BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 19090779)

  • 1. Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching.
    Wei D; Jiang X; Zhou L; Chen J; Chen Z; He C; Yang K; Liu Y; Pei J; Lai L
    J Med Chem; 2008 Dec; 51(24):7882-8. PubMed ID: 19090779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.
    Appiah-Kubi P; Soliman M
    Cell Biochem Biophys; 2017 Mar; 75(1):35-48. PubMed ID: 27914004
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase.
    Meng H; Liu Y; Zhai Y; Lai L
    Eur J Med Chem; 2013 Jan; 59():160-7. PubMed ID: 23220644
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of dual target inhibitors against cyclooxygenases and leukotriene A4 hydrolyase.
    Chen Z; Wu Y; Liu Y; Yang S; Chen Y; Lai L
    J Med Chem; 2011 May; 54(10):3650-60. PubMed ID: 21542630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking.
    Audat SA; Al-Shar'i NA; Al-Oudat BA; Bryant-Friedrich A; Bedi MF; Zayed AL; Al-Balas QA
    Molecules; 2020 Jun; 25(12):. PubMed ID: 32580506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular docking and pharmacophore filtering in the discovery of dual-inhibitors for human leukotriene A4 hydrolase and leukotriene C4 synthase.
    Thangapandian S; John S; Sakkiah S; Lee KW
    J Chem Inf Model; 2011 Jan; 51(1):33-44. PubMed ID: 21133343
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-affinity aptamers selectively inhibit human nonpancreatic secretory phospholipase A2 (hnps-PLA2).
    Bridonneau P; Chang YF; O'Connell D; Gill SC; Snyder DW; Johnson L; Goodson T; Herron DK; Parma DH
    J Med Chem; 1998 Mar; 41(6):778-86. PubMed ID: 9526554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives.
    Jiang X; Zhou L; Wei D; Meng H; Liu Y; Lai L
    Bioorg Med Chem Lett; 2008 Dec; 18(24):6549-52. PubMed ID: 18952425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual anti-inflammatory and selective inhibition mechanism of leukotriene A4 hydrolase/aminopeptidase: insights from comparative molecular dynamics and binding free energy analyses.
    Appiah-Kubi P; Soliman ME
    J Biomol Struct Dyn; 2016 Nov; 34(11):2418-33. PubMed ID: 26555301
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diverse ways of perturbing the human arachidonic acid metabolic network to control inflammation.
    Meng H; Liu Y; Lai L
    Acc Chem Res; 2015 Aug; 48(8):2242-50. PubMed ID: 26237215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening.
    Xing L; McDonald JJ; Kolodziej SA; Kurumbail RG; Williams JM; Warren CJ; O'Neal JM; Skepner JE; Roberds SL
    J Med Chem; 2011 Mar; 54(5):1211-22. PubMed ID: 21302953
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unsymmetrical non-adamantyl N,N'-diaryl urea and amide inhibitors of soluble expoxide hydrolase.
    Anandan SK; Webb HK; Do ZN; Gless RD
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4259-63. PubMed ID: 19520575
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
    Khim SK; Bauman J; Evans J; Freeman B; King B; Kirkland T; Kochanny M; Lentz D; Liang A; Mendoza L; Phillips G; Tseng JL; Wei RG; Ye H; Yu L; Parkinson J; Guilford WJ
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3895-8. PubMed ID: 18590959
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of DPP IV inhibitors by pharmacophore modeling and QSAR analysis followed by in silico screening.
    Al-Masri IM; Mohammad MK; Taha MO
    ChemMedChem; 2008 Nov; 3(11):1763-79. PubMed ID: 18989859
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular dynamics simulation study and hybrid pharmacophore model development in human LTA4H inhibitor design.
    Thangapandian S; John S; Arooj M; Lee KW
    PLoS One; 2012; 7(4):e34593. PubMed ID: 22496831
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of Potent Soluble Epoxide Hydrolase (sEH) Inhibitors by Pharmacophore-Based Virtual Screening.
    Waltenberger B; Garscha U; Temml V; Liers J; Werz O; Schuster D; Stuppner H
    J Chem Inf Model; 2016 Apr; 56(4):747-62. PubMed ID: 26882208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors.
    Daidone F; Montioli R; Paiardini A; Cellini B; Macchiarulo A; Giardina G; Bossa F; Borri Voltattorni C
    PLoS One; 2012; 7(2):e31610. PubMed ID: 22384042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2).
    Ulmschneider S; Negri M; Voets M; Hartmann RW
    Bioorg Med Chem Lett; 2006 Jan; 16(1):25-30. PubMed ID: 16246562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PENG: a neural gas-based approach for pharmacophore elucidation. method design, validation, and virtual screening for novel ligands of LTA4H.
    Moser D; Wittmann SK; Kramer J; Blöcher R; Achenbach J; Pogoryelov D; Proschak E
    J Chem Inf Model; 2015 Feb; 55(2):284-93. PubMed ID: 25625859
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacophore identification, in silico screening, and virtual library design for inhibitors of the human factor Xa.
    Krovat EM; Frühwirth KH; Langer T
    J Chem Inf Model; 2005; 45(1):146-59. PubMed ID: 15667140
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.