BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 19065050)

  • 1. Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.
    Cantley J; Selman C; Shukla D; Abramov AY; Forstreuter F; Esteban MA; Claret M; Lingard SJ; Clements M; Harten SK; Asare-Anane H; Batterham RL; Herrera PL; Persaud SJ; Duchen MR; Maxwell PH; Withers DJ
    J Clin Invest; 2009 Jan; 119(1):125-35. PubMed ID: 19065050
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice.
    Choi D; Cai EP; Schroer SA; Wang L; Woo M
    Lab Invest; 2011 Apr; 91(4):527-38. PubMed ID: 21242957
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The hypoxia response pathway and β-cell function.
    Cantley J; Grey ST; Maxwell PH; Withers DJ
    Diabetes Obes Metab; 2010 Oct; 12 Suppl 2():159-67. PubMed ID: 21029313
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A role for von Hippel-Lindau protein in pancreatic beta-cell function.
    Puri S; Cano DA; Hebrok M
    Diabetes; 2009 Feb; 58(2):433-41. PubMed ID: 19033400
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice.
    Puri S; García-Núñez A; Hebrok M; Cano DA
    PLoS One; 2013; 8(8):e72213. PubMed ID: 23977255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis.
    Brunt JJ; Shi SY; Schroer SA; Sivasubramaniyam T; Cai EP; Woo M
    Islets; 2014; 6(5-6):e1006075. PubMed ID: 25833250
    [TBL] [Abstract][Full Text] [Related]  

  • 7. von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling expression of glucose transporter 2 and glucose 6-phosphatase.
    Park SK; Haase VH; Johnson RS
    Int J Oncol; 2007 Feb; 30(2):341-8. PubMed ID: 17203215
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.
    Zehetner J; Danzer C; Collins S; Eckhardt K; Gerber PA; Ballschmieter P; Galvanovskis J; Shimomura K; Ashcroft FM; Thorens B; Rorsman P; Krek W
    Genes Dev; 2008 Nov; 22(22):3135-46. PubMed ID: 19056893
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conditional VHL gene deletion causes hypoglycemic death associated with disproportionately increased glucose uptake by hepatocytes through an upregulated IGF-I receptor.
    Kurabayashi A; Kakinuma Y; Morita T; Inoue K; Sato T; Furihata M
    PLoS One; 2013; 8(7):e69139. PubMed ID: 23874892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.
    Beall C; Piipari K; Al-Qassab H; Smith MA; Parker N; Carling D; Viollet B; Withers DJ; Ashford ML
    Biochem J; 2010 Jul; 429(2):323-33. PubMed ID: 20465544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pancreatic endocrine microadenomatosis in patients with von Hippel-Lindau disease: characterization by VHL/HIF pathway proteins expression.
    Périgny M; Hammel P; Corcos O; Larochelle O; Giraud S; Richard S; Sauvanet A; Belghiti J; Ruszniewski P; Bedossa P; Couvelard A
    Am J Surg Pathol; 2009 May; 33(5):739-48. PubMed ID: 19238077
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.
    Merlo A; Bernardo-Castiñeira C; Sáenz-de-Santa-María I; Pitiot AS; Balbín M; Astudillo A; Valdés N; Scola B; Del Toro R; Méndez-Ferrer S; Piruat JI; Suarez C; Chiara MD
    Oncotarget; 2017 Jan; 8(4):6700-6717. PubMed ID: 28036268
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.
    Macías D; Fernández-Agüera MC; Bonilla-Henao V; López-Barneo J
    EMBO Mol Med; 2014 Dec; 6(12):1577-92. PubMed ID: 25385837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner.
    Kai S; Tanaka T; Daijo H; Harada H; Kishimoto S; Suzuki K; Takabuchi S; Takenaga K; Fukuda K; Hirota K
    Antioxid Redox Signal; 2012 Feb; 16(3):203-16. PubMed ID: 22004513
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets.
    Cheng K; Ho K; Stokes R; Scott C; Lau SM; Hawthorne WJ; O'Connell PJ; Loudovaris T; Kay TW; Kulkarni RN; Okada T; Wang XL; Yim SH; Shah Y; Grey ST; Biankin AV; Kench JG; Laybutt DR; Gonzalez FJ; Kahn CR; Gunton JE
    J Clin Invest; 2010 Jun; 120(6):2171-83. PubMed ID: 20440072
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis.
    Collier JJ; Batdorf HM; Martin TM; Rohli KE; Burk DH; Lu D; Cooley CR; Karlstad MD; Jackson JW; Sparer TE; Zhang J; Mynatt RL; Burke SJ
    Mol Metab; 2021 Feb; 44():101140. PubMed ID: 33285301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus.
    Puri S; Akiyama H; Hebrok M
    Genes Dev; 2013 Dec; 27(23):2563-75. PubMed ID: 24298056
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia-inducible factor-1 mediates pancreatic β-cell dysfunction by intermittent hypoxia.
    Wang N; Shi XF; Khan SA; Wang B; Semenza GL; Prabhakar NR; Nanduri J
    Am J Physiol Cell Physiol; 2020 Nov; 319(5):C922-C932. PubMed ID: 32936698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism.
    Leisz S; Schulz K; Erb S; Oefner P; Dettmer K; Mougiakakos D; Wang E; Marincola FM; Stehle F; Seliger B
    Oncotarget; 2015 May; 6(13):11395-406. PubMed ID: 25890500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.