BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 19124250)

  • 1. Novel DNA-directed alkylating agents: design, synthesis and potent antitumor effect of phenyl N-mustard-9-anilinoacridine conjugates via a carbamate or carbonate linker.
    Kapuriya N; Kapuriya K; Dong H; Zhang X; Chou TC; Chen YT; Lee TC; Lee WC; Tsai TH; Naliapara Y; Su TL
    Bioorg Med Chem; 2009 Feb; 17(3):1264-75. PubMed ID: 19124250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity.
    Bacherikov VA; Chou TC; Dong HJ; Zhang X; Chen CH; Lin YW; Tsai TJ; Lee RZ; Liu LF; Su TL
    Bioorg Med Chem; 2005 Jun; 13(12):3993-4006. PubMed ID: 15911312
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes.
    Kakadiya R; Dong H; Lee PC; Kapuriya N; Zhang X; Chou TC; Lee TC; Kapuriya K; Shah A; Su TL
    Bioorg Med Chem; 2009 Aug; 17(15):5614-26. PubMed ID: 19576785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.
    Su TL; Lin YW; Chou TC; Zhang X; Bacherikov VA; Chen CH; Liu LF; Tsai TJ
    J Med Chem; 2006 Jun; 49(12):3710-8. PubMed ID: 16759114
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.
    Kapuriya N; Kapuriya K; Zhang X; Chou TC; Kakadiya R; Wu YT; Tsai TH; Chen YT; Lee TC; Shah A; Naliapara Y; Su TL
    Bioorg Med Chem; 2008 May; 16(10):5413-23. PubMed ID: 18450456
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent antitumor N-mustard derivatives of 9-anilinoacridine, synthesis and antitumor evaluation.
    Bacherikov VA; Chou TC; Dong HJ; Chen CH; Lin YW; Tsai TJ; Su TL
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4719-22. PubMed ID: 15324894
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and antitumor evaluation of phenyl N-mustard-quinazoline conjugates.
    Marvania B; Lee PC; Chaniyara R; Dong H; Suman S; Kakadiya R; Chou TC; Lee TC; Shah A; Su TL
    Bioorg Med Chem; 2011 Mar; 19(6):1987-98. PubMed ID: 21356592
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents.
    Kapuriya N; Kakadiya R; Dong H; Kumar A; Lee PC; Zhang X; Chou TC; Lee TC; Chen CH; Lam K; Marvania B; Shah A; Su TL
    Bioorg Med Chem; 2011 Jan; 19(1):471-85. PubMed ID: 21106377
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic cure against human tumor xenografts in nude mice by a microtubule stabilization agent, fludelone, via parenteral or oral route.
    Chou TC; Dong H; Zhang X; Tong WP; Danishefsky SJ
    Cancer Res; 2005 Oct; 65(20):9445-54. PubMed ID: 16230408
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent reversal of multidrug resistance by ningalins and its use in drug combinations against human colon carcinoma xenograft in nude mice.
    Chou TC; Guan Y; Soenen DR; Danishefsky SJ; Boger DL
    Cancer Chemother Pharmacol; 2005 Oct; 56(4):379-90. PubMed ID: 15875185
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker.
    Kakadiya R; Dong H; Kumar A; Narsinh D; Zhang X; Chou TC; Lee TC; Shah A; Su TL
    Bioorg Med Chem; 2010 Mar; 18(6):2285-2299. PubMed ID: 20181487
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.
    Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE
    Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.
    Varvaresou A; Iakovou K; Gikas E; Fichtner I; Fiebig HH; Kelland LR; Double JA; Bibby MC; Hendriks HR
    Anticancer Res; 2004; 24(2B):907-19. PubMed ID: 15161044
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel bifunctional alkylating agents, 5,10-dihydropyrrolo[1,2-b]isoquinoline derivatives, synthesis and biological activity.
    Chaniyara R; Kapuriya N; Dong H; Lee PC; Suman S; Marvania B; Chou TC; Lee TC; Kakadiya R; Shah A; Su TL
    Bioorg Med Chem; 2011 Jan; 19(1):275-86. PubMed ID: 21144756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP; Anderson RF; Ferry DM; Wilson WR; Denny WA
    J Med Chem; 2003 Dec; 46(25):5533-45. PubMed ID: 14640560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives.
    Bacherikov VA; Chang JY; Lin YW; Chen CH; Pan WY; Dong H; Lee RZ; Chou TC; Su TL
    Bioorg Med Chem; 2005 Dec; 13(23):6513-20. PubMed ID: 16140018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
    Atwell GJ; Fan JY; Tan K; Denny WA
    J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel.
    Yamori T; Matsunaga A; Sato S; Yamazaki K; Komi A; Ishizu K; Mita I; Edatsugi H; Matsuba Y; Takezawa K; Nakanishi O; Kohno H; Nakajima Y; Komatsu H; Andoh T; Tsuruo T
    Cancer Res; 1999 Aug; 59(16):4042-9. PubMed ID: 10463605
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 2: efficacy evaluations.
    Alley MC; Hollingshead MG; Pacula-Cox CM; Waud WR; Hartley JA; Howard PW; Gregson SJ; Thurston DE; Sausville EA
    Cancer Res; 2004 Sep; 64(18):6700-6. PubMed ID: 15374987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The synthesis and biological evaluation of new DNA-directed alkylating agents, phenyl N-mustard-4-anilinoquinoline conjugates containing a urea linker.
    Marvania B; Kakadiya R; Christian W; Chen TL; Wu MH; Suman S; Tala K; Lee TC; Shah A; Su TL
    Eur J Med Chem; 2014 Aug; 83():695-708. PubMed ID: 25014640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.