These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 19075750)

  • 1. The retinal cGMP phosphodiesterase gamma-subunit - a chameleon.
    Guo LW; Ruoho AE
    Curr Protein Pept Sci; 2008 Dec; 9(6):611-25. PubMed ID: 19075750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrinsically disordered gamma-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure.
    Song J; Guo LW; Muradov H; Artemyev NO; Ruoho AE; Markley JL
    Proc Natl Acad Sci U S A; 2008 Feb; 105(5):1505-10. PubMed ID: 18230733
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional mapping of interacting regions of the photoreceptor phosphodiesterase (PDE6) γ-subunit with PDE6 catalytic dimer, transducin, and regulator of G-protein signaling9-1 (RGS9-1).
    Zhang XJ; Gao XZ; Yao W; Cote RH
    J Biol Chem; 2012 Jul; 287(31):26312-20. PubMed ID: 22665478
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N-terminal half of the cGMP phosphodiesterase gamma-subunit contributes to stabilization of the GTPase-accelerating protein complex.
    Guo LW; Ruoho AE
    J Biol Chem; 2011 Apr; 286(17):15260-7. PubMed ID: 21393250
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.
    Gao Y; Eskici G; Ramachandran S; Poitevin F; Seven AB; Panova O; Skiniotis G; Cerione RA
    Mol Cell; 2020 Oct; 80(2):237-245.e4. PubMed ID: 33007200
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of conformational changes and protein-protein interactions of rod photoreceptor phosphodiesterase (PDE6).
    Matte SL; Laue TM; Cote RH
    J Biol Chem; 2012 Jun; 287(24):20111-21. PubMed ID: 22514270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones.
    Cote RH
    Pflugers Arch; 2021 Sep; 473(9):1377-1391. PubMed ID: 33860373
    [TBL] [Abstract][Full Text] [Related]  

  • 8. One-step purification of bacterially expressed recombinant transducin alpha-subunit and isotopically labeled PDE6 gamma-subunit for NMR analysis.
    Guo LW; Assadi-Porter FM; Grant JE; Wu H; Markley JL; Ruoho AE
    Protein Expr Purif; 2007 Feb; 51(2):187-97. PubMed ID: 16938469
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit.
    Grant JE; Guo LW; Vestling MM; Martemyanov KA; Arshavsky VY; Ruoho AE
    J Biol Chem; 2006 Mar; 281(10):6194-202. PubMed ID: 16407279
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Photoreceptor Phosphodiesterase (PDE6): Structure, Regulatory Mechanisms, and Implications for Treatment of Retinal Diseases.
    Cote RH; Gupta R; Irwin MJ; Wang X
    Adv Exp Med Biol; 2022; 1371():33-59. PubMed ID: 34170501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural requirements of the photoreceptor phosphodiesterase gamma-subunit for inhibition of rod PDE6 holoenzyme and for its activation by transducin.
    Zhang XJ; Skiba NP; Cote RH
    J Biol Chem; 2010 Feb; 285(7):4455-63. PubMed ID: 19948718
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination.
    Wieland T; Chen CK; Simon MI
    J Biol Chem; 1997 Apr; 272(14):8853-6. PubMed ID: 9083000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detergents stabilize the conformation of phosphodiesterase 6.
    Baker BY; Palczewski K
    Biochemistry; 2011 Nov; 50(44):9520-31. PubMed ID: 21978030
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing the catalytic sites and activation mechanism of photoreceptor phosphodiesterase using radiolabeled phosphodiesterase inhibitors.
    Liu YT; Matte SL; Corbin JD; Francis SH; Cote RH
    J Biol Chem; 2009 Nov; 284(46):31541-7. PubMed ID: 19758990
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The N termini of the inhibitory γ-subunits of phosphodiesterase-6 (PDE6) from rod and cone photoreceptors differentially regulate transducin-mediated PDE6 activation.
    Wang X; Plachetzki DC; Cote RH
    J Biol Chem; 2019 May; 294(21):8351-8360. PubMed ID: 30962282
    [TBL] [Abstract][Full Text] [Related]  

  • 16. It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods.
    Qureshi BM; Behrmann E; Schöneberg J; Loerke J; Bürger J; Mielke T; Giesebrecht J; Noé F; Lamb TD; Hofmann KP; Spahn CMT; Heck M
    Open Biol; 2018 Aug; 8(8):. PubMed ID: 30068566
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The molecular architecture of photoreceptor phosphodiesterase 6 (PDE6) with activated G protein elucidates the mechanism of visual excitation.
    Irwin MJ; Gupta R; Gao XZ; Cahill KB; Chu F; Cote RH
    J Biol Chem; 2019 Dec; 294(51):19486-19497. PubMed ID: 31690623
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The gamma subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3.
    Frame M; Wan KF; Tate R; Vandenabeele P; Pyne NJ
    Cell Signal; 2001 Oct; 13(10):735-41. PubMed ID: 11602184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transducin activates cGMP phosphodiesterase by trapping inhibitory γ subunit freed reversibly from the catalytic subunit in solution.
    Asano T; Kawamura S; Tachibanaki S
    Sci Rep; 2019 May; 9(1):7245. PubMed ID: 31076603
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of photoreceptor phosphodiesterase (PDE6) by phosphorylation of its inhibitory gamma subunit re-evaluated.
    Paglia MJ; Mou H; Cote RH
    J Biol Chem; 2002 Feb; 277(7):5017-23. PubMed ID: 11741972
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.