BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 19091752)

  • 1. Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2.
    Liu Y; Hao W; Dawson A; Liu S; Fassbender K
    J Biol Chem; 2009 Feb; 284(6):3691-9. PubMed ID: 19091752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity.
    Li Q; Spencer NY; Pantazis NJ; Engelhardt JF
    J Biol Chem; 2011 Nov; 286(46):40151-62. PubMed ID: 21937428
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Extracellular mutant SOD1 induces microglial-mediated motoneuron injury.
    Zhao W; Beers DR; Henkel JS; Zhang W; Urushitani M; Julien JP; Appel SH
    Glia; 2010 Jan; 58(2):231-43. PubMed ID: 19672969
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The NADPH oxidase pathway is dysregulated by the P2X7 receptor in the SOD1-G93A microglia model of amyotrophic lateral sclerosis.
    Apolloni S; Parisi C; Pesaresi MG; Rossi S; Carrì MT; Cozzolino M; Volonté C; D'Ambrosi N
    J Immunol; 2013 May; 190(10):5187-95. PubMed ID: 23589615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
    Beers DR; Henkel JS; Xiao Q; Zhao W; Wang J; Yen AA; Siklos L; McKercher SR; Appel SH
    Proc Natl Acad Sci U S A; 2006 Oct; 103(43):16021-6. PubMed ID: 17043238
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Iron accumulation promotes TACE-mediated TNF-α secretion and neurodegeneration in a mouse model of ALS.
    Lee JK; Shin JH; Gwag BJ; Choi EJ
    Neurobiol Dis; 2015 Aug; 80():63-9. PubMed ID: 26002422
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1.
    Boillée S; Cleveland DW
    J Clin Invest; 2008 Feb; 118(2):474-8. PubMed ID: 18219386
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia.
    Xiao Q; Zhao W; Beers DR; Yen AA; Xie W; Henkel JS; Appel SH
    J Neurochem; 2007 Sep; 102(6):2008-2019. PubMed ID: 17555556
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis.
    D'Ambrosi N; Finocchi P; Apolloni S; Cozzolino M; Ferri A; Padovano V; Pietrini G; Carrì MT; Volonté C
    J Immunol; 2009 Oct; 183(7):4648-56. PubMed ID: 19734218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis.
    Almer G; Vukosavic S; Romero N; Przedborski S
    J Neurochem; 1999 Jun; 72(6):2415-25. PubMed ID: 10349851
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.
    Martin LJ
    Rev Neurosci; 2007; 18(2):115-36. PubMed ID: 17593875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1.
    Gravel M; Béland LC; Soucy G; Abdelhamid E; Rahimian R; Gravel C; Kriz J
    J Neurosci; 2016 Jan; 36(3):1031-48. PubMed ID: 26791230
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS.
    Liao B; Zhao W; Beers DR; Henkel JS; Appel SH
    Exp Neurol; 2012 Sep; 237(1):147-52. PubMed ID: 22735487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis.
    Tada S; Okuno T; Yasui T; Nakatsuji Y; Sugimoto T; Kikutani H; Sakoda S
    J Neuroinflammation; 2011 Feb; 8():19. PubMed ID: 21345177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1.
    Oono M; Okado-Matsumoto A; Shodai A; Ido A; Ohta Y; Abe K; Ayaki T; Ito H; Takahashi R; Taniguchi N; Urushitani M
    J Neurochem; 2014 Feb; 128(3):403-18. PubMed ID: 24032595
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
    Deora V; Lee JD; Albornoz EA; McAlary L; Jagaraj CJ; Robertson AAB; Atkin JD; Cooper MA; Schroder K; Yerbury JJ; Gordon R; Woodruff TM
    Glia; 2020 Feb; 68(2):407-421. PubMed ID: 31596526
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS).
    Van Dyke JM; Smit-Oistad IM; Macrander C; Krakora D; Meyer MG; Suzuki M
    Exp Neurol; 2016 Mar; 277():275-282. PubMed ID: 26775178
    [TBL] [Abstract][Full Text] [Related]  

  • 18. System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
    Mesci P; Zaïdi S; Lobsiger CS; Millecamps S; Escartin C; Seilhean D; Sato H; Mallat M; Boillée S
    Brain; 2015 Jan; 138(Pt 1):53-68. PubMed ID: 25384799
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
    Gowing G; Philips T; Van Wijmeersch B; Audet JN; Dewil M; Van Den Bosch L; Billiau AD; Robberecht W; Julien JP
    J Neurosci; 2008 Oct; 28(41):10234-44. PubMed ID: 18842883
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats.
    Sanagi T; Nakamura Y; Suzuki E; Uchino S; Aoki M; Warita H; Itoyama Y; Kohsaka S; Ohsawa K
    Glia; 2012 May; 60(5):782-93. PubMed ID: 22344792
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.