516 related articles for article (PubMed ID: 19100337)
1. The future of drug safety testing: expanding the view and narrowing the focus.
Stevens JL; Baker TK
Drug Discov Today; 2009 Feb; 14(3-4):162-7. PubMed ID: 19100337
[TBL] [Abstract][Full Text] [Related]
2. The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates.
Kramer JA; Sagartz JE; Morris DL
Nat Rev Drug Discov; 2007 Aug; 6(8):636-49. PubMed ID: 17643090
[TBL] [Abstract][Full Text] [Related]
3. The state-of-the-art in predictive toxicogenomics.
Fielden MR; Kolaja KL
Curr Opin Drug Discov Devel; 2006 Jan; 9(1):84-91. PubMed ID: 16445120
[TBL] [Abstract][Full Text] [Related]
4. Future of toxicology--mechanisms of toxicity and drug safety: where do we go from here?
Stevens JL
Chem Res Toxicol; 2006 Nov; 19(11):1393-401. PubMed ID: 17112225
[TBL] [Abstract][Full Text] [Related]
5. Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development.
Whitebread S; Hamon J; Bojanic D; Urban L
Drug Discov Today; 2005 Nov; 10(21):1421-33. PubMed ID: 16243262
[TBL] [Abstract][Full Text] [Related]
6. Toxicogenomics in drug discovery: from preclinical studies to clinical trials.
Yang Y; Blomme EA; Waring JF
Chem Biol Interact; 2004 Nov; 150(1):71-85. PubMed ID: 15522262
[TBL] [Abstract][Full Text] [Related]
7. New technologies and screening strategies for hepatotoxicity: use of in vitro models.
Dambach DM; Andrews BA; Moulin F
Toxicol Pathol; 2005; 33(1):17-26. PubMed ID: 15805052
[TBL] [Abstract][Full Text] [Related]
8. The timing of preclinical toxicological studies: pharmaceutical company approaches to toxicity testing in support of initial clinical investigations.
Parkinson C; Thomas KE; Lumley CE
Regul Toxicol Pharmacol; 1996 Apr; 23(2):162-72. PubMed ID: 8661335
[TBL] [Abstract][Full Text] [Related]
9. Safety evaluation to support First-In-Man investigations II: toxicology studies.
Baldrick P
Regul Toxicol Pharmacol; 2008 Jul; 51(2):237-43. PubMed ID: 18501490
[TBL] [Abstract][Full Text] [Related]
10. [The safety of drugs].
de Cea Lavech de Chancy H
Rev Clin Esp; 1990 Sep; 187(4):184-90. PubMed ID: 2091076
[TBL] [Abstract][Full Text] [Related]
11. Short patent lives jeopardize drug and patient safety.
Hondeghem LM; De Clerck F; Camm J
J Cardiovasc Pharmacol; 2007 Oct; 50(4):353-7. PubMed ID: 18049301
[TBL] [Abstract][Full Text] [Related]
12. Less is more: the human microdosing concept.
Garner RC
Drug Discov Today; 2005 Apr; 10(7):449-51. PubMed ID: 15809185
[No Abstract] [Full Text] [Related]
13. Optimising the design of preliminary toxicity studies for pharmaceutical safety testing in the dog.
Smith D; Combes R; Depelchin O; Jacobsen SD; Hack R; Luft J; Lammens L; von Landenberg F; Phillips B; Pfister R; Rabemampianina Y; Sparrow S; Stark C; Stephan-Gueldner M
Regul Toxicol Pharmacol; 2005 Mar; 41(2):95-101. PubMed ID: 15698532
[TBL] [Abstract][Full Text] [Related]
14. How omics technologies can contribute to the '3R' principles by introducing new strategies in animal testing.
Kroeger M
Trends Biotechnol; 2006 Aug; 24(8):343-6. PubMed ID: 16782220
[TBL] [Abstract][Full Text] [Related]
15. Safety in clinical trials.
Wallander MA
Scand J Prim Health Care Suppl; 1990; 1():89-91. PubMed ID: 2100372
[TBL] [Abstract][Full Text] [Related]
16. Interpretation and considerations on the safety evaluation of human drug metabolites.
Atrakchi AH
Chem Res Toxicol; 2009 Jul; 22(7):1217-20. PubMed ID: 19563206
[TBL] [Abstract][Full Text] [Related]
17. Toxicity testing in the 21st century: a view from the pharmaceutical industry.
MacDonald JS; Robertson RT
Toxicol Sci; 2009 Jul; 110(1):40-6. PubMed ID: 19435982
[No Abstract] [Full Text] [Related]
18. Introduction: Human metabolites in safety testing (MIST) issue.
Guengerich FP
Chem Res Toxicol; 2009 Feb; 22(2):237-8. PubMed ID: 19216576
[No Abstract] [Full Text] [Related]
19. Preclinical predictors of clinical safety: opportunities for improvement.
Sistare FD; DeGeorge JJ
Clin Pharmacol Ther; 2007 Aug; 82(2):210-4. PubMed ID: 17507920
[TBL] [Abstract][Full Text] [Related]
20. [Safety assessment of new products developed by the pharmaceutical industry].
Claude JR
Ann Pharm Fr; 2001 Sep; 59(5):324-30. PubMed ID: 11787426
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
