BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

424 related articles for article (PubMed ID: 19074837)

  • 1. Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target.
    Hegde GV; Peterson KJ; Emanuel K; Mittal AK; Joshi AD; Dickinson JD; Kollessery GJ; Bociek RG; Bierman P; Vose JM; Weisenburger DD; Joshi SS
    Mol Cancer Res; 2008 Dec; 6(12):1928-36. PubMed ID: 19074837
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia.
    Ghia EM; Rassenti LZ; Neuberg DS; Blanco A; Yousif F; Smith EN; McPherson JD; Hudson TJ; ; Harismendy O; Frazer KA; Kipps TJ
    Blood; 2019 Jun; 133(25):2651-2663. PubMed ID: 30923040
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interactions between bone marrow stromal microenvironment and B-chronic lymphocytic leukemia cells: any role for Notch, Wnt and Hh signaling pathways?
    Seke Etet PF; Vecchio L; Nwabo Kamdje AH
    Cell Signal; 2012 Jul; 24(7):1433-43. PubMed ID: 22446006
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
    Desch P; Asslaber D; Kern D; Schnidar H; Mangelberger D; Alinger B; Stoecher M; Hofbauer SW; Neureiter D; Tinhofer I; Aberger F; Hartmann TN; Greil R
    Oncogene; 2010 Sep; 29(35):4885-95. PubMed ID: 20603613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival.
    Trimarco V; Ave E; Facco M; Chiodin G; Frezzato F; Martini V; Gattazzo C; Lessi F; Giorgi CA; Visentin A; Castelli M; Severin F; Zambello R; Piazza F; Semenzato G; Trentin L
    Oncotarget; 2015 Dec; 6(39):42130-49. PubMed ID: 26517523
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Different proliferative and survival capacity of CLL-cells in a newly established in vitro model for pseudofollicles.
    Plander M; Seegers S; Ugocsai P; Diermeier-Daucher S; Iványi J; Schmitz G; Hofstädter F; Schwarz S; Orsó E; Knüchel R; Brockhoff G
    Leukemia; 2009 Nov; 23(11):2118-28. PubMed ID: 19657365
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adhesion to bone marrow stroma inhibits apoptosis of chronic lymphocytic leukemia cells.
    Lagneaux L; Delforge A; De Bruyn C; Bernier M; Bron D
    Leuk Lymphoma; 1999 Nov; 35(5-6):445-53. PubMed ID: 10609782
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.
    Balakrishnan K; Burger JA; Wierda WG; Gandhi V
    Blood; 2009 Jan; 113(1):149-53. PubMed ID: 18836097
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutively Photomorphogenic 1 Reduces the Sensitivity of Chronic Lymphocytic Leukemia Cells to Fludarabine Through Promotion of Ubiquitin-Mediated P53 Degradation.
    Fu C; Shi X; Gong Y; Wan Y; Sun Z; Shi H; Wang Z; Marinaccio C; Crispino JD; Xu K
    Cell Physiol Biochem; 2018; 50(6):2314-2328. PubMed ID: 30423551
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physical contact with endothelial cells through β1- and β2- integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells.
    Maffei R; Fiorcari S; Bulgarelli J; Martinelli S; Castelli I; Deaglio S; Debbia G; Fontana M; Coluccio V; Bonacorsi G; Zucchini P; Narni F; Torelli G; Luppi M; Marasca R
    Haematologica; 2012 Jun; 97(6):952-60. PubMed ID: 22207686
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia.
    Olsson A; Norberg M; Okvist A; Derkow K; Choudhury A; Tobin G; Celsing F; Osterborg A; Rosenquist R; Jondal M; Osorio LM
    Br J Cancer; 2007 Sep; 97(6):769-77. PubMed ID: 17726463
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia.
    Joshi AD; Hegde GV; Dickinson JD; Mittal AK; Lynch JC; Eudy JD; Armitage JO; Bierman PJ; Bociek RG; Devetten MP; Vose JM; Joshi SS
    Clin Cancer Res; 2007 Sep; 13(18 Pt 1):5295-304. PubMed ID: 17875758
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6.
    Lu K; Fang XS; Feng LL; Jiang YJ; Zhou XX; Liu X; Li PP; Chen N; Ding M; Wang N; Zhang J; Wang X
    Cancer Lett; 2015 Apr; 359(2):250-8. PubMed ID: 25636517
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling.
    Lorenzo-Herrero S; Sordo-Bahamonde C; Bretones G; Payer ÁR; González-Rodríguez AP; González-García E; Pérez-Escuredo J; Villa-Álvarez M; Núñez LE; Morís F; Gonzalez S; López-Soto A
    Front Immunol; 2019; 10():2455. PubMed ID: 31681329
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells.
    Secchiero P; Corallini F; Barbarotto E; Melloni E; di Iasio MG; Tiribelli M; Zauli G
    J Cell Physiol; 2006 Apr; 207(1):158-64. PubMed ID: 16270354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.
    Kern D; Regl G; Hofbauer SW; Altenhofer P; Achatz G; Dlugosz A; Schnidar H; Greil R; Hartmann TN; Aberger F
    Oncogene; 2015 Oct; 34(42):5341-51. PubMed ID: 25639866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia.
    Morales AA; Olsson A; Celsing F; Osterborg A; Jondal M; Osorio LM
    Int J Cancer; 2005 Feb; 113(5):730-7. PubMed ID: 15499630
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?
    Ruiz i Altaba A
    Cancer Cell; 2008 Oct; 14(4):281-3. PubMed ID: 18835029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD40 triggering enhances fludarabine-induced apoptosis of chronic lymphocytic leukemia B-cells through autocrine release of tumor necrosis factor-alpha and interferon-gama and tumor necrosis factor receptor-I-II upregulation.
    de Totero D; Tazzari PL; Capaia M; Montera MP; Clavio M; Balleari E; Foa R; Gobbi M
    Haematologica; 2003 Feb; 88(2):148-58. PubMed ID: 12604404
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.