These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 19053182)

  • 41. Chemical Reactivity of Emodin and Its Oxidative Metabolites to Thiols.
    Qin B; Xu Y; Chen J; Huang W; Peng Y; Zheng J
    Chem Res Toxicol; 2016 Dec; 29(12):2114-2124. PubMed ID: 27989148
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Comparative metabolism of four limonoids in human liver microsomes using ultra-high-performance liquid chromatography coupled with high-resolution LTQ-Orbitrap mass spectrometry.
    Ren W; Xin SK; Han LY; Zuo R; Li Y; Gong MX; Wei XL; Zhou YY; He J; Wang HJ; Si N; Zhao HY; Yang J; Bian BL
    Rapid Commun Mass Spectrom; 2015 Nov; 29(21):2045-56. PubMed ID: 26443405
    [TBL] [Abstract][Full Text] [Related]  

  • 43. In vitro metabolism of diphenyl diselenide in rat liver fractions. Conjugation with GSH and binding to thiol groups.
    Prigol M; Nogueira CW; Zeni G; Bronze MR; Constantino L
    Chem Biol Interact; 2012 Dec; 200(2-3):65-72. PubMed ID: 23022272
    [TBL] [Abstract][Full Text] [Related]  

  • 44. In vitro metabolism of chlorotriazines: characterization of simazine, atrazine, and propazine metabolism using liver microsomes from rats treated with various cytochrome P450 inducers.
    Hanioka N; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M
    Toxicol Appl Pharmacol; 1999 May; 156(3):195-205. PubMed ID: 10222312
    [TBL] [Abstract][Full Text] [Related]  

  • 45. One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
    Boerma JS; Vermeulen NP; Commandeur JN
    Chem Biol Interact; 2014 Jan; 207():32-40. PubMed ID: 24246759
    [TBL] [Abstract][Full Text] [Related]  

  • 46. In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity.
    Sun Q; Zhu R; Foss FW; Macdonald TL
    Chem Res Toxicol; 2008 Mar; 21(3):711-9. PubMed ID: 18298092
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Oxidative deboronation of the peptide boronic acid proteasome inhibitor bortezomib: contributions from reactive oxygen species in this novel cytochrome P450 reaction.
    Labutti J; Parsons I; Huang R; Miwa G; Gan LS; Daniels JS
    Chem Res Toxicol; 2006 Apr; 19(4):539-46. PubMed ID: 16608165
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases.
    Venkataraman H; den Braver MW; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2014 Dec; 27(12):2071-81. PubMed ID: 25372302
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Metabolism and pharmacokinetics of 3-n-butylphthalide (NBP) in humans: the role of cytochrome P450s and alcohol dehydrogenase in biotransformation.
    Diao X; Deng P; Xie C; Li X; Zhong D; Zhang Y; Chen X
    Drug Metab Dispos; 2013 Feb; 41(2):430-44. PubMed ID: 23169608
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Mechanisms of NSAID-induced hepatotoxicity: focus on nimesulide.
    Boelsterli UA
    Drug Saf; 2002; 25(9):633-48. PubMed ID: 12137558
    [TBL] [Abstract][Full Text] [Related]  

  • 51. In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
    Joshi EM; Heasley BH; Chordia MD; Macdonald TL
    Chem Res Toxicol; 2004 Feb; 17(2):137-43. PubMed ID: 14967000
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Bioactivation of the nontricyclic antidepressant nefazodone to a reactive quinone-imine species in human liver microsomes and recombinant cytochrome P450 3A4.
    Kalgutkar AS; Vaz AD; Lame ME; Henne KR; Soglia J; Zhao SX; Abramov YA; Lombardo F; Collin C; Hendsch ZS; Hop CE
    Drug Metab Dispos; 2005 Feb; 33(2):243-53. PubMed ID: 15523046
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Metabolism of bergamottin by cytochromes P450 2B6 and 3A5.
    Kent UM; Lin HL; Noon KR; Harris DL; Hollenberg PF
    J Pharmacol Exp Ther; 2006 Sep; 318(3):992-1005. PubMed ID: 16785317
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s.
    Wen B; Ma L; Zhu M
    Chem Biol Interact; 2008 May; 173(1):59-67. PubMed ID: 18359012
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Identification of the ortho-benzoquinone intermediate of 5-O-caffeoylquinic acid in vitro and in vivo: comparison of bioactivation under normal and pathological situations.
    Xie C; Zhong D; Chen X
    Drug Metab Dispos; 2012 Aug; 40(8):1628-40. PubMed ID: 22551521
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Characterization of novel dihydrothienopyridinium and thienopyridinium metabolites of ticlopidine in vitro: role of peroxidases, cytochromes p450, and monoamine oxidases.
    Dalvie DK; O'Connell TN
    Drug Metab Dispos; 2004 Jan; 32(1):49-57. PubMed ID: 14709620
    [TBL] [Abstract][Full Text] [Related]  

  • 57. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
    Grillo MP; Ma J; Teffera Y; Waldon DJ
    Drug Metab Dispos; 2008 Sep; 36(9):1740-4. PubMed ID: 18541695
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Effect of human glutathione S-transferases on glutathione-dependent inactivation of cytochrome P450-dependent reactive intermediates of diclofenac.
    Dragovic S; Boerma JS; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2013 Nov; 26(11):1632-41. PubMed ID: 24083800
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Metabolism related toxicity of diclofenac in yeast as model system.
    van Leeuwen JS; Vredenburg G; Dragovic S; Tjong TF; Vos JC; Vermeulen NP
    Toxicol Lett; 2011 Feb; 200(3):162-8. PubMed ID: 21111035
    [TBL] [Abstract][Full Text] [Related]  

  • 60. In vitro metabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s.
    Joo J; Wu Z; Lee B; Shon JC; Lee T; Lee IK; Sim T; Kim KH; Kim ND; Kim SH; Liu KH
    Biopharm Drug Dispos; 2015 Apr; 36(3):163-73. PubMed ID: 25451157
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.