These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 19053823)

  • 1. Novel high-affinity and selective biaromatic 4-substituted gamma-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies.
    Høg S; Wellendorph P; Nielsen B; Frydenvang K; Dahl IF; Bräuner-Osborne H; Brehm L; Frølund B; Clausen RP
    J Med Chem; 2008 Dec; 51(24):8088-95. PubMed ID: 19053823
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites.
    Wellendorph P; Høg S; Sabbatini P; Pedersen MH; Martiny L; Knudsen GM; Frølund B; Clausen RP; Bräuner-Osborne H
    J Pharmacol Exp Ther; 2010 Nov; 335(2):458-64. PubMed ID: 20696866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel cyclic gamma-hydroxybutyrate (GHB) analogs with high affinity and stereoselectivity of binding to GHB sites in rat brain.
    Wellendorph P; Høg S; Greenwood JR; de Lichtenberg A; Nielsen B; Frølund B; Brehm L; Clausen RP; Bräuner-Osborne H
    J Pharmacol Exp Ther; 2005 Oct; 315(1):346-51. PubMed ID: 16014570
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phenylacetic acids and the structurally related non-steroidal anti-inflammatory drug diclofenac bind to specific gamma-hydroxybutyric acid sites in rat brain.
    Wellendorph P; Høg S; Skonberg C; Bräuner-Osborne H
    Fundam Clin Pharmacol; 2009 Apr; 23(2):207-13. PubMed ID: 19645815
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A tertiary alcohol analog of gamma-hydroxybutyric acid as a specific gamma-hydroxybutyric acid receptor ligand.
    Wu H; Zink N; Carter LP; Mehta AK; Hernandez RJ; Ticku MK; Lamb R; France CP; Coop A
    J Pharmacol Exp Ther; 2003 May; 305(2):675-9. PubMed ID: 12606613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GHB receptor targets in the CNS: focus on high-affinity binding sites.
    Bay T; Eghorn LF; Klein AB; Wellendorph P
    Biochem Pharmacol; 2014 Jan; 87(2):220-8. PubMed ID: 24269284
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB receptor (GABABR) binding sites are distinctive from one another: molecular evidence.
    Wu Y; Ali S; Ahmadian G; Liu CC; Wang YT; Gibson KM; Calver AR; Francis J; Pangalos MN; Carter Snead O
    Neuropharmacology; 2004 Dec; 47(8):1146-56. PubMed ID: 15567424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and in vitro pharmacology of new radiolabeled gamma-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity gamma-hydroxybutyric acid binding sites.
    Sabbatini P; Wellendorph P; Høg S; Pedersen MH; Bräuner-Osborne H; Martiny L; Frølund B; Clausen RP
    J Med Chem; 2010 Sep; 53(17):6506-10. PubMed ID: 20715819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization and pharmacology of the GHB receptor.
    Ticku MK; Mehta AK
    Ann N Y Acad Sci; 2008 Oct; 1139():374-85. PubMed ID: 18991884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding characteristics of the gamma-hydroxybutyric acid receptor antagonist [(3)H](2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid in the rat brain.
    Mehta AK; Muschaweck NM; Maeda DY; Coop A; Ticku MK
    J Pharmacol Exp Ther; 2001 Dec; 299(3):1148-53. PubMed ID: 11714906
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.
    Kaupmann K; Cryan JF; Wellendorph P; Mombereau C; Sansig G; Klebs K; Schmutz M; Froestl W; van der Putten H; Mosbacher J; Bräuner-Osborne H; Waldmeier P; Bettler B
    Eur J Neurosci; 2003 Nov; 18(10):2722-30. PubMed ID: 14656321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of the behavioral effects of gamma-hydroxybutyric acid (GHB) and its 4-methyl-substituted analog, gamma-hydroxyvaleric acid (GHV).
    Carter LP; Chen W; Wu H; Mehta AK; Hernandez RJ; Ticku MK; Coop A; Koek W; France CP
    Drug Alcohol Depend; 2005 Apr; 78(1):91-9. PubMed ID: 15769562
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic GHB precursor succinate binds to gamma-hydroxybutyrate receptors: characterization of human basal ganglia areas nucleus accumbens and globus pallidus.
    Molnár T; Fekete EK; Kardos J; Simon-Trompler E; Palkovits M; Emri Z
    J Neurosci Res; 2006 Jul; 84(1):27-36. PubMed ID: 16673403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands.
    Chen W; Wu H; Hernandez RJ; Mehta AK; Ticku MK; France CP; Coop A
    Bioorg Med Chem Lett; 2005 Jul; 15(13):3201-2. PubMed ID: 15927467
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Monastrol, a 3,4-dihydropyrimidin-2(1H)-thione, as structural scaffold for the development of modulators for GHB high-affinity binding sites and α
    Damgaard M; Al-Khawaja A; Nittegaard-Nielsen M; Petersen RF; Wellendorph P; Frølund B
    Eur J Med Chem; 2017 Sep; 138():300-312. PubMed ID: 28683403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB).
    Absalom N; Eghorn LF; Villumsen IS; Karim N; Bay T; Olsen JV; Knudsen GM; Bräuner-Osborne H; Frølund B; Clausen RP; Chebib M; Wellendorph P
    Proc Natl Acad Sci U S A; 2012 Aug; 109(33):13404-9. PubMed ID: 22753476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-chloropropanoic acid (UMB66): a ligand for the gamma-hydroxybutyric acid receptor lacking a 4-hydroxyl group.
    Macias AT; Hernandez RJ; Mehta AK; MacKerell AD; Ticku MK; Coop A
    Bioorg Med Chem; 2004 Apr; 12(7):1643-7. PubMed ID: 15028257
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin.
    Eghorn LF; Hoestgaard-Jensen K; Kongstad KT; Bay T; Higgins D; Frølund B; Wellendorph P
    Eur J Pharmacol; 2014 Oct; 740():570-7. PubMed ID: 24973695
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Succinic semialdehyde dehydrogenase deficiency: GABAB receptor-mediated function.
    Buzzi A; Wu Y; Frantseva MV; Perez Velazquez JL; Cortez MA; Liu CC; Shen LQ; Gibson KM; Snead OC
    Brain Res; 2006 May; 1090(1):15-22. PubMed ID: 16647690
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes.
    Molnár T; Visy J; Simon A; Moldvai I; Temesvári-Major E; Dörnyei G; Fekete EK; Kardos J
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6290-2. PubMed ID: 18945616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.