BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 19103484)

  • 1. Matched molecular pair analysis of activity and properties of glycogen phosphorylase inhibitors.
    Birch AM; Kenny PW; Simpson I; Whittamore PR
    Bioorg Med Chem Lett; 2009 Feb; 19(3):850-3. PubMed ID: 19103484
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups.
    Sparks SM; Banker P; Bickett DM; Carter HL; Clancy DC; Dickerson SH; Dwornik KA; Garrido DM; Golden PL; Nolte RT; Peat AJ; Sheckler LR; Tavares FX; Thomson SA; Wang L; Weiel JE
    Bioorg Med Chem Lett; 2009 Feb; 19(3):976-80. PubMed ID: 19095442
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L; Li H; Liu J; Zhang L; Liu H; Jiang H
    Bioorg Med Chem; 2007 Nov; 15(21):6763-74. PubMed ID: 17719791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG; Somsák L
    Curr Opin Investig Drugs; 2008 Apr; 9(4):379-95. PubMed ID: 18393105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues.
    Sparks SM; Banker P; Bickett DM; Clancy DC; Dickerson SH; Garrido DM; Golden PL; Peat AJ; Sheckler LR; Tavares FX; Thomson SA; Weiel JE
    Bioorg Med Chem Lett; 2009 Feb; 19(3):981-5. PubMed ID: 19095443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel design principle validated: glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent.
    Somsák L; Nagy V; Vidal S; Czifrák K; Berzsényi E; Praly JP
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5680-3. PubMed ID: 18793852
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modeling aided design of potent glycogen phosphorylase inhibitors.
    Deng Q; Lu Z; Bohn J; Ellsworth KP; Myers RW; Geissler WM; Harris G; Willoughby CA; Chapman K; McKeever B; Mosley R
    J Mol Graph Model; 2005 Apr; 23(5):457-64. PubMed ID: 15781188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads.
    Habash M; Taha MO
    Bioorg Med Chem; 2011 Aug; 19(16):4746-71. PubMed ID: 21788139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New inhibitors of glycogen phosphorylase as potential antidiabetic agents.
    Somsák L; Czifrák K; Tóth M; Bokor E; Chrysina ED; Alexacou KM; Hayes JM; Tiraidis C; Lazoura E; Leonidas DD; Zographos SE; Oikonomakos NG
    Curr Med Chem; 2008; 15(28):2933-83. PubMed ID: 19075645
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Zhu P; Bi Y; Xu J; Li Z; Liu J; Zhang L; Ye W; Wu X
    Bioorg Med Chem Lett; 2009 Dec; 19(24):6966-9. PubMed ID: 19889536
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantitative structure-based design: formalism and application of receptor-dependent RD-4D-QSAR analysis to a set of glucose analogue inhibitors of glycogen phosphorylase.
    Pan D; Tseng Y; Hopfinger AJ
    J Chem Inf Comput Sci; 2003; 43(5):1591-607. PubMed ID: 14502494
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New pentacyclic triterpenes from Gypsophila oldhamiana and their biological evaluation as glycogen phosphorylase inhibitors.
    Luo JG; Liu J; Kong LY
    Chem Biodivers; 2008 May; 5(5):751-7. PubMed ID: 18493961
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationships of 3-phenyl-2-propenamides as inhibitors of glycogen phosphorylase a.
    Li YH; Coppo FT; Evans KA; Graybill TL; Patel M; Gale J; Li H; Tavares F; Thomson SA
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5892-6. PubMed ID: 16942879
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).
    Moriarty KJ; Takahashi H; Pullen SS; Khine HH; Sallati RH; Raymond EL; Woska JR; Jeanfavre DD; Roth GP; Winters MP; Qiao L; Ryan D; DesJarlais R; Robinson D; Wilson M; Bobko M; Cook BN; Lo HY; Nemoto PA; Kashem MA; Wolak JP; White A; Magolda RL; Tomczuk B
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5545-9. PubMed ID: 18819799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-
    Fischer T; Koulas SM; Tsagkarakou AS; Kyriakis E; Stravodimos GA; Skamnaki VT; Liggri PGV; Zographos SE; Riedl R; Leonidas DD
    Molecules; 2019 Apr; 24(7):. PubMed ID: 30987252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors.
    Evans KA; Li YH; Coppo FT; Graybill TL; Cichy-Knight M; Patel M; Gale J; Li H; Thrall SH; Tew D; Tavares F; Thomson SA; Weiel JE; Boucheron JA; Clancy DC; Epperly AH; Golden PL
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4068-71. PubMed ID: 18554908
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of glucose on the potency of two distinct glycogen phosphorylase inhibitors.
    Andersen B; Westergaard N
    Biochem J; 2002 Oct; 367(Pt 2):443-50. PubMed ID: 12099891
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of oleanolic acid dimers as inhibitors of glycogen phosphorylase.
    Cheng K; Liu J; Sun H; Xie J
    Chem Biodivers; 2010 Mar; 7(3):690-7. PubMed ID: 20232331
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trithiocarbonates: exploration of a new head group for HDAC inhibitors.
    Dehmel F; Ciossek T; Maier T; Weinbrenner S; Schmidt B; Zoche M; Beckers T
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4746-52. PubMed ID: 17606370
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
    Onda K; Shiraki R; Ogiyama T; Yokoyama K; Momose K; Katayama N; Orita M; Yamaguchi T; Furutani M; Hamada N; Takeuchi M; Okada M; Ohta M; Tsukamoto S
    Bioorg Med Chem; 2008 Dec; 16(23):10001-12. PubMed ID: 18952447
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.