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5. Pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase (PNP) inhibitors as potential T-cell selective immunosuppressive agents. Sircar JC; Kostlan CR; Gilbertsen RB; Dong MK; Cetenko WA Adv Exp Med Biol; 1991; 309A():45-8. PubMed ID: 1789265 [TBL] [Abstract][Full Text] [Related]
6. The biochemistry and pharmacology of PD 116124 (8-amino-2'-nordeoxyguanosine), an inhibitor of purine nucleoside phosphorylase (PNP). Dong MK; Scott ME; Schrier DJ; Suto MJ; Sircar JC; Black A; Chang T; Gilbertsen RB J Pharmacol Exp Ther; 1992 Jan; 260(1):319-26. PubMed ID: 1530976 [TBL] [Abstract][Full Text] [Related]
7. Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency. Fairbanks LD; Taddeo A; Duley JA; Simmonds HA J Immunol; 1990 Jan; 144(2):485-91. PubMed ID: 2104895 [TBL] [Abstract][Full Text] [Related]
8. Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955. Gilbertsen RB; Josyula U; Sircar JC; Dong MK; Wu WS; Wilburn DJ; Conroy MC Biochem Pharmacol; 1992 Sep; 44(5):996-9. PubMed ID: 1530667 [TBL] [Abstract][Full Text] [Related]
9. PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. I. Suppression of the human mixed lymphocyte reaction (MLR). Wilburn DJ; Dong MK; Gilbertsen RB Agents Actions; 1993; 39 Spec No():C96-8. PubMed ID: 8273599 [TBL] [Abstract][Full Text] [Related]
10. A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells. Posmantur R; Wang KK; Nath R; Gilbertsen RB Immunopharmacology; 1997 Oct; 37(2-3):231-44. PubMed ID: 9403342 [TBL] [Abstract][Full Text] [Related]
11. Mechanisms of deoxyguanosine toxicity for human T and B lymphocytes. Scharenberg JG; Spaapen LJ; Rijkers GT; Wadman SK; Staal GE; Zegers BJ Adv Exp Med Biol; 1986; 195 Pt B():191-9. PubMed ID: 3094325 [No Abstract] [Full Text] [Related]
12. Activities of two 9-deazaguanine analogue inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955, in vitro and in vivo. Gilbertsen RB; Dong MK; Josyula U; Sircar JC; Wilburn DJ; Conroy MC Ann N Y Acad Sci; 1993 Jun; 685():248-51. PubMed ID: 8363228 [No Abstract] [Full Text] [Related]
13. PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. II. Effects on nucleoside catabolism in human and rat blood in vitro. Dong MK; Gilbertsen RB Agents Actions; 1993; 39 Spec No():C99-101. PubMed ID: 8273600 [TBL] [Abstract][Full Text] [Related]
14. Functional and mechanistic studies on the toxicity of deoxyguanosine for the in vitro proliferation and differentiation of human peripheral blood B lymphocytes. Scharenberg JG; Spaapen LJ; Rijkers GT; Duran M; Staal GE; Zegers BJ Eur J Immunol; 1986 Apr; 16(4):381-7. PubMed ID: 3084280 [TBL] [Abstract][Full Text] [Related]
15. Effect of immunosuppressive agents on human T and B lymphoblasts. Kazmers IS; Daddona PE; Dalke AP; Kelley WN Biochem Pharmacol; 1983 Mar; 32(5):805-10. PubMed ID: 6404281 [TBL] [Abstract][Full Text] [Related]
16. Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP. Duan DS; Nagashima T; Hoshino T; Waldman F; Pawlak K; Sadee W Biochem J; 1990 Jun; 268(3):725-31. PubMed ID: 2114100 [TBL] [Abstract][Full Text] [Related]
17. Different pathways for deoxyguanosine toxicity in T-lymphocytes of various developmental stages. Scharenberg JG; Rijkers GT; Spaapen LJ; Toebes EA; Rijksen G; Duran M; Staal GE; Zegers BJ Int J Immunopharmacol; 1988; 10(6):675-86. PubMed ID: 2974022 [TBL] [Abstract][Full Text] [Related]
18. Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777. Bantia S; Ananth SL; Parker CD; Horn LL; Upshaw R Int Immunopharmacol; 2003 Jun; 3(6):879-87. PubMed ID: 12781704 [TBL] [Abstract][Full Text] [Related]