BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 1905153)

  • 1. Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential.
    McGuinness BF; Lipman R; Goldstein J; Nakanishi K; Tomasz M
    Biochemistry; 1991 Jul; 30(26):6444-53. PubMed ID: 1905153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.
    Paz MM; Das A; Palom Y; He QY; Tomasz M
    J Med Chem; 2001 Aug; 44(17):2834-42. PubMed ID: 11495594
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation.
    Maliepaard M; de Mol NJ; Tomasz M; Gargiulo D; Janssen LH; van Duynhoven JP; van Velzen EJ; Verboom W; Reinhoudt DN
    Biochemistry; 1997 Jul; 36(30):9211-20. PubMed ID: 9230054
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of glutathione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione-mitomycin-DNA adduct.
    Sharma M; He QY; Tomasz M
    Chem Res Toxicol; 1994; 7(3):401-7. PubMed ID: 8075372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G; Lipman R; Cummings J; Tomasz M
    Biochemistry; 1997 Nov; 36(46):14128-36. PubMed ID: 9369485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of monofunctional and bifunctional alkylation of DNA by mitomycin C.
    Tomasz M; Chawla AK; Lipman R
    Biochemistry; 1988 May; 27(9):3182-7. PubMed ID: 3134045
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of pH on DNA alkylation by enzyme-activated mitomycin C and porfiromycin.
    Yu F; Pan SS
    Mol Pharmacol; 1993 Jun; 43(6):863-9. PubMed ID: 8391116
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interdependent Sequence Selectivity and Diastereoselectivity in the Alkylation of DNA by Decarbamoylmitomycin C.
    Aguilar W; Paz MM; Vargas A; Zheng M; Cheng SY; Champeil E
    Chemistry; 2018 Sep; 24(50):13278-13289. PubMed ID: 29958326
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts.
    Champeil E; Cheng SY; Huang BT; Conchero-Guisan M; Martinez T; Paz MM; Sapse AM
    Bioorg Chem; 2016 Apr; 65():90-9. PubMed ID: 26894558
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA.
    Tomasz M; Lipman R; Chowdary D; Pawlak J; Verdine GL; Nakanishi K
    Science; 1987 Mar; 235(4793):1204-8. PubMed ID: 3103215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C.
    Palom Y; Suresh Kumar G; Tang LQ; Paz MM; Musser SM; Rockwell S; Tomasz M
    Chem Res Toxicol; 2002 Nov; 15(11):1398-406. PubMed ID: 12437330
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FR900482, a close cousin of mitomycin C that exploits mitosene-based DNA cross-linking.
    Williams RM; Rajski SR; Rollins SB
    Chem Biol; 1997 Feb; 4(2):127-37. PubMed ID: 9190287
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recognition of specific DNA sequences by mitomycin C for alkylation.
    Kumar S; Lipman R; Tomasz M
    Biochemistry; 1992 Feb; 31(5):1399-407. PubMed ID: 1736997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.
    Paz MM; Ladwa S; Champeil E; Liu Y; Rockwell S; Boamah EK; Bargonetti J; Callahan J; Roach J; Tomasz M
    Chem Res Toxicol; 2008 Dec; 21(12):2370-8. PubMed ID: 19053323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins.
    Gargiulo D; Kumar GS; Musser SS; Tomasz M
    Nucleic Acids Symp Ser; 1995; (34):169-70. PubMed ID: 8841606
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA alkylation by enzyme-activated mitomycin C.
    Pan SS; Iracki T; Bachur NR
    Mol Pharmacol; 1986 Jun; 29(6):622-8. PubMed ID: 3086708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective recognition of the m5CpG dinucleotide sequence in DNA by mitomycin C for alkylation and cross-linking.
    Johnson WS; He QY; Tomasz M
    Bioorg Med Chem; 1995 Jun; 3(6):851-60. PubMed ID: 7582961
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitomycin dimers: polyfunctional cross-linkers of DNA.
    Paz MM; Kumar GS; Glover M; Waring MJ; Tomasz M
    J Med Chem; 2004 Jun; 47(12):3308-19. PubMed ID: 15163210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity.
    Paz MM; Das TA; Tomasz M
    Bioorg Med Chem; 1999 Dec; 7(12):2713-26. PubMed ID: 10658576
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Duplex oligodeoxyribonucleotides cross-linked by mitomycin C at a single site: synthesis, properties, and cross-link reversibility.
    Borowy-Borowski H; Lipman R; Chowdary D; Tomasz M
    Biochemistry; 1990 Mar; 29(12):2992-9. PubMed ID: 2110820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.