These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 19075013)

  • 1. c-Abl phosphorylates Hdmx and regulates its interaction with p53.
    Zuckerman V; Lenos K; Popowicz GM; Silberman I; Grossman T; Marine JC; Holak TA; Jochemsen AG; Haupt Y
    J Biol Chem; 2009 Feb; 284(6):4031-9. PubMed ID: 19075013
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity.
    Phillips A; Teunisse A; Lam S; Lodder K; Darley M; Emaduddin M; Wolf A; Richter J; de Lange J; Verlaan-de Vries M; Lenos K; Böhnke A; Bartel F; Blaydes JP; Jochemsen AG
    J Biol Chem; 2010 Sep; 285(38):29111-27. PubMed ID: 20659896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53.
    Heminger K; Markey M; Mpagi M; Berberich SJ
    Aging (Albany NY); 2009 Jan; 1(1):89-108. PubMed ID: 19946469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
    Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
    Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
    [TBL] [Abstract][Full Text] [Related]  

  • 5. c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF.
    Dias SS; Milne DM; Meek DW
    Oncogene; 2006 Oct; 25(50):6666-71. PubMed ID: 16702947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study.
    Srdanović S; Wolter M; Trinh CH; Ottmann C; Warriner SL; Wilson AJ
    FEBS J; 2022 Sep; 289(17):5341-5358. PubMed ID: 35286747
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hdm2 disrupts HdmX-mediated nuclear export of p53 by sequestering it in nucleus.
    Ni Y; Chen H; Cheng X; Sun B; Wu Z; Zhan Q; Zhuang Z
    Exp Cell Res; 2024 Aug; 441(2):114185. PubMed ID: 39069150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a Structural Determinant for Selective Targeting of HDMX.
    Ben-Nun Y; Seo HS; Harvey EP; Hauseman ZJ; Wales TE; Newman CE; Cathcart AM; Engen JR; Dhe-Paganon S; Walensky LD
    Structure; 2020 Jul; 28(7):847-857.e5. PubMed ID: 32359398
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.
    Meulmeester E; Maurice MM; Boutell C; Teunisse AF; Ovaa H; Abraham TE; Dirks RW; Jochemsen AG
    Mol Cell; 2005 May; 18(5):565-76. PubMed ID: 15916963
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53 promotes its own polyubiquitination by enhancing the HDM2 and HDMX interaction.
    Medina-Medina I; Martínez-Sánchez M; Hernández-Monge J; Fahraeus R; Muller P; Olivares-Illana V
    Protein Sci; 2018 May; 27(5):976-986. PubMed ID: 29524278
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric Interactions by p53 mRNA Govern HDM2 E3 Ubiquitin Ligase Specificity under Different Conditions.
    Medina-Medina I; García-Beltrán P; de la Mora-de la Mora I; Oria-Hernández J; Millot G; Fahraeus R; Reyes-Vivas H; Sampedro JG; Olivares-Illana V
    Mol Cell Biol; 2016 Aug; 36(16):2195-205. PubMed ID: 27215386
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes.
    Kallen J; Goepfert A; Blechschmidt A; Izaac A; Geiser M; Tavares G; Ramage P; Furet P; Masuya K; Lisztwan J
    J Biol Chem; 2009 Mar; 284(13):8812-21. PubMed ID: 19153082
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
    Carr MI; Roderick JE; Zhang H; Woda BA; Kelliher MA; Jones SN
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):15024-15029. PubMed ID: 27956626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation.
    Wang YV; Wade M; Wong E; Li YC; Rodewald LW; Wahl GM
    Proc Natl Acad Sci U S A; 2007 Jul; 104(30):12365-70. PubMed ID: 17640893
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A stapled p53 helix overcomes HDMX-mediated suppression of p53.
    Bernal F; Wade M; Godes M; Davis TN; Whitehead DG; Kung AL; Wahl GM; Walensky LD
    Cancer Cell; 2010 Nov; 18(5):411-22. PubMed ID: 21075307
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HDM2 and HDMX Proteins in Human Cancer.
    Hároníková L; Vojtěšek B
    Klin Onkol; 2018; 31(Suppl 2):63-70. PubMed ID: 31023026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.
    Goldberg Z; Vogt Sionov R; Berger M; Zwang Y; Perets R; Van Etten RA; Oren M; Taya Y; Haupt Y
    EMBO J; 2002 Jul; 21(14):3715-27. PubMed ID: 12110584
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.
    Pereg Y; Lam S; Teunisse A; Biton S; Meulmeester E; Mittelman L; Buscemi G; Okamoto K; Taya Y; Shiloh Y; Jochemsen AG
    Mol Cell Biol; 2006 Sep; 26(18):6819-31. PubMed ID: 16943424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3.
    Patton JT; Mayo LD; Singhi AD; Gudkov AV; Stark GR; Jackson MW
    Cancer Res; 2006 Mar; 66(6):3169-76. PubMed ID: 16540668
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HdmX overexpression inhibits oncogene induced cellular senescence.
    Miller KR; Kelley K; Tuttle R; Berberich SJ
    Cell Cycle; 2010 Aug; 9(16):3376-82. PubMed ID: 20724842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.