These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 1909891)

  • 1. Conformational mobility of His-64 in the Thr-200----Ser mutant of human carbonic anhydrase II.
    Krebs JF; Fierke CA; Alexander RS; Christianson DW
    Biochemistry; 1991 Sep; 30(38):9153-60. PubMed ID: 1909891
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
    Huang CC; Lesburg CA; Kiefer LL; Fierke CA; Christianson DW
    Biochemistry; 1996 Mar; 35(11):3439-46. PubMed ID: 8639494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity.
    Lesburg CA; Huang C; Christianson DW; Fierke CA
    Biochemistry; 1997 Dec; 36(50):15780-91. PubMed ID: 9398308
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional characterization of human carbonic anhydrase II variants with altered zinc binding sites.
    Kiefer LL; Fierke CA
    Biochemistry; 1994 Dec; 33(51):15233-40. PubMed ID: 7803385
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional consequences of engineering the hydrophobic pocket of carbonic anhydrase II.
    Fierke CA; Calderone TL; Krebs JF
    Biochemistry; 1991 Nov; 30(46):11054-63. PubMed ID: 1657158
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
    Duda D; Tu C; Qian M; Laipis P; Agbandje-McKenna M; Silverman DN; McKenna R
    Biochemistry; 2001 Feb; 40(6):1741-8. PubMed ID: 11327835
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering the zinc binding site of human carbonic anhydrase II: structure of the His-94-->Cys apoenzyme in a new crystalline form.
    Alexander RS; Kiefer LL; Fierke CA; Christianson DW
    Biochemistry; 1993 Feb; 32(6):1510-8. PubMed ID: 8431430
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121.
    Nair SK; Calderone TL; Christianson DW; Fierke CA
    J Biol Chem; 1991 Sep; 266(26):17320-5. PubMed ID: 1910042
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II.
    Nair SK; Christianson DW
    Biochemistry; 1993 May; 32(17):4506-14. PubMed ID: 8485129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural consequences of redesigning a protein-zinc binding site.
    Ippolito JA; Christianson DW
    Biochemistry; 1994 Dec; 33(51):15241-9. PubMed ID: 7803386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-assisted redesign of a protein-zinc-binding site with femtomolar affinity.
    Ippolito JA; Baird TT; McGee SA; Christianson DW; Fierke CA
    Proc Natl Acad Sci U S A; 1995 May; 92(11):5017-21. PubMed ID: 7761440
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinetic and spectroscopic studies of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II.
    Krebs JF; Rana F; Dluhy RA; Fierke CA
    Biochemistry; 1993 May; 32(17):4496-505. PubMed ID: 8485128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystallographic analysis of Thr-200-->His human carbonic anhydrase II and its complex with the substrate, HCO3-.
    Xue Y; Vidgren J; Svensson LA; Liljas A; Jonsson BH; Lindskog S
    Proteins; 1993 Jan; 15(1):80-7. PubMed ID: 8451242
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proton transfer by histidine 67 in site-directed mutants of human carbonic anhydrase III.
    Ren X; Tu C; Laipis PJ; Silverman DN
    Biochemistry; 1995 Jul; 34(26):8492-8. PubMed ID: 7599138
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural properties of human carbonic anhydrase II at pH 9.5.
    Nair SK; Christianson DW
    Biochem Biophys Res Commun; 1991 Dec; 181(2):579-84. PubMed ID: 1755840
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V.
    Heck RW; Boriack-Sjodin PA; Qian M; Tu C; Christianson DW; Laipis PJ; Silverman DN
    Biochemistry; 1996 Sep; 35(36):11605-11. PubMed ID: 8794740
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
    Xue Y; Liljas A; Jonsson BH; Lindskog S
    Proteins; 1993 Sep; 17(1):93-106. PubMed ID: 7901850
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.
    Boriack-Sjodin PA; Heck RW; Laipis PJ; Silverman DN; Christianson DW
    Proc Natl Acad Sci U S A; 1995 Nov; 92(24):10949-53. PubMed ID: 7479916
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
    Cox JD; Hunt JA; Compher KM; Fierke CA; Christianson DW
    Biochemistry; 2000 Nov; 39(45):13687-94. PubMed ID: 11076507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.
    Fisher Z; Hernandez Prada JA; Tu C; Duda D; Yoshioka C; An H; Govindasamy L; Silverman DN; McKenna R
    Biochemistry; 2005 Feb; 44(4):1097-105. PubMed ID: 15667203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.