BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 19112020)

  • 1. New potential inhibitors of DNA topoisomerase. Part II: Design and synthesis of alpha-lapachone derivatives under microwave irradiation.
    Wei P; Zhang X; Tu S; Yan S; Ying H; Ouyang P
    Bioorg Med Chem Lett; 2009 Feb; 19(3):828-30. PubMed ID: 19112020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and topoisomerase poisoning activity of A-ring and E-ring substituted luotonin A derivatives.
    Nacro K; Zha CC; Guzzo PR; Jason Herr R; Peace D; Friedrich TD
    Bioorg Med Chem; 2007 Jun; 15(12):4237-46. PubMed ID: 17418582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, docking, and synthesis of novel indeno[1,2-c]isoquinolines for the development of antitumor agents as topoisomerase I inhibitors.
    Cho WJ; Le QM; My Van HT; Youl Lee K; Kang BY; Lee ES; Lee SK; Kwon Y
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3531-4. PubMed ID: 17498951
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 20-(S)-camptothecin analogues as DNA topoisomerase I inhibitors: a QSAR study.
    Hansch C; Verma RP
    ChemMedChem; 2007 Dec; 2(12):1807-13. PubMed ID: 17886246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The design, synthesis, and evaluation of two universal doxorubicin-linkers: preparation of conjugates that retain topoisomerase II activity.
    Sun C; Aspland SE; Ballatore C; Castillo R; Smith AB; Castellino AJ
    Bioorg Med Chem Lett; 2006 Jan; 16(1):104-7. PubMed ID: 16242325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumour drug design: DNA-binding ligands, which inhibit the topoisomerase I.
    Pindur U; Lemster T
    Pharmazie; 1998 Feb; 53(2):79-86. PubMed ID: 9540103
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural modification of 3-arylisoquinolines to isoindolo[2,1-b]isoquinolinones for the development of novel topoisomerase 1 inhibitors with molecular docking study.
    Van HT; Cho WJ
    Bioorg Med Chem Lett; 2009 May; 19(9):2551-4. PubMed ID: 19328687
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors.
    Lee SH; Van HT; Yang SH; Lee KT; Kwon Y; Cho WJ
    Bioorg Med Chem Lett; 2009 May; 19(9):2444-7. PubMed ID: 19345580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microwave-assisted synthesis of unnatural amino acids.
    Young DD; Torres-Kolbus J; Deiters A
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5478-80. PubMed ID: 18809329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.
    Cho HJ; Jung MJ; Kwon Y; Na Y
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6766-9. PubMed ID: 19836231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity.
    Spicer JA; Finlay GJ; Baguley BC; Velea L; Graves DE; Denny WA
    Anticancer Drug Des; 1999 Feb; 14(1):37-45. PubMed ID: 10363026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.
    Dallavalle S; Gattinoni S; Mazzini S; Scaglioni L; Merlini L; Tinelli S; Beretta GL; Zunino F
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1484-9. PubMed ID: 18248813
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids.
    Fox BM; Xiao X; Antony S; Kohlhagen G; Pommier Y; Staker BL; Stewart L; Cushman M
    J Med Chem; 2003 Jul; 46(15):3275-82. PubMed ID: 12852757
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cationic porphyrins and analogues as new DNA topoisomerase I and II inhibitors.
    Shuai L; Wang S; Zhang L; Fu B; Zhou X
    Chem Biodivers; 2009 Jun; 6(6):827-37. PubMed ID: 19551725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. L-proline analogues of anthraquinone-2-carboxylic acid: cytotoxic activity in breast cancer MCF-7 cells and inhibitory activity against topoisomerase I and II.
    Bielawska A; Kosk K; Bielawski K
    Pol J Pharmacol; 2001; 53(3):283-7. PubMed ID: 11785929
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of cytotoxic 11-aminoalkenylindenoisoquinoline and 11-diaminoalkenylindenoisoquinoline topoisomerase I inhibitors.
    Xiao X; Antony S; Kohlhagen G; Pommier Y; Cushman M
    Bioorg Med Chem; 2004 Oct; 12(19):5147-60. PubMed ID: 15351398
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antitumor properties of N-[2-(dimethylamino)ethyl]carboxamide derivatives of fused tetracyclic quinolines and quinoxalines: a new class of putative topoisomerase inhibitors.
    Deady LW; Kaye AJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(13):2040-6. PubMed ID: 9207945
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Facile synthesis of new 4-aza-podophyllotoxin analogs via microwave-assisted multi-component reactions and evaluation of their cytotoxic activity.
    Shi F; Zeng XN; Zhang G; Ma N; Jiang B; Tu S
    Bioorg Med Chem Lett; 2011 Dec; 21(23):7119-23. PubMed ID: 22004717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of analogues of the anti-tumor alkaloid naamidine A.
    Aberle N; Catimel J; Nice EC; Watson KG
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3741-4. PubMed ID: 17462892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disulfiram is a potent in vitro inhibitor of DNA topoisomerases.
    Yakisich JS; Sidén A; Eneroth P; Cruz M
    Biochem Biophys Res Commun; 2001 Nov; 289(2):586-90. PubMed ID: 11716515
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.