271 related articles for article (PubMed ID: 19079341)
1. Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis.
Liu J; Weiss HL; Rychahou P; Jackson LN; Evers BM; Gao T
Oncogene; 2009 Feb; 28(7):994-1004. PubMed ID: 19079341
[TBL] [Abstract][Full Text] [Related]
2. The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer.
Li X; Stevens PD; Yang H; Gulhati P; Wang W; Evers BM; Gao T
Oncogene; 2013 Jan; 32(4):471-8. PubMed ID: 22391563
[TBL] [Abstract][Full Text] [Related]
3. PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
Li X; Stevens PD; Liu J; Yang H; Wang W; Wang C; Zeng Z; Schmidt MD; Yang M; Lee EY; Gao T
Gastroenterology; 2014 May; 146(5):1301-12.e1-10. PubMed ID: 24530606
[TBL] [Abstract][Full Text] [Related]
4. The phosphatase PHLPP controls the cellular levels of protein kinase C.
Gao T; Brognard J; Newton AC
J Biol Chem; 2008 Mar; 283(10):6300-11. PubMed ID: 18162466
[TBL] [Abstract][Full Text] [Related]
5. PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth.
Liu J; Stevens PD; Li X; Schmidt MD; Gao T
Mol Cell Biol; 2011 Dec; 31(24):4917-27. PubMed ID: 21986499
[TBL] [Abstract][Full Text] [Related]
6. PHLPPing through history: a decade in the life of PHLPP phosphatases.
Grzechnik AT; Newton AC
Biochem Soc Trans; 2016 Dec; 44(6):1675-1682. PubMed ID: 27913677
[TBL] [Abstract][Full Text] [Related]
7. Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C.
Xiong X; Li X; Wen YA; Gao T
J Biol Chem; 2016 Nov; 291(48):25167-25178. PubMed ID: 27760826
[TBL] [Abstract][Full Text] [Related]
8. SNORA74B gene silencing inhibits gallbladder cancer cells by inducing PHLPP and suppressing Akt/mTOR signaling.
Qin Y; Meng L; Fu Y; Quan Z; Ma M; Weng M; Zhang Z; Gao C; Shi X; Han K
Oncotarget; 2017 Mar; 8(12):19980-19996. PubMed ID: 28212545
[TBL] [Abstract][Full Text] [Related]
9. PHLiPPing the switch on Akt and protein kinase C signaling.
Brognard J; Newton AC
Trends Endocrinol Metab; 2008 Aug; 19(6):223-30. PubMed ID: 18511290
[TBL] [Abstract][Full Text] [Related]
10. The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation.
Nitsche C; Edderkaoui M; Moore RM; Eibl G; Kasahara N; Treger J; Grippo PJ; Mayerle J; Lerch MM; Gukovskaya AS
Gastroenterology; 2012 Feb; 142(2):377-87.e1-5. PubMed ID: 22044669
[TBL] [Abstract][Full Text] [Related]
11. mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
Liu J; Stevens PD; Gao T
J Biol Chem; 2011 Feb; 286(8):6510-20. PubMed ID: 21177869
[TBL] [Abstract][Full Text] [Related]
12. On the PHLPPside: Emerging roles of PHLPP phosphatases in the heart.
Lemoine KA; Fassas JM; Ohannesian SH; Purcell NH
Cell Signal; 2021 Oct; 86():110097. PubMed ID: 34320369
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes.
Jackson TC; Verrier JD; Drabek T; Janesko-Feldman K; Gillespie DG; Uray T; Dezfulian C; Clark RS; Bayir H; Jackson EK; Kochanek PM
J Pharmacol Exp Ther; 2013 Nov; 347(2):516-28. PubMed ID: 24023368
[TBL] [Abstract][Full Text] [Related]
14. PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.
Brognard J; Sierecki E; Gao T; Newton AC
Mol Cell; 2007 Mar; 25(6):917-31. PubMed ID: 17386267
[TBL] [Abstract][Full Text] [Related]
15. Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.
Warfel NA; Newton AC
J Biol Chem; 2012 Feb; 287(6):3610-6. PubMed ID: 22144674
[TBL] [Abstract][Full Text] [Related]
16. PHLPP isoforms differentially regulate Akt isoforms and AS160 affecting neuronal insulin signaling and insulin resistance via Scribble.
Sharma M; Dey CS
Cell Commun Signal; 2022 Nov; 20(1):179. PubMed ID: 36376971
[TBL] [Abstract][Full Text] [Related]
17. Aberrant expression of PHLPP1 and PHLPP2 correlates with poor prognosis in patients with hypopharyngeal squamous cell carcinoma.
Zhou J; Yu X; Wang J; Li T; Jin T; Lei D; Pan X
PLoS One; 2015; 10(3):e0119405. PubMed ID: 25793736
[TBL] [Abstract][Full Text] [Related]
18. Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance.
Andreozzi F; Procopio C; Greco A; Mannino GC; Miele C; Raciti GA; Iadicicco C; Beguinot F; Pontiroli AE; Hribal ML; Folli F; Sesti G
Diabetologia; 2011 Jul; 54(7):1879-87. PubMed ID: 21461637
[TBL] [Abstract][Full Text] [Related]
19. Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling
Chern Y; Zhang P; Ju H; Tai IT
Cancer Biol Med; 2020 May; 17(2):343-356. PubMed ID: 32587773
[No Abstract] [Full Text] [Related]
20. miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer.
Cai J; Fang L; Huang Y; Li R; Yuan J; Yang Y; Zhu X; Chen B; Wu J; Li M
Cancer Res; 2013 Sep; 73(17):5402-15. PubMed ID: 23856247
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
