BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 19099450)

  • 1. Camptothecins: a SAR/QSAR study.
    Verma RP; Hansch C
    Chem Rev; 2009 Jan; 109(1):213-35. PubMed ID: 19099450
    [No Abstract]   [Full Text] [Related]  

  • 2. Synthesis and biological evaluation of 10,11-methylenedioxy-14-azacamptothecin.
    Elban MA; Sun W; Eisenhauer BM; Gao R; Hecht SM
    Org Lett; 2006 Aug; 8(16):3513-6. PubMed ID: 16869648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of E-ring modifications in camptothecin on topoisomerase I inhibition: a quantum mechanics treatment.
    Xiao X; Cushman M
    J Org Chem; 2005 Nov; 70(23):9584-7. PubMed ID: 16268636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it?
    Jung LL; Zamboni WC
    Drug Resist Updat; 2001 Aug; 4(4):273-88. PubMed ID: 11998845
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and cytotoxic activity of new 9-substituted camptothecins.
    Dallavalle S; Rocchetta DG; Musso L; Merlini L; Morini G; Penco S; Tinelli S; Beretta GL; Zunino F
    Bioorg Med Chem Lett; 2008 May; 18(9):2781-7. PubMed ID: 18434153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 7- and 10-substituted camptothecins: dependence of topoisomerase I-DNA cleavable complex formation and stability on the 7- and 10-substituents.
    Vladu B; Woynarowski JM; Manikumar G; Wani MC; Wall ME; Von Hoff DD; Wadkins RM
    Mol Pharmacol; 2000 Feb; 57(2):243-51. PubMed ID: 10648633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Synthesis of camptothecin glycosides by phase transfer-catalysis and its inhibitory activity against topo I].
    Li QY; Zhang Y; Yao LP; Fu YJ; Zu YG; Chen XQ; Zheng CY
    Yao Xue Xue Bao; 2005 Dec; 40(12):1116-21. PubMed ID: 16496676
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Current status of camptothecin derivatives as natural antitumor agents].
    Pan XD; Wang CY
    Yao Xue Xue Bao; 2003 Sep; 38(9):715-20. PubMed ID: 14730926
    [No Abstract]   [Full Text] [Related]  

  • 9. Role of flexibility and long range communication on the function of human topoisomerase I.
    Chillemi G; Fiorani P; Bruselles A; Castelli S; Campagna A; Sarra O; Tesauro C; Fiorentini M; Vassallo O; D'Annessa I; Santoleri S; Desideri A
    Ital J Biochem; 2007 Jun; 56(2):110-4. PubMed ID: 17722651
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Semi-synthesis and biological activity of gamma-lactones analogs of camptothecin.
    Li M; Tang W; Zeng F; Lou L; You T
    Bioorg Med Chem Lett; 2008 Dec; 18(24):6441-3. PubMed ID: 18986807
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins.
    Garcia-Carbonero R; Supko JG
    Clin Cancer Res; 2002 Mar; 8(3):641-61. PubMed ID: 11895891
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and anti-tumor activity of alkenyl camptothecin esters.
    Cao ZS; Mendoza J; Dejesus A; Giovanella B
    Acta Pharmacol Sin; 2005 Feb; 26(2):235-41. PubMed ID: 15663905
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A tale of two tumor targets: topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy.
    Cragg GM; Newman DJ
    J Nat Prod; 2004 Feb; 67(2):232-44. PubMed ID: 14987065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Inhibitors of DNA topoisomerases].
    Andoh T
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1526-35. PubMed ID: 9309151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it?
    Jung LL; Zamboni WC
    Drug Resist Updat; 2001 Jun; 4(3):152-67. PubMed ID: 11768329
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 20-(S)-camptothecin analogues as DNA topoisomerase I inhibitors: a QSAR study.
    Hansch C; Verma RP
    ChemMedChem; 2007 Dec; 2(12):1807-13. PubMed ID: 17886246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Persistence of camptothecin analog-topoisomerase I-DNA ternary complexes: a molecular dynamics study.
    Siu FM; Che CM
    J Am Chem Soc; 2008 Dec; 130(52):17928-37. PubMed ID: 19035632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.
    Borges-Argáez R; Balnbury L; Flowers A; Giménez-Turba A; Ruiz G; Waterman PG; Peña-Rodríguez LM
    Phytomedicine; 2007 Aug; 14(7-8):530-3. PubMed ID: 17291734
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.
    Samorì C; Guerrini A; Varchi G; Fontana G; Bombardelli E; Tinelli S; Beretta GL; Basili S; Moro S; Zunino F; Battaglia A
    J Med Chem; 2009 Feb; 52(4):1029-39. PubMed ID: 19530720
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Understanding topoisomerase I and II in terms of QSAR.
    Verma RP
    Bioorg Med Chem; 2005 Feb; 13(4):1059-67. PubMed ID: 15670914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.