124 related articles for article (PubMed ID: 1912294)
41. MPTP and MPTP analogs induced cell death in cultured rat hepatocytes involving the formation of pyridinium metabolites.
Singh Y; Swanson E; Sokoloski E; Kutty RK; Krishna G
Toxicol Appl Pharmacol; 1988 Nov; 96(2):347-59. PubMed ID: 3143167
[TBL] [Abstract][Full Text] [Related]
42. Potentiation by the tetraphenylboron anion of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its pyridinium metabolite.
Heikkila RE; Hwang J; Ofori S; Geller HM; Nicklas WJ
J Neurochem; 1990 Mar; 54(3):743-50. PubMed ID: 2303810
[TBL] [Abstract][Full Text] [Related]
43. Potential metabolic bioactivation pathways involving cyclic tertiary amines and azaarenes.
Castagnoli N; Rimoldi JM; Bloomquist J; Castagnoli KP
Chem Res Toxicol; 1997 Sep; 10(9):924-40. PubMed ID: 9305573
[TBL] [Abstract][Full Text] [Related]
44. Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Zhao Z; Mabic S; Kuttab S; Franot C; Castagnoli K; Castagnoli N
Bioorg Med Chem; 1998 Dec; 6(12):2531-9. PubMed ID: 9925309
[TBL] [Abstract][Full Text] [Related]
45. Haloperidol and its tetrahydropyridine derivative (HPTP) are metabolized to potentially neurotoxic pyridinium species in the baboon.
Avent KM; Usuki E; Eyles DW; Keeve R; Van der Schyf CJ; Castagnoli N; Pond SM
Life Sci; 1996; 59(17):1473-82. PubMed ID: 8890926
[TBL] [Abstract][Full Text] [Related]
46. Studies on 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Naiman N; Rollema H; Johnson E; Castagnoli N
Chem Res Toxicol; 1990; 3(2):133-8. PubMed ID: 2130940
[TBL] [Abstract][Full Text] [Related]
47. Species-dependent differences in monoamine oxidase A and B-catalyzed oxidation of various C4 substituted 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridinyl derivatives.
Inoue H; Castagnoli K; Van Der Schyf C; Mabic S; Igarashi K; Castagnoli N
J Pharmacol Exp Ther; 1999 Nov; 291(2):856-64. PubMed ID: 10525109
[TBL] [Abstract][Full Text] [Related]
48. Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline.
Ogunrombi MO; Malan SF; Terre'Blanche G; Castagnoli K; Castagnoli N; Bergh JJ; Petzer JP
Life Sci; 2007 Jul; 81(6):458-67. PubMed ID: 17655878
[TBL] [Abstract][Full Text] [Related]
49. Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products.
Youngster SK; McKeown KA; Jin YZ; Ramsay RR; Heikkila RE; Singer TP
J Neurochem; 1989 Dec; 53(6):1837-42. PubMed ID: 2809594
[TBL] [Abstract][Full Text] [Related]
50. Inhibition of rat brain monoamine oxidase by some analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion.
Arai Y; Kinemuchi H; Hamamichi N; Satoh N; Tadano T; Kisara K
Neurosci Lett; 1986 May; 66(1):43-8. PubMed ID: 3487053
[TBL] [Abstract][Full Text] [Related]
51. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
Pretorius A; Ogunrombi MO; Terre'blanche G; Castagnoli N; Bergh JJ; Petzer JP
Bioorg Med Chem; 2008 Oct; 16(19):8813-7. PubMed ID: 18799315
[TBL] [Abstract][Full Text] [Related]
52. Quantitative analysis of two pyridinium metabolites of haloperidol in patients with schizophrenia.
Eyles DW; McLennan HR; Jones A; McGrath JJ; Stedman TJ; Pond SM
Clin Pharmacol Ther; 1994 Nov; 56(5):512-20. PubMed ID: 7955815
[TBL] [Abstract][Full Text] [Related]
53. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Castagnoli N; Chiba K; Trevor AJ
Life Sci; 1985 Jan; 36(3):225-30. PubMed ID: 3871243
[TBL] [Abstract][Full Text] [Related]
54. Interactions of the 1-methyl-4-phenyl-2,3-dihydropyridinium species with synthetic dopamine-melanin.
Wu EY; Chiba K; Trevor AJ; Castagnoli N
Life Sci; 1986 Nov; 39(18):1695-700. PubMed ID: 3490611
[TBL] [Abstract][Full Text] [Related]
55. Importance of monoamine oxidase A in the bioactivation of neurotoxic analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Heikkila RE; Kindt MV; Sonsalla PK; Giovanni A; Youngster SK; McKeown KA; Singer TP
Proc Natl Acad Sci U S A; 1988 Aug; 85(16):6172-6. PubMed ID: 3137566
[TBL] [Abstract][Full Text] [Related]
56. Quantitative analysis of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism in isolated rat hepatocytes.
Di Monte D; Shinka T; Sandy MS; Castagnoli N; Smith MT
Drug Metab Dispos; 1988; 16(2):250-5. PubMed ID: 2898342
[TBL] [Abstract][Full Text] [Related]
57. N-methyltetrahydro-beta-carboline analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic beta-carbolinium cations by heme peroxidases.
Herraiz T; Guillén H; Galisteo J
Biochem Biophys Res Commun; 2007 Apr; 356(1):118-23. PubMed ID: 17346675
[TBL] [Abstract][Full Text] [Related]
58. Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine.
Kuttab S; Shang J; Castagnoli N
Bioorg Med Chem; 2001 Jul; 9(7):1685-9. PubMed ID: 11425568
[TBL] [Abstract][Full Text] [Related]
59. Contribution of N-oxygenation to the metabolism of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) by various liver preparations.
Cashman JR; Ziegler DM
Mol Pharmacol; 1986 Feb; 29(2):163-7. PubMed ID: 3485239
[TBL] [Abstract][Full Text] [Related]
60. Metabolic aromatization of N-alkyl-1,2,3,4-tetrahydroquinoline substructures to quinolinium by human liver microsomes and horseradish peroxidase.
Gu C; Collins R; Holsworth DD; Walker GS; Voorman RL
Drug Metab Dispos; 2006 Dec; 34(12):2044-55. PubMed ID: 16985099
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
