BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 19047164)

  • 1. Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue.
    Leamon CP; Reddy JA; Vetzel M; Dorton R; Westrick E; Parker N; Wang Y; Vlahov I
    Cancer Res; 2008 Dec; 68(23):9839-44. PubMed ID: 19047164
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.
    Reddy JA; Westrick E; Santhapuram HK; Howard SJ; Miller ML; Vetzel M; Vlahov I; Chari RV; Goldmacher VS; Leamon CP
    Cancer Res; 2007 Jul; 67(13):6376-82. PubMed ID: 17616697
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo structural activity and optimization studies of folate-tubulysin conjugates.
    Reddy JA; Dorton R; Dawson A; Vetzel M; Parker N; Nicoson JS; Westrick E; Klein PJ; Wang Y; Vlahov IR; Leamon CP
    Mol Pharm; 2009; 6(5):1518-25. PubMed ID: 19630399
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The therapeutic efficiency of FP-PEA/TAM67 gene complexes via folate receptor-mediated endocytosis in a xenograft mice model.
    Arote RB; Hwang SK; Lim HT; Kim TH; Jere D; Jiang HL; Kim YK; Cho MH; Cho CS
    Biomaterials; 2010 Mar; 31(8):2435-45. PubMed ID: 20022105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improved therapeutic activity of folate-targeted liposomal doxorubicin in folate receptor-expressing tumor models.
    Gabizon A; Tzemach D; Gorin J; Mak L; Amitay Y; Shmeeda H; Zalipsky S
    Cancer Chemother Pharmacol; 2010 May; 66(1):43-52. PubMed ID: 19779718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy.
    Leamon CP; Reddy JA; Vlahov IR; Dorton R; Bloomfield A; Vetzel M; Klein PJ; Westrick E; Xu LC; Wang Y
    Cancer Chemother Pharmacol; 2017 Jun; 79(6):1151-1160. PubMed ID: 28451831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.
    Reddy JA; Dorton R; Westrick E; Dawson A; Smith T; Xu LC; Vetzel M; Kleindl P; Vlahov IR; Leamon CP
    Cancer Res; 2007 May; 67(9):4434-42. PubMed ID: 17483358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of high and low folate diets on tissue folate receptor levels and antitumor responses toward folate-drug conjugates.
    Leamon CP; Reddy JA; Dorton R; Bloomfield A; Emsweller K; Parker N; Westrick E
    J Pharmacol Exp Ther; 2008 Dec; 327(3):918-25. PubMed ID: 18791065
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Folate-targeted dinitrophenyl hapten immunotherapy: effect of linker chemistry on antitumor activity and allergic potential.
    Lu Y; You F; Vlahov I; Westrick E; Fan M; Low PS; Leamon CP
    Mol Pharm; 2007; 4(5):695-706. PubMed ID: 17784727
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isostructural folate conjugates radiolabeled with the matched pair 99mTc/188Re: a potential strategy for diagnosis and therapy of folate receptor-positive tumors.
    Müller C; Schubiger PA; Schibli R
    Nucl Med Biol; 2007 Aug; 34(6):595-601. PubMed ID: 17707798
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative.
    Ross TL; Honer M; Lam PY; Mindt TL; Groehn V; Schibli R; Schubiger PA; Ametamey SM
    Bioconjug Chem; 2008 Dec; 19(12):2462-70. PubMed ID: 19053298
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Folate-targeted chemotherapy.
    Leamon CP; Reddy JA
    Adv Drug Deliv Rev; 2004 Apr; 56(8):1127-41. PubMed ID: 15094211
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate.
    Leamon CP; Reddy JA; Vlahov IR; Kleindl PJ; Vetzel M; Westrick E
    Bioconjug Chem; 2006; 17(5):1226-32. PubMed ID: 16984132
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Folate receptor-mediated antitumor drugs].
    Zhao J; Cao SL; Zheng XL; Zhao B
    Yao Xue Xue Bao; 2009 Feb; 44(2):109-14. PubMed ID: 19408677
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
    Gibbs DD; Theti DS; Wood N; Green M; Raynaud F; Valenti M; Forster MD; Mitchell F; Bavetsias V; Henderson E; Jackman AL
    Cancer Res; 2005 Dec; 65(24):11721-8. PubMed ID: 16357184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic.
    Leamon CP; Reddy JA; Vlahov IR; Vetzel M; Parker N; Nicoson JS; Xu LC; Westrick E
    Bioconjug Chem; 2005; 16(4):803-11. PubMed ID: 16029021
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivo.
    Leamon CP; Cooper SR; Hardee GE
    Bioconjug Chem; 2003; 14(4):738-47. PubMed ID: 12862426
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of (99m)Tc-EC20 in xenografted and syngeneic tumor-bearing mice.
    Müller C; Reddy JA; Leamon CP; Schibli R
    Mol Pharm; 2010 Apr; 7(2):597-604. PubMed ID: 20199053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts.
    Yoshizawa T; Hattori Y; Hakoshima M; Koga K; Maitani Y
    Eur J Pharm Biopharm; 2008 Nov; 70(3):718-25. PubMed ID: 18647651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Folate receptor specific anti-tumor activity of folate-mitomycin conjugates.
    Reddy JA; Westrick E; Vlahov I; Howard SJ; Santhapuram HK; Leamon CP
    Cancer Chemother Pharmacol; 2006 Aug; 58(2):229-36. PubMed ID: 16331500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.