138 related articles for article (PubMed ID: 19065645)
1. Assessing the bioisosterism of the trifluoromethyl group with a protease probe.
Jagodzinska M; Huguenot F; Candiani G; Zanda M
ChemMedChem; 2009 Jan; 4(1):49-51. PubMed ID: 19065645
[No Abstract] [Full Text] [Related]
2. Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases.
Faust A; Waschkau B; Waldeck J; Höltke C; Breyholz HJ; Wagner S; Kopka K; Heindel W; Schäfers M; Bremer C
Bioconjug Chem; 2008 May; 19(5):1001-8. PubMed ID: 18396900
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of chiral 2-(4-phenoxyphenylsulfonylmethyl)thiiranes as selective gelatinase inhibitors.
Lee M; Bernardo MM; Meroueh SO; Brown S; Fridman R; Mobashery S
Org Lett; 2005 Sep; 7(20):4463-5. PubMed ID: 16178559
[TBL] [Abstract][Full Text] [Related]
4. C-5-disubstituted barbiturates as potential molecular probes for noninvasive matrix metalloproteinase imaging.
Breyholz HJ; Schäfers M; Wagner S; Höltke C; Faust A; Rabeneck H; Levkau B; Schober O; Kopka K
J Med Chem; 2005 May; 48(9):3400-9. PubMed ID: 15857146
[TBL] [Abstract][Full Text] [Related]
5. Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).
Duan JJ; Chen L; Lu Z; Jiang B; Asakawa N; Sheppeck JE; Liu RQ; Covington MB; Pitts W; Kim SH; Decicco CP
Bioorg Med Chem Lett; 2007 Jan; 17(1):266-71. PubMed ID: 17027261
[TBL] [Abstract][Full Text] [Related]
6. Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.
Moroy G; Denhez C; El Mourabit H; Toribio A; Dassonville A; Decarme M; Renault JH; Mirand C; Bellon G; Sapi J; Alix AJ; Hornebeck W; Bourguet E
Bioorg Med Chem; 2007 Jul; 15(14):4753-66. PubMed ID: 17512742
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties.
Zhang M; Nguyen JT; Kumada HO; Kimura T; Cheng M; Hayashi Y; Kiso Y
Bioorg Med Chem; 2008 May; 16(10):5795-802. PubMed ID: 18400502
[TBL] [Abstract][Full Text] [Related]
8. 1-Hydroxy-2-pyridinone-based MMP inhibitors: synthesis and biological evaluation for the treatment of ischemic stroke.
Zhang YM; Fan X; Chakaravarty D; Xiang B; Scannevin RH; Huang Z; Ma J; Burke SL; Karnachi P; Rhodes KJ; Jackson PF
Bioorg Med Chem Lett; 2008 Jan; 18(1):409-13. PubMed ID: 17981034
[TBL] [Abstract][Full Text] [Related]
9. Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.
Ledour G; Moroy G; Rouffet M; Bourguet E; Guillaume D; Decarme M; Elmourabit H; Augé F; Alix AJ; Laronze JY; Bellon G; Hornebeck W; Sapi J
Bioorg Med Chem; 2008 Sep; 16(18):8745-59. PubMed ID: 18782669
[TBL] [Abstract][Full Text] [Related]
10. Iterative oxime bond chemistry leads to protease inhibitors.
Renaudet O; Reymond JL
Org Lett; 2003 Nov; 5(24):4693-6. PubMed ID: 14627417
[TBL] [Abstract][Full Text] [Related]
11. Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs).
Zhang YM; Fan X; Yang SM; Scannevin RH; Burke SL; Rhodes KJ; Jackson PF
Bioorg Med Chem Lett; 2008 Jan; 18(1):405-8. PubMed ID: 17980583
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of new sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Cheng XC; Wang Q; Fang H; Tang W; Xu WF
Bioorg Med Chem; 2008 Sep; 16(17):7932-8. PubMed ID: 18718763
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors.
Nuti E; Panelli L; Casalini F; Avramova SI; Orlandini E; Santamaria S; Nencetti S; Tuccinardi T; Martinelli A; Cercignani G; D'Amelio N; Maiocchi A; Uggeri F; Rossello A
J Med Chem; 2009 Oct; 52(20):6347-61. PubMed ID: 19775099
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines.
Soroka A; Van der Veken P; De Meester I; Lambeir AM; Maes MB; Scharpé S; Haemers A; Augustyns K
Bioorg Med Chem Lett; 2006 Sep; 16(18):4777-9. PubMed ID: 16844373
[TBL] [Abstract][Full Text] [Related]
15. Metabolism of a highly selective gelatinase inhibitor generates active metabolite.
Lee M; Villegas-Estrada A; Celenza G; Boggess B; Toth M; Kreitinger G; Forbes C; Fridman R; Mobashery S; Chang M
Chem Biol Drug Des; 2007 Nov; 70(5):371-82. PubMed ID: 17927722
[TBL] [Abstract][Full Text] [Related]
16. Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family Polyclinidae.
Fujita M; Nakao Y; Matsunaga S; Nishikawa T; Fusetani N
J Nat Prod; 2002 Dec; 65(12):1936-8. PubMed ID: 12502345
[TBL] [Abstract][Full Text] [Related]
17. The synthesis and preliminary activity assay in vitro of peptide-like derivatives as APN inhibitors.
Li SH; Li G; Huang HM; Xiong F; Liu CM; Tu GG
Arch Pharm Res; 2008 Oct; 31(10):1231-9. PubMed ID: 18958412
[TBL] [Abstract][Full Text] [Related]
18. Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN).
Shang L; Wang Q; Fang H; Mu J; Wang X; Yuan Y; Wang B; Xu W
Bioorg Med Chem; 2008 Dec; 16(23):9984-90. PubMed ID: 18996018
[TBL] [Abstract][Full Text] [Related]
19. Nitrone [2+3]-cycloadditions in stereocontrolled synthesis of a potent proteasome inhibitor: (-)-omuralide.
Legeay JC; Langlois N
J Org Chem; 2007 Dec; 72(26):10108-13. PubMed ID: 18044922
[TBL] [Abstract][Full Text] [Related]
20. Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosing.
Nantermet PG; Rajapakse HA; Stanton MG; Stauffer SR; Barrow JC; Gregro AR; Moore KP; Steinbeiser MA; Swestock J; Selnick HG; Graham SL; McGaughey GB; Colussi D; Lai MT; Sankaranarayanan S; Simon AJ; Munshi S; Cook JJ; Holahan MA; Michener MS; Vacca JP
ChemMedChem; 2009 Jan; 4(1):37-40. PubMed ID: 19085994
[No Abstract] [Full Text] [Related]
[Next] [New Search]