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2. Deprenyl antagonizes acute lethality of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Fuller RW; Hemrick-Luecke SK; Perry KW J Pharmacol Exp Ther; 1988 Nov; 247(2):531-5. PubMed ID: 3141609 [TBL] [Abstract][Full Text] [Related]
3. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuroblastic apoptosis in the subventricular zone is caused by 1-methy-4-phenylpiridinium (MPP(+)) converted from MPTP through MAO-B. Ito T; Suzuki K; Uchida K; Nakayama H Exp Toxicol Pathol; 2012 Nov; 64(7-8):761-5. PubMed ID: 21324658 [TBL] [Abstract][Full Text] [Related]
4. Monoamine oxidase B(MAO-B) is the major catalyst for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) oxidation in human brain and other tissues. Glover V; Gibb C; Sandler M Neurosci Lett; 1986 Feb; 64(2):216-20. PubMed ID: 3083305 [TBL] [Abstract][Full Text] [Related]
5. Toxicity of MPTP and structural analogs in clonal cell lines of neuronal origin expressing B type monoamine oxidase activity. Buckman TD Mol Chem Neuropathol; 1991 Oct; 15(2):87-102. PubMed ID: 1776993 [TBL] [Abstract][Full Text] [Related]
7. Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline. Kupsch A; Sautter J; Götz ME; Breithaupt W; Schwarz J; Youdim MB; Riederer P; Gerlach M; Oertel WH J Neural Transm (Vienna); 2001; 108(8-9):985-1009. PubMed ID: 11716151 [TBL] [Abstract][Full Text] [Related]
8. Characterization of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) binding sites in C57BL/6 mouse brain: mutual effects of monoamine oxidase inhibitors and sigma ligands on MPTP and sigma binding sites. Itzhak Y; Mash D; Zhang SH; Stein I Mol Pharmacol; 1991 Mar; 39(3):385-93. PubMed ID: 1848660 [TBL] [Abstract][Full Text] [Related]
9. Different effects of monoamine oxidase inhibition on MPTP depletion of heart and brain catecholamines in mice. Fuller RW; Hemrick-Luecke SK; Kindt MV; Heikkila RE Life Sci; 1988; 42(3):263-71. PubMed ID: 3121972 [TBL] [Abstract][Full Text] [Related]
10. Age-dependent effects of the 2'-methyl analog of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine: prevention by inhibitors of monoamine oxidase B. Finnegan KT; Irwin I; Delanney LE; Langston JW J Pharmacol Exp Ther; 1995 May; 273(2):716-20. PubMed ID: 7752075 [TBL] [Abstract][Full Text] [Related]
11. Involvement of monoamine oxidase enzymes in the action of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, a selective neurotoxin, in the squirrel monkey: binding and biochemical studies. Del Zompo M; Piccardi MP; Bernardi F; Bonuccelli U; Corsini GU Brain Res; 1986 Jul; 378(2):320-4. PubMed ID: 3089539 [TBL] [Abstract][Full Text] [Related]
12. Comparison of the effects of two 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs, 1-methyl-4-(2-thienyl)-1,2,3,6-tetrahydropyridine and 1-methyl-4-(3-thienyl)-1,2,3,6-tetrahydropyridine, on monoamine oxidase in vitro and on dopamine in mouse brain. Fuller RW; Robertson DW; Hemrick-Luecke SK J Pharmacol Exp Ther; 1987 Feb; 240(2):415-20. PubMed ID: 3100775 [TBL] [Abstract][Full Text] [Related]
13. The role of MAO in MPTP toxicity--a review. Glover V; Gibb C; Sandler M J Neural Transm Suppl; 1986; 20():65-76. PubMed ID: 3091762 [TBL] [Abstract][Full Text] [Related]
14. Neuroprotection by (R)-deprenyl and 7-nitroindazole in the MPTP C57BL/6 mouse model of neurotoxicity. Castagnoli K; Palmer S; Castagnoli N Neurobiology (Bp); 1999; 7(2):135-49. PubMed ID: 10591048 [TBL] [Abstract][Full Text] [Related]
15. Depletion of norepinephrine in mouse heart by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mimicked by 1-methyl-4-phenylpyridinium (MPP+) and not blocked by deprenyl. Fuller RW; Hemrick-Luecke SK Life Sci; 1986 Nov; 39(18):1645-50. PubMed ID: 3095601 [TBL] [Abstract][Full Text] [Related]
16. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A. Basma AN; Heikkila RE; Nicklas WJ; Giovanni A; Geller HM J Neurochem; 1990 Sep; 55(3):870-7. PubMed ID: 2384758 [TBL] [Abstract][Full Text] [Related]
17. Importance of monoamine oxidase A in the bioactivation of neurotoxic analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Heikkila RE; Kindt MV; Sonsalla PK; Giovanni A; Youngster SK; McKeown KA; Singer TP Proc Natl Acad Sci U S A; 1988 Aug; 85(16):6172-6. PubMed ID: 3137566 [TBL] [Abstract][Full Text] [Related]
18. Selegiline can mediate neuronal rescue rather than neuronal protection. Tatton WG Mov Disord; 1993; 8 Suppl 1():S20-30. PubMed ID: 8302304 [TBL] [Abstract][Full Text] [Related]
19. Prevention of MPTP-induced neurotoxicity by AGN-1133 and AGN-1135, selective inhibitors of monoamine oxidase-B. Heikkila RE; Duvoisin RC; Finberg JP; Youdim MB Eur J Pharmacol; 1985 Oct; 116(3):313-7. PubMed ID: 3935467 [TBL] [Abstract][Full Text] [Related]
20. Evaluation of the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to toxic pyridinium cations by monoamine oxidase (MAO) enzymes and its use to search for new MAO inhibitors and protective agents. Herraiz T J Enzyme Inhib Med Chem; 2012 Dec; 27(6):810-7. PubMed ID: 21992679 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]