These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Detection of glutathione conjugates derived from 4-ipomeanol metabolism in bile of rats by liquid chromatography-tandem mass spectrometry. Alvarez-Diez TM; Zheng J Drug Metab Dispos; 2004 Dec; 32(12):1345-50. PubMed ID: 15328249 [TBL] [Abstract][Full Text] [Related]
7. Conjugated dienes as prohaptens in contact allergy: in vivo and in vitro studies of structure-activity relationships, sensitizing capacity, and metabolic activation. Bergström MA; Luthman K; Nilsson JL; Karlberg AT Chem Res Toxicol; 2006 Jun; 19(6):760-9. PubMed ID: 16780354 [TBL] [Abstract][Full Text] [Related]
8. A conjugated diene identified as a prohapten: contact allergenic activity and chemical reactivity of proposed epoxide metabolites. Nilsson AM; Bergström MA; Luthman K; Nilsson JL; Karlberg AT Chem Res Toxicol; 2005 Feb; 18(2):308-16. PubMed ID: 15720137 [TBL] [Abstract][Full Text] [Related]
9. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s. Wen B; Ma L; Zhu M Chem Biol Interact; 2008 May; 173(1):59-67. PubMed ID: 18359012 [TBL] [Abstract][Full Text] [Related]
10. Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites. Avent KM; DeVoss JJ; Gillam EM Chem Res Toxicol; 2006 Jul; 19(7):914-20. PubMed ID: 16841959 [TBL] [Abstract][Full Text] [Related]
11. Comparisons of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: effect of redox state and expression levels. Quinn AM; Penning TM Chem Res Toxicol; 2008 May; 21(5):1086-94. PubMed ID: 18402469 [TBL] [Abstract][Full Text] [Related]
12. Bioactivation of 4-methylphenol (p-cresol) via cytochrome P450-mediated aromatic oxidation in human liver microsomes. Yan Z; Zhong HM; Maher N; Torres R; Leo GC; Caldwell GW; Huebert N Drug Metab Dispos; 2005 Dec; 33(12):1867-76. PubMed ID: 16174805 [TBL] [Abstract][Full Text] [Related]
13. 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid. Deo AK; Bandiera SM Drug Metab Dispos; 2009 Sep; 37(9):1938-47. PubMed ID: 19487251 [TBL] [Abstract][Full Text] [Related]
14. Bioactivation of flutamide metabolites by human liver microsomes. Kang P; Dalvie D; Smith E; Zhou S; Deese A; Nieman JA Drug Metab Dispos; 2008 Jul; 36(7):1425-37. PubMed ID: 18411402 [TBL] [Abstract][Full Text] [Related]
15. An alpha,beta-unsaturated oxime identified as a strong contact allergen. Indications of antigen formation via several pathways. Nilsson AM; Bergström MA; Luthman K; Nilsson JL; Karlberg AT Food Chem Toxicol; 2005 Nov; 43(11):1627-36. PubMed ID: 15978713 [TBL] [Abstract][Full Text] [Related]
16. Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives. Fujioka K; Casida JE Chem Res Toxicol; 2007 Aug; 20(8):1211-7. PubMed ID: 17645302 [TBL] [Abstract][Full Text] [Related]
17. Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening. Van Liempd SM; Kool J; Meerman JH; Irth H; Vermeulen NP Chem Res Toxicol; 2007 Dec; 20(12):1825-32. PubMed ID: 17975887 [TBL] [Abstract][Full Text] [Related]
18. Metabolism and bioactivation of 3-methylindole by human liver microsomes. Yan Z; Easterwood LM; Maher N; Torres R; Huebert N; Yost GS Chem Res Toxicol; 2007 Jan; 20(1):140-8. PubMed ID: 17226936 [TBL] [Abstract][Full Text] [Related]
19. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine. Zhao SX; Dalvie DK; Kelly JM; Soglia JR; Frederick KS; Smith EB; Obach RS; Kalgutkar AS Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785 [TBL] [Abstract][Full Text] [Related]
20. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation. Grillo MP; Ma J; Teffera Y; Waldon DJ Drug Metab Dispos; 2008 Sep; 36(9):1740-4. PubMed ID: 18541695 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]