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2. Identification of a 4-mer peptide inhibitor that effectively blocks the polymerization of pathogenic Z alpha1-antitrypsin. Chang YP; Mahadeva R; Chang WS; Shukla A; Dafforn TR; Chu YH Am J Respir Cell Mol Biol; 2006 Nov; 35(5):540-8. PubMed ID: 16778151 [TBL] [Abstract][Full Text] [Related]
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8. Preventing and reversing the cellular consequences of Z alpha-1 antitrypsin accumulation by targeting s4A. Alam S; Wang J; Janciauskiene S; Mahadeva R J Hepatol; 2012 Jul; 57(1):116-24. PubMed ID: 22425623 [TBL] [Abstract][Full Text] [Related]
9. Heteropolymerization of S, I, and Z alpha1-antitrypsin and liver cirrhosis. Mahadeva R; Chang WS; Dafforn TR; Oakley DJ; Foreman RC; Calvin J; Wight DG; Lomas DA J Clin Invest; 1999 Apr; 103(7):999-1006. PubMed ID: 10194472 [TBL] [Abstract][Full Text] [Related]
10. An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1 -antitrypsin upon ligand binding. Nyon MP; Prentice T; Day J; Kirkpatrick J; Sivalingam GN; Levy G; Haq I; Irving JA; Lomas DA; Christodoulou J; Gooptu B; Thalassinos K Protein Sci; 2015 Aug; 24(8):1301-12. PubMed ID: 26011795 [TBL] [Abstract][Full Text] [Related]
11. Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema. Elliott PR; Bilton D; Lomas DA Am J Respir Cell Mol Biol; 1998 May; 18(5):670-4. PubMed ID: 9569237 [TBL] [Abstract][Full Text] [Related]
12. The mechanism of alpha 1-antitrypsin polymerization probed by fluorescence spectroscopy. James EL; Bottomley SP Arch Biochem Biophys; 1998 Aug; 356(2):296-300. PubMed ID: 9705220 [TBL] [Abstract][Full Text] [Related]
13. Discovery of an inhibitor of Z-alpha1 antitrypsin polymerization. Berthelier V; Harris JB; Estenson KN; Baudry J PLoS One; 2015; 10(5):e0126256. PubMed ID: 25961288 [TBL] [Abstract][Full Text] [Related]
14. A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity. Ordóñez A; Pérez J; Tan L; Dickens JA; Motamedi-Shad N; Irving JA; Haq I; Ekeowa U; Marciniak SJ; Miranda E; Lomas DA FASEB J; 2015 Jun; 29(6):2667-78. PubMed ID: 25757566 [TBL] [Abstract][Full Text] [Related]
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18. The Z type variation of human alpha 1-antitrypsin causes a protein folding defect. Yu MH; Lee KN; Kim J Nat Struct Biol; 1995 May; 2(5):363-7. PubMed ID: 7664092 [TBL] [Abstract][Full Text] [Related]