74 related articles for article (PubMed ID: 19117542)
1. Structure of full-length PPARgamma-RXRalpha: a snapshot of a functional complex?
Moras D
Cell Metab; 2009 Jan; 9(1):8-10. PubMed ID: 19117542
[TBL] [Abstract][Full Text] [Related]
2. Manipulation of reciprocal salt bridges at the heterodimerization interface alters the dimerization properties of mouse RXRalpha and PPARgamma1.
Chan LS; Wells RA
Biochem Biophys Res Commun; 2007 Jul; 358(4):1080-5. PubMed ID: 17521607
[TBL] [Abstract][Full Text] [Related]
3. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands.
Waku T; Shiraki T; Oyama T; Morikawa K
FEBS Lett; 2009 Jan; 583(2):320-4. PubMed ID: 19101554
[TBL] [Abstract][Full Text] [Related]
4. Heme-binding to the nuclear receptor retinoid X receptor alpha (RXRalpha) leads to the inhibition of the transcriptional activity.
Gotoh S; Ohgari Y; Nakamura T; Osumi T; Taketani S
Gene; 2008 Nov; 423(2):207-14. PubMed ID: 18675890
[TBL] [Abstract][Full Text] [Related]
5. Molecular determinants of magnolol targeting both RXRα and PPARγ.
Zhang H; Xu X; Chen L; Chen J; Hu L; Jiang H; Shen X
PLoS One; 2011; 6(11):e28253. PubMed ID: 22140563
[TBL] [Abstract][Full Text] [Related]
6. Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex.
Ricci CG; Silveira RL; Rivalta I; Batista VS; Skaf MS
Sci Rep; 2016 Jan; 6():19940. PubMed ID: 26823026
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex.
Lemkul JA; Lewis SN; Bassaganya-Riera J; Bevan DR
PLoS One; 2015; 10(5):e0123984. PubMed ID: 25954810
[TBL] [Abstract][Full Text] [Related]
8. Protein polarization is critical to stabilizing AF-2 and helix-2' domains in ligand binding to PPAR-gamma.
Ji CG; Zhang JZ
J Am Chem Soc; 2008 Dec; 130(50):17129-33. PubMed ID: 19007119
[TBL] [Abstract][Full Text] [Related]
9. Functional implications of genetic variation in human PPARgamma.
Jeninga EH; Gurnell M; Kalkhoven E
Trends Endocrinol Metab; 2009 Oct; 20(8):380-7. PubMed ID: 19748282
[TBL] [Abstract][Full Text] [Related]
10. Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Chandra V; Huang P; Hamuro Y; Raghuram S; Wang Y; Burris TP; Rastinejad F
Nature; 2008 Nov; 456(7220):350-6. PubMed ID: 19043829
[TBL] [Abstract][Full Text] [Related]
11. Low-resolution molecular models reveal the oligomeric state of the PPAR and the conformational organization of its domains in solution.
Bernardes A; Batista FA; de Oliveira Neto M; Figueira AC; Webb P; Saidemberg D; Palma MS; Polikarpov I
PLoS One; 2012; 7(2):e31852. PubMed ID: 22363753
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of benzofused heterocyclic RXR modulators.
Gernert DL; Neel DA; Boehm MF; Leibowitz MD; Mais DA; Michellys PY; Rungta D; Reifel-Miller A; Grese TA
Bioorg Med Chem Lett; 2004 Jun; 14(11):2759-63. PubMed ID: 15125928
[TBL] [Abstract][Full Text] [Related]
13. The effect of antagonists on the conformational exchange of the retinoid X receptor alpha ligand-binding domain.
Lu J; Dawson MI; Hu QY; Xia Z; Dambacher JD; Ye M; Zhang XK; Li E
Magn Reson Chem; 2009 Dec; 47(12):1071-80. PubMed ID: 19757405
[TBL] [Abstract][Full Text] [Related]
14. Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα.
Wallace BD; Betts L; Talmage G; Pollet RM; Holman NS; Redinbo MR
J Mol Biol; 2013 Jul; 425(14):2561-77. PubMed ID: 23602807
[TBL] [Abstract][Full Text] [Related]
15. Structure-based de novo design, synthesis, and biological evaluation of the indole-based PPARgamma ligands (I).
Dong X; Zhang Z; Wen R; Shen J; Shen X; Jiang H
Bioorg Med Chem Lett; 2006 Nov; 16(22):5913-6. PubMed ID: 17010604
[TBL] [Abstract][Full Text] [Related]
16. Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Korpal M; Puyang X; Jeremy Wu Z; Seiler R; Furman C; Oo HZ; Seiler M; Irwin S; Subramanian V; Julie Joshi J; Wang CK; Rimkunas V; Tortora D; Yang H; Kumar N; Kuznetsov G; Matijevic M; Chow J; Kumar P; Zou J; Feala J; Corson L; Henry R; Selvaraj A; Davis A; Bloudoff K; Douglas J; Kiss B; Roberts M; Fazli L; Black PC; Fekkes P; Smith PG; Warmuth M; Yu L; Hao MH; Larsen N; Daugaard M; Zhu P
Nat Commun; 2017 Jul; 8(1):103. PubMed ID: 28740126
[TBL] [Abstract][Full Text] [Related]
17. Recurrent activating mutations of PPARγ associated with luminal bladder tumors.
Rochel N; Krucker C; Coutos-Thévenot L; Osz J; Zhang R; Guyon E; Zita W; Vanthong S; Hernandez OA; Bourguet M; Badawy KA; Dufour F; Peluso-Iltis C; Heckler-Beji S; Dejaegere A; Kamoun A; de Reyniès A; Neuzillet Y; Rebouissou S; Béraud C; Lang H; Massfelder T; Allory Y; Cianférani S; Stote RH; Radvanyi F; Bernard-Pierrot I
Nat Commun; 2019 Jan; 10(1):253. PubMed ID: 30651555
[TBL] [Abstract][Full Text] [Related]
18. Partial agonists activate PPARgamma using a helix 12 independent mechanism.
Bruning JB; Chalmers MJ; Prasad S; Busby SA; Kamenecka TM; He Y; Nettles KW; Griffin PR
Structure; 2007 Oct; 15(10):1258-71. PubMed ID: 17937915
[TBL] [Abstract][Full Text] [Related]
19. Ligand entry pathways in the ligand binding domain of PPARγ receptor.
Aci-Sèche S; Genest M; Garnier N
FEBS Lett; 2011 Aug; 585(16):2599-603. PubMed ID: 21782815
[TBL] [Abstract][Full Text] [Related]
20. Molecular binding sites are located near the interface of intrinsic dynamics domains (IDDs).
Li H; Sakuraba S; Chandrasekaran A; Yang LW
J Chem Inf Model; 2014 Aug; 54(8):2275-85. PubMed ID: 25089914
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]