223 related articles for article (PubMed ID: 19124772)
1. O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.
Klapacz J; Meira LB; Luchetti DG; Calvo JA; Bronson RT; Edelmann W; Samson LD
Proc Natl Acad Sci U S A; 2009 Jan; 106(2):576-81. PubMed ID: 19124772
[TBL] [Abstract][Full Text] [Related]
2. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.
Kaina B; Ziouta A; Ochs K; Coquerelle T
Mutat Res; 1997 Nov; 381(2):227-41. PubMed ID: 9434879
[TBL] [Abstract][Full Text] [Related]
3. Repair of O(6)-methylguanine is not affected by thymine base pairing and the presence of MMR proteins.
Lips J; Kaina B
Mutat Res; 2001 Nov; 487(1-2):59-66. PubMed ID: 11595409
[TBL] [Abstract][Full Text] [Related]
4. Mutational-reporter transgenes rescued from mice lacking either Mgmt, or both Mgmt and Msh6 suggest that O6-alkylguanine-induced miscoding does not contribute to the spontaneous mutational spectrum.
Sandercock LE; Kwok MC; Luchman HA; Mark SC; Giesbrecht JL; Samson LD; Jirik FR
Oncogene; 2004 Aug; 23(35):5931-40. PubMed ID: 15208683
[TBL] [Abstract][Full Text] [Related]
5. Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis.
Nyskohus LS; Watson AJ; Margison GP; Le Leu RK; Kim SW; Lockett TJ; Head RJ; Young GP; Hu Y
Mutat Res Genet Toxicol Environ Mutagen; 2013 Dec; 758(1-2):80-6. PubMed ID: 24140386
[TBL] [Abstract][Full Text] [Related]
6. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
Kaina B; Christmann M; Naumann S; Roos WP
DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
[TBL] [Abstract][Full Text] [Related]
7. BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis.
Kaina B; Ochs K; Grösch S; Fritz G; Lips J; Tomicic M; Dunkern T; Christmann M
Prog Nucleic Acid Res Mol Biol; 2001; 68():41-54. PubMed ID: 11554312
[TBL] [Abstract][Full Text] [Related]
8. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Roos W; Baumgartner M; Kaina B
Oncogene; 2004 Jan; 23(2):359-67. PubMed ID: 14724564
[TBL] [Abstract][Full Text] [Related]
9. Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.
Roos WP; Nikolova T; Quiros S; Naumann SC; Kiedron O; Zdzienicka MZ; Kaina B
DNA Repair (Amst); 2009 Jan; 8(1):72-86. PubMed ID: 18840549
[TBL] [Abstract][Full Text] [Related]
10. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents.
Christmann M; Kaina B
J Biol Chem; 2000 Nov; 275(46):36256-62. PubMed ID: 10954713
[TBL] [Abstract][Full Text] [Related]
11. Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair.
Roos WP; Christmann M; Fraser ST; Kaina B
Cell Death Differ; 2007 Aug; 14(8):1422-32. PubMed ID: 17464330
[TBL] [Abstract][Full Text] [Related]
12. ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.
Yoshioka K; Yoshioka Y; Hsieh P
Mol Cell; 2006 May; 22(4):501-10. PubMed ID: 16713580
[TBL] [Abstract][Full Text] [Related]
13. Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis.
Takagi Y; Takahashi M; Sanada M; Ito R; Yamaizumi M; Sekiguchi M
DNA Repair (Amst); 2003 Oct; 2(10):1135-46. PubMed ID: 13679151
[TBL] [Abstract][Full Text] [Related]
14. Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins.
Bugni JM; Meira LB; Samson LD
Oncogene; 2009 Feb; 28(5):734-41. PubMed ID: 19029948
[TBL] [Abstract][Full Text] [Related]
15. Exo1 independent DNA mismatch repair involves multiple compensatory nucleases.
Desai A; Gerson S
DNA Repair (Amst); 2014 Sep; 21():55-64. PubMed ID: 25037770
[TBL] [Abstract][Full Text] [Related]
16. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
[TBL] [Abstract][Full Text] [Related]
17. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.
Wirtz S; Nagel G; Eshkind L; Neurath MF; Samson LD; Kaina B
Carcinogenesis; 2010 Dec; 31(12):2111-7. PubMed ID: 20732909
[TBL] [Abstract][Full Text] [Related]
18. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O
Kraus A; McKeague M; Seiwert N; Nagel G; Geisen SM; Ziegler N; Trantakis IA; Kaina B; Thomas AD; Sturla SJ; Fahrer J
Arch Toxicol; 2019 Feb; 93(2):559-572. PubMed ID: 30446773
[TBL] [Abstract][Full Text] [Related]
19. O6-methylguanine and O6-methylguanine-DNA [corrected] methyltransferase activity in tissues of BDF-1 mice treated with antiparasitic drugs.
Badawi AF
Toxicol Lett; 1998 Feb; 94(3):199-208. PubMed ID: 9609323
[TBL] [Abstract][Full Text] [Related]
20. Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles.
Quiros S; Roos WP; Kaina B
Cell Cycle; 2010 Jan; 9(1):168-78. PubMed ID: 20016283
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
