BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 19114656)

  • 1. A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.
    Rahdar M; Inoue T; Meyer T; Zhang J; Vazquez F; Devreotes PN
    Proc Natl Acad Sci U S A; 2009 Jan; 106(2):480-5. PubMed ID: 19114656
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular Features of Phosphatase and Tensin Homolog (PTEN) Regulation by C-terminal Phosphorylation.
    Chen Z; Dempsey DR; Thomas SN; Hayward D; Bolduc DM; Cole PA
    J Biol Chem; 2016 Jul; 291(27):14160-14169. PubMed ID: 27226612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.
    Nguyen HN; Afkari Y; Senoo H; Sesaki H; Devreotes PN; Iijima M
    Oncogene; 2014 Dec; 33(50):5688-96. PubMed ID: 24292679
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mutant form of PTEN linked to autism.
    Redfern RE; Daou MC; Li L; Munson M; Gericke A; Ross AH
    Protein Sci; 2010 Oct; 19(10):1948-56. PubMed ID: 20718038
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate.
    Chia YC; Catimel B; Lio DS; Ang CS; Peng B; Wu H; Zhu HJ; Cheng HC
    Arch Biochem Biophys; 2015 Dec; 587():48-60. PubMed ID: 26471078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphate.
    Campbell RB; Liu F; Ross AH
    J Biol Chem; 2003 Sep; 278(36):33617-20. PubMed ID: 12857747
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer.
    Malaney P; Palumbo E; Semidey-Hurtado J; Hardee J; Stanford K; Kathiriya JJ; Patel D; Tian Z; Allen-Gipson D; Davé V
    Cell Cycle; 2018; 17(8):947-962. PubMed ID: 29108454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.
    Johnston SB; Raines RT
    PLoS One; 2015; 10(1):e0116898. PubMed ID: 25607987
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interactions of phosphatase and tensin homologue (PTEN) proteins with phosphatidylinositol phosphates: insights from molecular dynamics simulations of PTEN and voltage sensitive phosphatase.
    Kalli AC; Devaney I; Sansom MS
    Biochemistry; 2014 Mar; 53(11):1724-32. PubMed ID: 24588644
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane.
    Huang J; Yan J; Zhang J; Zhu S; Wang Y; Shi T; Zhu C; Chen C; Liu X; Cheng J; Mustelin T; Feng GS; Chen G; Yu J
    Nat Commun; 2012 Jun; 3():911. PubMed ID: 22713753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane.
    Vazquez F; Matsuoka S; Sellers WR; Yanagida T; Ueda M; Devreotes PN
    Proc Natl Acad Sci U S A; 2006 Mar; 103(10):3633-8. PubMed ID: 16537447
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane-binding and activation mechanism of PTEN.
    Das S; Dixon JE; Cho W
    Proc Natl Acad Sci U S A; 2003 Jun; 100(13):7491-6. PubMed ID: 12808147
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.
    Walker SM; Leslie NR; Perera NM; Batty IH; Downes CP
    Biochem J; 2004 Apr; 379(Pt 2):301-7. PubMed ID: 14711368
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Understanding PTEN regulation: PIP2, polarity and protein stability.
    Leslie NR; Batty IH; Maccario H; Davidson L; Downes CP
    Oncogene; 2008 Sep; 27(41):5464-76. PubMed ID: 18794881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitination of PTEN (phosphatase and tensin homolog) inhibits phosphatase activity and is enhanced by membrane targeting and hyperosmotic stress.
    Maccario H; Perera NM; Gray A; Downes CP; Leslie NR
    J Biol Chem; 2010 Apr; 285(17):12620-8. PubMed ID: 20177066
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate.
    Iwasaki H; Murata Y; Kim Y; Hossain MI; Worby CA; Dixon JE; McCormack T; Sasaki T; Okamura Y
    Proc Natl Acad Sci U S A; 2008 Jun; 105(23):7970-5. PubMed ID: 18524949
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defining the membrane-associated state of the PTEN tumor suppressor protein.
    Lumb CN; Sansom MS
    Biophys J; 2013 Feb; 104(3):613-21. PubMed ID: 23442912
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase.
    Chagpar RB; Links PH; Pastor MC; Furber LA; Hawrysh AD; Chamberlain MD; Anderson DH
    Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5471-6. PubMed ID: 20212113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTEN M-CBR3, a versatile and selective regulator of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Evidence for Ins(1,3,4,5,6)P5 as a proliferative signal.
    Orchiston EA; Bennett D; Leslie NR; Clarke RG; Winward L; Downes CP; Safrany ST
    J Biol Chem; 2004 Jan; 279(2):1116-22. PubMed ID: 14561749
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear localization of PTEN is regulated by Ca(2+) through a tyrosil phosphorylation-independent conformational modification in major vault protein.
    Minaguchi T; Waite KA; Eng C
    Cancer Res; 2006 Dec; 66(24):11677-82. PubMed ID: 17178862
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.