BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 19123984)

  • 1. Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice.
    Choi CY; Chan DA; Paulmurugan R; Sutphin PD; Le QT; Koong AC; Zundel W; Gambhir SS; Giaccia AJ
    Mol Imaging; 2008; 7(3):139-46. PubMed ID: 19123984
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
    Miller F; Kentsis A; Osman R; Pan ZQ
    J Biol Chem; 2005 Mar; 280(9):7985-96. PubMed ID: 15611064
    [TBL] [Abstract][Full Text] [Related]  

  • 3. von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay.
    Hong S; Yum S; Ha NC; Jung Y
    Anal Biochem; 2010 Dec; 407(2):220-5. PubMed ID: 20705044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
    J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
    Qian H; Zou Y; Tang Y; Gong Y; Qian Z; Wei G; Zhang Q
    Phys Chem Chem Phys; 2018 Jul; 20(27):18756-18765. PubMed ID: 29961792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
    André H; Pereira TS
    J Biol Chem; 2008 Oct; 283(43):29375-84. PubMed ID: 18694926
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization.
    Zheng X; Ruas JL; Cao R; Salomons FA; Cao Y; Poellinger L; Pereira T
    Mol Cell Biol; 2006 Jun; 26(12):4628-41. PubMed ID: 16738327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemical basis for the selectivity of the von Hippel Lindau tumor suppressor pVHL for prolyl-hydroxylated HIF-1alpha.
    Illingworth CJ; Loenarz C; Schofield CJ; Domene C
    Biochemistry; 2010 Aug; 49(32):6936-44. PubMed ID: 20695530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. VBP1 represses cancer metastasis by enhancing HIF-1α degradation induced by pVHL.
    Kim JA; Choi DK; Min JS; Kang I; Kim JC; Kim S; Ahn JK
    FEBS J; 2018 Jan; 285(1):115-126. PubMed ID: 29121446
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
    Cockman ME; Masson N; Mole DR; Jaakkola P; Chang GW; Clifford SC; Maher ER; Pugh CW; Ratcliffe PJ; Maxwell PH
    J Biol Chem; 2000 Aug; 275(33):25733-41. PubMed ID: 10823831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL).
    Heir P; Ohh M
    Methods Mol Biol; 2016; 1458():87-94. PubMed ID: 27581016
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha.
    Yuan Y; Hilliard G; Ferguson T; Millhorn DE
    J Biol Chem; 2003 May; 278(18):15911-6. PubMed ID: 12606543
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism.
    Tang TT; Lasky LA
    J Biol Chem; 2003 Aug; 278(32):30125-35. PubMed ID: 12761217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism of hypoxia-specific cytotoxicity of procaspase-3 fused with a VHL-mediated protein destruction motif of HIF-1alpha containing Pro564.
    Harada H; Kizaka-Kondoh S; Hiraoka M
    FEBS Lett; 2006 Oct; 580(24):5718-22. PubMed ID: 17010341
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of point mutations in pVHL on the binding of HIF-1α.
    Domene C; Illingworth CJ
    Proteins; 2012 Mar; 80(3):733-46. PubMed ID: 22105711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In silico investigation of PHD-3 specific HIF1-α proline 567 hydroxylation: a new player in the VHL/HIF-1α interaction pathway?
    Minervini G; Masiero A; Moro S; Tosatto SC
    FEBS Lett; 2013 Sep; 587(18):2996-3001. PubMed ID: 23886708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.
    Okumura F; Uematsu K; Byrne SD; Hirano M; Joo-Okumura A; Nishikimi A; Shuin T; Fukui Y; Nakatsukasa K; Kamura T
    Mol Cell Biol; 2016 Jun; 36(12):1803-17. PubMed ID: 27090638
    [TBL] [Abstract][Full Text] [Related]  

  • 18. STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.
    Jung JE; Kim HS; Lee CS; Shin YJ; Kim YN; Kang GH; Kim TY; Juhnn YS; Kim SJ; Park JW; Ye SK; Chung MH
    Exp Mol Med; 2008 Oct; 40(5):479-85. PubMed ID: 18985005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design.
    Liu J; Nussinov R
    Proc Natl Acad Sci U S A; 2008 Jan; 105(3):901-6. PubMed ID: 18195360
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Immunoexpression patterns for Hypoxia-inducible Factor-1α and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
    Assimakopoulou M; Androutsopoulou C; Zolota V; Matsoukas J
    Histol Histopathol; 2016 May; 31(5):535-46. PubMed ID: 26592496
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.