163 related articles for article (PubMed ID: 19067547)
1. Mechanism by which a glutamine to leucine substitution at residue 509 in the ribonuclease H domain of HIV-1 reverse transcriptase confers zidovudine resistance.
Brehm JH; Mellors JW; Sluis-Cremer N
Biochemistry; 2008 Dec; 47(52):14020-7. PubMed ID: 19067547
[TBL] [Abstract][Full Text] [Related]
2. Zidovudine (AZT) monotherapy selects for the A360V mutation in the connection domain of HIV-1 reverse transcriptase.
Brehm JH; Scott Y; Koontz DL; Perry S; Hammer S; Katzenstein D; Mellors JW; Sluis-Cremer N;
PLoS One; 2012; 7(2):e31558. PubMed ID: 22363673
[TBL] [Abstract][Full Text] [Related]
3. Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.
Brehm JH; Koontz D; Meteer JD; Pathak V; Sluis-Cremer N; Mellors JW
J Virol; 2007 Aug; 81(15):7852-9. PubMed ID: 17507476
[TBL] [Abstract][Full Text] [Related]
4. Subunit-specific mutational analysis of residue N348 in HIV-1 reverse transcriptase.
Radzio J; Sluis-Cremer N
Retrovirology; 2011 Aug; 8():69. PubMed ID: 21859446
[TBL] [Abstract][Full Text] [Related]
5. Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase.
Arion D; Kaushik N; McCormick S; Borkow G; Parniak MA
Biochemistry; 1998 Nov; 37(45):15908-17. PubMed ID: 9843396
[TBL] [Abstract][Full Text] [Related]
6. Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.
Ehteshami M; Beilhartz GL; Scarth BJ; Tchesnokov EP; McCormick S; Wynhoven B; Harrigan PR; Götte M
J Biol Chem; 2008 Aug; 283(32):22222-32. PubMed ID: 18547911
[TBL] [Abstract][Full Text] [Related]
7. Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance.
Delviks-Frankenberry KA; Nikolenko GN; Barr R; Pathak VK
J Virol; 2007 Jul; 81(13):6837-45. PubMed ID: 17428874
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanism of HIV-1 resistance to 3'-azido-2',3'-dideoxyguanosine.
Meteer JD; Schinazi RF; Mellors JW; Sluis-Cremer N
Antiviral Res; 2014 Jan; 101():62-7. PubMed ID: 24211331
[TBL] [Abstract][Full Text] [Related]
9. Amino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway.
Álvarez M; Nevot M; Mendieta J; Martínez MA; Menéndez-Arias L
J Biol Chem; 2018 Feb; 293(7):2247-2259. PubMed ID: 29275329
[TBL] [Abstract][Full Text] [Related]
10. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
11. A role of template cleavage in reduced excision of chain-terminating nucleotides by human immunodeficiency virus type 1 reverse transcriptase containing the M184V mutation.
Acosta-Hoyos AJ; Matsuura SE; Meyer PR; Scott WA
J Virol; 2012 May; 86(9):5122-33. PubMed ID: 22379084
[TBL] [Abstract][Full Text] [Related]
12. Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision.
Radzio J; Sluis-Cremer N
Mol Pharmacol; 2008 Feb; 73(2):601-6. PubMed ID: 18024510
[TBL] [Abstract][Full Text] [Related]
13. The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Selmi B; Deval J; Alvarez K; Boretto J; Sarfati S; Guerreiro C; Canard B
J Biol Chem; 2003 Oct; 278(42):40464-72. PubMed ID: 12902345
[TBL] [Abstract][Full Text] [Related]
14. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
15. Nucleocapsid Protein Precursors NCp9 and NCp15 Suppress ATP-Mediated Rescue of AZT-Terminated Primers by HIV-1 Reverse Transcriptase.
Árquez MA; Martín-Alonso S; Gorelick RJ; Scott WA; Acosta-Hoyos AJ; Menéndez-Arias L
Antimicrob Agents Chemother; 2020 Sep; 64(10):. PubMed ID: 32747359
[TBL] [Abstract][Full Text] [Related]
16. Subtype-specific differences in the human immunodeficiency virus type 1 reverse transcriptase connection subdomain of CRF01_AE are associated with higher levels of resistance to 3'-azido-3'-deoxythymidine.
Delviks-Frankenberry KA; Nikolenko GN; Maldarelli F; Hase S; Takebe Y; Pathak VK
J Virol; 2009 Sep; 83(17):8502-13. PubMed ID: 19553318
[TBL] [Abstract][Full Text] [Related]
17. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
[TBL] [Abstract][Full Text] [Related]
18. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
[TBL] [Abstract][Full Text] [Related]
19. Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Canard B; Sarfati SR; Richardson CC
J Biol Chem; 1998 Jun; 273(23):14596-604. PubMed ID: 9603976
[TBL] [Abstract][Full Text] [Related]
20. Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase.
Arion D; Sluis-Cremer N; Parniak MA
J Biol Chem; 2000 Mar; 275(13):9251-5. PubMed ID: 10734063
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
