BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

352 related articles for article (PubMed ID: 19053086)

  • 1. Synthesis and structure-activity relationships of ferrocenyl tamoxifen derivatives with modified side chains.
    Nguyen A; Top S; Pigeon P; Vessières A; Hillard EA; Plamont MA; Huché M; Rigamonti C; Jaouen G
    Chemistry; 2009; 15(3):684-96. PubMed ID: 19053086
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer cell lines.
    Top S; Vessières A; Leclercq G; Quivy J; Tang J; Vaissermann J; Huché M; Jaouen G
    Chemistry; 2003 Nov; 9(21):5223-36. PubMed ID: 14613131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds.
    Zekri O; Hillard EA; Top S; Vessières A; Pigeon P; Plamont MA; Huché M; Boutamine S; McGlinchey MJ; Müller-Bunz H; Jaouen G
    Dalton Trans; 2009 Jun; (22):4318-26. PubMed ID: 19662309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of nonisomerizable derivatives of tamoxifen: importance of hydroxyl group and side chain positioning for biological activity.
    Murphy CS; Parker CJ; McCague R; Jordan VC
    Mol Pharmacol; 1991 Mar; 39(3):421-8. PubMed ID: 2005879
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif.
    Hillard EA; Pigeon P; Vessières A; Amatore C; Jaouen G
    Dalton Trans; 2007 Nov; (43):5073-81. PubMed ID: 17992292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.
    Pigeon P; Top S; Vessières A; Huché M; Hillard EA; Salomon E; Jaouen G
    J Med Chem; 2005 Apr; 48(8):2814-21. PubMed ID: 15828819
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthetic and mechanistic pathways of cis and trans-hydroxytamoxifen drug derivatives reacting with Cp*Rh complexes that involve η1-N, η2-N,O, η1-O, and η6 bonding modes, via a novel N-π rearrangement; relative binding affinities and computer docking studies of cis and trans-η6-Cp*Rh-hydroxytamoxifen complexes at the estrogen, ERα and ERβ receptors, and growth inhibition to breast cancer cells.
    Top S; Efremenko I; Rager MN; Vessières A; Yaswen P; Jaouen G; Fish RH
    Inorg Chem; 2011 Jan; 50(1):271-84. PubMed ID: 21121684
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.
    Liu X; Pisha E; Tonetti DA; Yao D; Li Y; Yao J; Burdette JE; Bolton JL
    Chem Res Toxicol; 2003 Jul; 16(7):832-7. PubMed ID: 12870885
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective estrogen-receptor modulators (SERMs) in the cyclopentadienylrhenium tricarbonyl series: synthesis and biological behaviour.
    Top S; Vessières A; Pigeon P; Rager MN; Huché M; Salomon E; Cabestaing C; Vaissermann J; Jaouen G
    Chembiochem; 2004 Aug; 5(8):1104-13. PubMed ID: 15300835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of basic side chain derivatives of Analog II as pure antiestrogens and antitumor agents.
    Magarian RA; Avor KS; Overacre LB; Kunchandy J; Paxton TR
    Anticancer Drug Des; 1995 Jun; 10(4):311-31. PubMed ID: 7786397
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carboxylic acid analogues of tamoxifen: (Z)-2-[p-(1, 2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine. Estrogen receptor affinity and estrogen antagonist effects in MCF-7 cells.
    Kraft KS; Ruenitz PC; Bartlett MG
    J Med Chem; 1999 Aug; 42(16):3126-33. PubMed ID: 10447957
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro.
    Vessières A; Top S; Pigeon P; Hillard E; Boubeker L; Spera D; Jaouen G
    J Med Chem; 2005 Jun; 48(12):3937-40. PubMed ID: 15943467
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A series of unconjugated ferrocenyl phenols: prospects as anticancer agents.
    Hillard E; Vessières A; Le Bideau F; Plazuk D; Spera D; Huché M; Jaouen G
    ChemMedChem; 2006 May; 1(5):551-9. PubMed ID: 16892391
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genomic action of permanently charged tamoxifen derivatives via estrogen receptor-alpha.
    Rivera-Guevara C; Pérez-Alvarez V; García-Becerra R; Ordaz-Rosado D; Morales-Ríos MS; Hernández-Gallegos E; Cooney AJ; Bravo-Gómez ME; Larrea F; Camacho J
    Bioorg Med Chem; 2010 Aug; 18(15):5593-601. PubMed ID: 20621492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Organometallic cyclic polyphenols derived from 1,2-(alpha-keto tri or tetra methylene) ferrocene show strong antiproliferative activity on hormone-independent breast cancer cells.
    Plazuk D; Top S; Vessières A; Plamont MA; Huché M; Zakrzewski J; Makal A; Woźniak K; Jaouen G
    Dalton Trans; 2010 Aug; 39(32):7444-50. PubMed ID: 20614088
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The presence of a ferrocenyl unit on an estrogenic molecule is not always sufficient to generate in vitro cytotoxicity.
    Vessières A; Spera D; Top S; Misterkiewicz B; Heldt JM; Hillard E; Huché M; Plamont MA; Napolitano E; Fiaschi R; Jaouen G
    ChemMedChem; 2006 Nov; 1(11):1275-81. PubMed ID: 17022106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Guide-lines in the design of new antiestrogens and cytotoxic-linked estrogens for the treatment of breast cancer.
    Leclercq G; Devleeschouwer N; Heuson JC
    J Steroid Biochem; 1983 Jul; 19(1A):75-85. PubMed ID: 6887875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters.
    Minervini F; Giannoccaro A; Cavallini A; Visconti A
    Toxicol Lett; 2005 Dec; 159(3):272-83. PubMed ID: 15994033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reactivity and antiproliferative activity of ferrocenyl-tamoxifen adducts with cyclodextrins against hormone-independent breast-cancer cell lines.
    Buriez O; Heldt JM; Labbé E; Vessières A; Jaouen G; Amatore C
    Chemistry; 2008; 14(27):8195-203. PubMed ID: 18668496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol.
    Tan YL; Pigeon P; Hillard EA; Top S; Plamont MA; Vessières A; McGlinchey MJ; Müller-Bunz H; Jaouen G
    Dalton Trans; 2009 Dec; (48):10871-81. PubMed ID: 20023917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.