BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 19074975)

  • 1. Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans.
    He H; Tran P; Yin H; Smith H; Batard Y; Wang L; Einolf H; Gu H; Mangold JB; Fischer V; Howard D
    Drug Metab Dispos; 2009 Mar; 37(3):536-44. PubMed ID: 19074975
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disposition of vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in rats and dogs.
    He H; Tran P; Yin H; Smith H; Flood D; Kramp R; Filipeck R; Fischer V; Howard D
    Drug Metab Dispos; 2009 Mar; 37(3):545-54. PubMed ID: 19074976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects.
    He YL; Ligueros-Saylan M; Sunkara G; Sabo R; Zhao C; Wang Y; Campestrini J; Pommier F; Dole K; Marion A; Dole WP; Howard D
    J Clin Pharmacol; 2008 Jan; 48(1):85-95. PubMed ID: 17986525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers.
    Sunkara G; Sabo R; Wang Y; He YL; Campestrini J; Rosenberg M; Howard D; Dole WP
    J Clin Pharmacol; 2007 Sep; 47(9):1152-8. PubMed ID: 17656620
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects.
    Ayalasomayajula SP; Dole K; He YL; Ligueros-Saylan M; Wang Y; Campestrini J; Humbert H; Sunkara G
    Curr Med Res Opin; 2007 Dec; 23(12):2913-20. PubMed ID: 17931461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers.
    He YL; Sabo R; Sunkara G; Bizot MN; Riviere GJ; Leon S; Ligueros-Saylan M; Dole WP; Howard D
    J Clin Pharmacol; 2007 Aug; 47(8):998-1004. PubMed ID: 17660482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacokinetics of lipoyl vildagliptin, a novel dipeptidyl peptidase IV inhibitor after oral administration in rats.
    Wang X; Zhang D; Xu W; Liu H; Wang W
    Xenobiotica; 2010 Oct; 40(10):707-12. PubMed ID: 20735236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dipeptidyl peptidase-4 greatly contributes to the hydrolysis of vildagliptin in human liver.
    Asakura M; Fujii H; Atsuda K; Itoh T; Fujiwara R
    Drug Metab Dispos; 2015 Apr; 43(4):477-84. PubMed ID: 25597851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The absolute oral bioavailability and population-based pharmacokinetic modelling of a novel dipeptidylpeptidase-IV inhibitor, vildagliptin, in healthy volunteers.
    He YL; Sadler BM; Sabo R; Balez S; Wang Y; Campestrini J; Laurent A; Ligueros-Saylan M; Howard D
    Clin Pharmacokinet; 2007; 46(9):787-802. PubMed ID: 17713976
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo.
    Asakura M; Fukami T; Nakajima M; Fujii H; Atsuda K; Itoh T; Fujiwara R
    Drug Metab Dispos; 2017 Feb; 45(2):237-245. PubMed ID: 27895112
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers.
    Waldmeier F; Glaenzel U; Wirz B; Oberer L; Schmid D; Seiberling M; Valencia J; Riviere GJ; End P; Vaidyanathan S
    Drug Metab Dispos; 2007 Aug; 35(8):1418-28. PubMed ID: 17510248
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of food on the pharmacokinetics of a vildagliptin/metformin (50/1000 mg) fixed-dose combination tablet in healthy volunteers.
    He YL; Flannery B; Campestrini J; Leon S; Zinny MA; Ligueros-Saylan M; Jarugula V
    Curr Med Res Opin; 2008 Jun; 24(6):1703-9. PubMed ID: 18471347
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans.
    Prakash C; Kamel A; Gummerus J; Wilner K
    Drug Metab Dispos; 1997 Jul; 25(7):863-72. PubMed ID: 9224781
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolic disposition of [14C]bazedoxifene in healthy postmenopausal women.
    Chandrasekaran A; McKeand WE; Sullivan P; DeMaio W; Stoltz R; Scatina J
    Drug Metab Dispos; 2009 Jun; 37(6):1219-25. PubMed ID: 19273530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).
    Brandt I; Joossens J; Chen X; Maes MB; Scharpé S; De Meester I; Lambeir AM
    Biochem Pharmacol; 2005 Jul; 70(1):134-43. PubMed ID: 15907807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Target-mediated metabolism and target-mediated drug disposition of the DPPIV inhibitor AMG 222.
    Greene RJ; Tu H; Gibbs JP; Greg Slatter J
    Xenobiotica; 2011 Nov; 41(11):945-57. PubMed ID: 21867423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetics and metabolism of nateglinide in humans.
    Weaver ML; Orwig BA; Rodriguez LC; Graham ED; Chin JA; Shapiro MJ; McLeod JF; Mangold JB
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):415-21. PubMed ID: 11259325
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The influence of hepatic impairment on the pharmacokinetics of the dipeptidyl peptidase IV (DPP-4) inhibitor vildagliptin.
    He YL; Sabo R; Campestrini J; Wang Y; Ligueros-Saylan M; Lasseter KC; Dilzer SC; Howard D; Dole WP
    Eur J Clin Pharmacol; 2007 Jul; 63(7):677-86. PubMed ID: 17486328
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetics of vildagliptin in patients with varying degrees of renal impairment.
    He YL; Kulmatycki K; Zhang Y; Zhou W; Reynolds C; Ligueros-Saylan M; Taylor A
    Int J Clin Pharmacol Ther; 2013 Sep; 51(9):693-703. PubMed ID: 23782585
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism and excretion of a new antianxiety drug candidate, CP-93,393, in cynomolgus monkeys: identification of the novel pyrimidine ring cleaved metabolites.
    Prakash C; Cui D
    Drug Metab Dispos; 1997 Dec; 25(12):1395-406. PubMed ID: 9394030
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.