BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 19084516)

  • 1. SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis.
    Klotz K; Cepeda D; Tan Y; Sun D; Sangfelt O; Spruck C
    Exp Cell Res; 2009 Jul; 315(11):1832-9. PubMed ID: 19084516
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differences in degradation lead to asynchronous expression of cyclin E1 and cyclin E2 in cancer cells.
    Caldon CE; Sergio CM; Sutherland RL; Musgrove EA
    Cell Cycle; 2013 Feb; 12(4):596-605. PubMed ID: 23324394
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.
    Fujii Y; Yada M; Nishiyama M; Kamura T; Takahashi H; Tsunematsu R; Susaki E; Nakagawa T; Matsumoto A; Nakayama KI
    Cancer Sci; 2006 Aug; 97(8):729-36. PubMed ID: 16863506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Fbxw7/hCdc4 tumor suppressor in human cancer.
    Tan Y; Sangfelt O; Spruck C
    Cancer Lett; 2008 Nov; 271(1):1-12. PubMed ID: 18541364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FBXW7/hCDC4 is a general tumor suppressor in human cancer.
    Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Cepeda D; Fiegl H; Dafou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C
    Cancer Res; 2007 Oct; 67(19):9006-12. PubMed ID: 17909001
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
    Hao B; Oehlmann S; Sowa ME; Harper JW; Pavletich NP
    Mol Cell; 2007 Apr; 26(1):131-43. PubMed ID: 17434132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.
    Bhaskaran N; van Drogen F; Ng HF; Kumar R; Ekholm-Reed S; Peter M; Sangfelt O; Reed SI
    Mol Cell Biol; 2013 Jan; 33(1):85-97. PubMed ID: 23109421
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
    J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms.
    van Drogen F; Sangfelt O; Malyukova A; Matskova L; Yeh E; Means AR; Reed SI
    Mol Cell; 2006 Jul; 23(1):37-48. PubMed ID: 16818231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. hCDC4 gene mutations in endometrial cancer.
    Spruck CH; Strohmaier H; Sangfelt O; Müller HM; Hubalek M; Müller-Holzner E; Marth C; Widschwendter M; Reed SI
    Cancer Res; 2002 Aug; 62(16):4535-9. PubMed ID: 12183400
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Both SCF(Cdc4alpha) and SCF(Cdc4gamma) are required for cyclin E turnover in cell lines that do not overexpress cyclin E.
    Sangfelt O; Cepeda D; Malyukova A; van Drogen F; Reed SI
    Cell Cycle; 2008 Apr; 7(8):1075-82. PubMed ID: 18414042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fbw7 isoform interaction contributes to cyclin E proteolysis.
    Zhang W; Koepp DM
    Mol Cancer Res; 2006 Dec; 4(12):935-43. PubMed ID: 17189384
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E.
    Wang H; Zhang X; Geng L; Teng L; Legerski RJ
    J Biol Chem; 2009 Jul; 284(27):18236-43. PubMed ID: 19423708
    [TBL] [Abstract][Full Text] [Related]  

  • 14. E3 ubiquitin ligase FBW7α inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.
    Li M; Ouyang L; Zheng Z; Xiang D; Ti A; Li L; Dan Y; Yu C; Li W
    Oncol Rep; 2017 Mar; 37(3):1627-1636. PubMed ID: 28184929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.
    Willems AR; Goh T; Taylor L; Chernushevich I; Shevchenko A; Tyers M
    Philos Trans R Soc Lond B Biol Sci; 1999 Sep; 354(1389):1533-50. PubMed ID: 10582239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
    Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
    EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
    Strohmaier H; Spruck CH; Kaiser P; Won KA; Sangfelt O; Reed SI
    Nature; 2001 Sep; 413(6853):316-22. PubMed ID: 11565034
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
    Tu K; Zheng X; Zhou Z; Li C; Zhang J; Gao J; Yao Y; Liu Q
    PLoS One; 2013; 8(7):e68574. PubMed ID: 23840897
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The PP2A-B56 Phosphatase Opposes Cyclin E Autocatalytic Degradation via Site-Specific Dephosphorylation.
    Davis RJ; Swanger J; Hughes BT; Clurman BE
    Mol Cell Biol; 2017 Apr; 37(8):. PubMed ID: 28137908
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4).
    Cizmecioglu O; Krause A; Bahtz R; Ehret L; Malek N; Hoffmann I
    J Cell Sci; 2012 Feb; 125(Pt 4):981-92. PubMed ID: 22399798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.