234 related articles for article (PubMed ID: 19089010)
1. Theoretical study of N-dealkylation of N-cyclopropyl-N-methylaniline catalyzed by cytochrome P450: insight into the origin of the regioselectivity.
Li D; Wang Y; Yang C; Han K
Dalton Trans; 2009 Jan; (2):291-7. PubMed ID: 19089010
[TBL] [Abstract][Full Text] [Related]
2. Theoretical study of N-demethylation of substituted N,N-dimethylanilines by cytochrome P450: the mechanistic significance of kinetic isotope effect profiles.
Wang Y; Kumar D; Yang C; Han K; Shaik S
J Phys Chem B; 2007 Jul; 111(26):7700-10. PubMed ID: 17559261
[TBL] [Abstract][Full Text] [Related]
3. Cytochrome P450-catalyzed oxidation of N-benzyl-N-cyclopropylamine generates both cyclopropanone hydrate and 3-hydroxypropionaldehyde via hydrogen abstraction, not single electron transfer.
Cerny MA; Hanzlik RP
J Am Chem Soc; 2006 Mar; 128(10):3346-54. PubMed ID: 16522116
[TBL] [Abstract][Full Text] [Related]
4. A proton-shuttle mechanism mediated by the porphyrin in benzene hydroxylation by cytochrome p450 enzymes.
de Visser SP; Shaik S
J Am Chem Soc; 2003 Jun; 125(24):7413-24. PubMed ID: 12797816
[TBL] [Abstract][Full Text] [Related]
5. An acyl group makes a difference in the reactivity patterns of cytochrome P450 catalyzed N-demethylation of substituted N,N-dimethylbenzamides-high spin selective reactions.
Wang Y; Li D; Han K; Shaik S
J Phys Chem B; 2010 Mar; 114(8):2964-70. PubMed ID: 20146528
[TBL] [Abstract][Full Text] [Related]
6. Probing the Compound I-like reactivity of a bare high-valent oxo iron porphyrin complex: the oxidation of tertiary amines.
Chiavarino B; Cipollini R; Crestoni ME; Fornarini S; Lanucara F; Lapi A
J Am Chem Soc; 2008 Mar; 130(10):3208-17. PubMed ID: 18278912
[TBL] [Abstract][Full Text] [Related]
7. Studies on the cytochrome P450 catalyzed oxidation of 13C labeled 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine by 13C NMR.
Bissel P; Castagnoli N; Penich S
Bioorg Med Chem; 2005 Apr; 13(8):2975-80. PubMed ID: 15781407
[TBL] [Abstract][Full Text] [Related]
8. Kinetic isotope effect is a sensitive probe of spin state reactivity in C-H hydroxylation of N,N-dimethylaniline by cytochrome P450.
Li C; Wu W; Kumar D; Shaik S
J Am Chem Soc; 2006 Jan; 128(2):394-5. PubMed ID: 16402810
[TBL] [Abstract][Full Text] [Related]
9. Rate-limiting steps in cytochrome P450 catalysis.
Guengerich FP
Biol Chem; 2002 Oct; 383(10):1553-64. PubMed ID: 12452431
[TBL] [Abstract][Full Text] [Related]
10. Anilinic N-oxides support cytochrome P450-mediated N-dealkylation through hydrogen-atom transfer.
Roberts KM; Jones JP
Chemistry; 2010 Jul; 16(27):8096-107. PubMed ID: 20521282
[TBL] [Abstract][Full Text] [Related]
11. Elucidation of the mechanism of N-demethylation catalyzed by cytochrome P450 monooxygenase is facilitated by exploiting nitrogen-15 heavy isotope effects.
Kwiecień RA; Molinié R; Paneth P; Silvestre V; Lebreton J; Robins RJ
Arch Biochem Biophys; 2011 Jun; 510(1):35-41. PubMed ID: 21420927
[TBL] [Abstract][Full Text] [Related]
12. Formation of cyclopropanone during cytochrome P450-catalyzed N-dealkylation of a cyclopropylamine.
Shaffer CL; Harriman S; Koen YM; Hanzlik RP
J Am Chem Soc; 2002 Jul; 124(28):8268-74. PubMed ID: 12105905
[TBL] [Abstract][Full Text] [Related]
13. Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules.
Wang Y; Chen H; Makino M; Shiro Y; Nagano S; Asamizu S; Onaka H; Shaik S
J Am Chem Soc; 2009 May; 131(19):6748-62. PubMed ID: 19385626
[TBL] [Abstract][Full Text] [Related]
14. A theoretical study on the mechanism of camphor hydroxylation by compound I of cytochrome p450.
Kamachi T; Yoshizawa K
J Am Chem Soc; 2003 Apr; 125(15):4652-61. PubMed ID: 12683838
[TBL] [Abstract][Full Text] [Related]
15. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
Kim KH; Isin EM; Yun CH; Kim DH; Guengerich FP
FEBS J; 2006 May; 273(10):2223-31. PubMed ID: 16649998
[TBL] [Abstract][Full Text] [Related]
16. On the mechanism of amine oxidations by P450.
Karki SB; Dinnocenzo JP
Xenobiotica; 1995 Jul; 25(7):711-24. PubMed ID: 7483668
[TBL] [Abstract][Full Text] [Related]
17. Radical clock substrates, their C-H hydroxylation mechanism by cytochrome P450, and other reactivity patterns: what does theory reveal about the clocks' behavior?
Kumar D; de Visser SP; Sharma PK; Cohen S; Shaik S
J Am Chem Soc; 2004 Feb; 126(6):1907-20. PubMed ID: 14871124
[TBL] [Abstract][Full Text] [Related]
18. Sulfoxidation mechanisms catalyzed by cytochrome P450 and horseradish peroxidase models: spin selection induced by the ligand.
Kumar D; de Visser SP; Sharma PK; Hirao H; Shaik S
Biochemistry; 2005 Jun; 44(22):8148-58. PubMed ID: 15924434
[TBL] [Abstract][Full Text] [Related]
19. Oxidation of tertiary amines by cytochrome p450-kinetic isotope effect as a spin-state reactivity probe.
Li C; Wu W; Cho KB; Shaik S
Chemistry; 2009 Aug; 15(34):8492-8503. PubMed ID: 19322770
[TBL] [Abstract][Full Text] [Related]
20. Computational evidence for α-nitrosamino radical as initial metabolite for both the P450 dealkylation and denitrosation of carcinogenic nitrosamines.
Ji L; Schüürmann G
J Phys Chem B; 2012 Jan; 116(2):903-12. PubMed ID: 22136655
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
