Treves S; Maj M; Bergamelli L; Calderon JC; Bentzinger CF; Romanino K; Hall MN; Rüegg MA; Delbono O; Caputo C; Zorzato F
    Biochem J; 2015 Feb; 466(1):123-35. PubMed ID: 25431931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
    Shende P; Xu L; Morandi C; Pentassuglia L; Heim P; Lebboukh S; Berthonneche C; Pedrazzini T; Kaufmann BA; Hall MN; Rüegg MA; Brink M
    Cardiovasc Res; 2016 Jan; 109(1):103-14. PubMed ID: 26598511
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3.
    Hua C; Guo H; Bu J; Zhou M; Cheng H; He F; Wang J; Wang X; Zhang Y; Wang Q; Zhou J; Cheng T; Xu M; Yuan W
    Exp Hematol; 2014 Dec; 42(12):1031-40.e1-4. PubMed ID: 25201756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.
    Rosner M; Hengstschläger M
    Hum Mol Genet; 2008 Oct; 17(19):2934-48. PubMed ID: 18614546
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in mice.
    Kogasaka Y; Hoshino Y; Hiradate Y; Tanemura K; Sato E
    Mol Reprod Dev; 2013 Apr; 80(4):334-48. PubMed ID: 23440873
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.