288 related articles for article (PubMed ID: 19114711)
1. Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis.
Martin L; Fluhrer R; Haass C
J Biol Chem; 2009 Feb; 284(9):5662-70. PubMed ID: 19114711
[TBL] [Abstract][Full Text] [Related]
2. The α-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b).
Fluhrer R; Martin L; Klier B; Haug-Kröper M; Grammer G; Nuscher B; Haass C
J Biol Chem; 2012 Feb; 287(7):5156-63. PubMed ID: 22194595
[TBL] [Abstract][Full Text] [Related]
3. Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
Martin L; Fluhrer R; Reiss K; Kremmer E; Saftig P; Haass C
J Biol Chem; 2008 Jan; 283(3):1644-1652. PubMed ID: 17965014
[TBL] [Abstract][Full Text] [Related]
4. Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
Fleck D; Voss M; Brankatschk B; Giudici C; Hampel H; Schwenk B; Edbauer D; Fukumori A; Steiner H; Kremmer E; Haug-Kröper M; Rossner MJ; Fluhrer R; Willem M; Haass C
J Biol Chem; 2016 Jan; 291(1):318-33. PubMed ID: 26574544
[TBL] [Abstract][Full Text] [Related]
5. Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
Brady OA; Zhou X; Hu F
J Biol Chem; 2014 Jul; 289(28):19670-80. PubMed ID: 24872421
[TBL] [Abstract][Full Text] [Related]
6. Physiological functions of SPP/SPPL intramembrane proteases.
Mentrup T; Cabrera-Cabrera F; Fluhrer R; Schröder B
Cell Mol Life Sci; 2020 Aug; 77(15):2959-2979. PubMed ID: 32052089
[TBL] [Abstract][Full Text] [Related]
7. Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
Mentrup T; Loock AC; Fluhrer R; Schröder B
Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2169-2182. PubMed ID: 28624439
[TBL] [Abstract][Full Text] [Related]
8. Foamy virus envelope protein is a substrate for signal peptide peptidase-like 3 (SPPL3).
Voss M; Fukumori A; Kuhn PH; Künzel U; Klier B; Grammer G; Haug-Kröper M; Kremmer E; Lichtenthaler SF; Steiner H; Schröder B; Haass C; Fluhrer R
J Biol Chem; 2012 Dec; 287(52):43401-9. PubMed ID: 23132852
[TBL] [Abstract][Full Text] [Related]
9. The role of SPP/SPPL intramembrane proteases in membrane protein homeostasis.
Mentrup T; Leinung N; Patel M; Fluhrer R; Schröder B
FEBS J; 2024 Jan; 291(1):25-44. PubMed ID: 37625440
[TBL] [Abstract][Full Text] [Related]
10. A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.
Fluhrer R; Grammer G; Israel L; Condron MM; Haffner C; Friedmann E; Böhland C; Imhof A; Martoglio B; Teplow DB; Haass C
Nat Cell Biol; 2006 Aug; 8(8):894-6. PubMed ID: 16829951
[TBL] [Abstract][Full Text] [Related]
11. Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases.
Voss M; Schröder B; Fluhrer R
Biochim Biophys Acta; 2013 Dec; 1828(12):2828-39. PubMed ID: 24099004
[TBL] [Abstract][Full Text] [Related]
12. Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.
Hogl S; Kuhn PH; Colombo A; Lichtenthaler SF
PLoS One; 2011; 6(6):e21337. PubMed ID: 21695060
[TBL] [Abstract][Full Text] [Related]
13. The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).
Houri N; Huang KC; Nalbantoglu J
PLoS One; 2013; 8(8):e73296. PubMed ID: 24015300
[TBL] [Abstract][Full Text] [Related]
14. Klotho is a substrate for alpha-, beta- and gamma-secretase.
Bloch L; Sineshchekova O; Reichenbach D; Reiss K; Saftig P; Kuro-o M; Kaether C
FEBS Lett; 2009 Oct; 583(19):3221-4. PubMed ID: 19737556
[TBL] [Abstract][Full Text] [Related]
15. The intramembrane proteases SPPL2a and SPPL2b regulate the homeostasis of selected SNARE proteins.
Ballin M; Griep W; Patel M; Karl M; Mentrup T; Rivera-Monroy J; Foo B; Schwappach B; Schröder B
FEBS J; 2023 May; 290(9):2320-2337. PubMed ID: 36047592
[TBL] [Abstract][Full Text] [Related]
16. Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74.
Hüttl S; Helfrich F; Mentrup T; Held S; Fukumori A; Steiner H; Saftig P; Fluhrer R; Schröder B
Biochem J; 2016 May; 473(10):1405-22. PubMed ID: 26987812
[TBL] [Abstract][Full Text] [Related]
17. Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.
Fluhrer R; Fukumori A; Martin L; Grammer G; Haug-Kröper M; Klier B; Winkler E; Kremmer E; Condron MM; Teplow DB; Steiner H; Haass C
J Biol Chem; 2008 Oct; 283(44):30121-8. PubMed ID: 18768471
[TBL] [Abstract][Full Text] [Related]
18. Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3.
Krawitz P; Haffner C; Fluhrer R; Steiner H; Schmid B; Haass C
J Biol Chem; 2005 Nov; 280(47):39515-23. PubMed ID: 15998642
[TBL] [Abstract][Full Text] [Related]
19. Latest emerging functions of SPP/SPPL intramembrane proteases.
Mentrup T; Fluhrer R; Schröder B
Eur J Cell Biol; 2017 Aug; 96(5):372-382. PubMed ID: 28366434
[TBL] [Abstract][Full Text] [Related]
20. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors.
Ran Y; Ladd GZ; Ceballos-Diaz C; Jung JI; Greenbaum D; Felsenstein KM; Golde TE
PLoS One; 2015; 10(6):e0128619. PubMed ID: 26046535
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]