308 related articles for article (PubMed ID: 19127022)
1. Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice.
Takimoto E; Koitabashi N; Hsu S; Ketner EA; Zhang M; Nagayama T; Bedja D; Gabrielson KL; Blanton R; Siderovski DP; Mendelsohn ME; Kass DA
J Clin Invest; 2009 Feb; 119(2):408-20. PubMed ID: 19127022
[TBL] [Abstract][Full Text] [Related]
2. Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition.
Nishida M; Watanabe K; Sato Y; Nakaya M; Kitajima N; Ide T; Inoue R; Kurose H
J Biol Chem; 2010 Apr; 285(17):13244-53. PubMed ID: 20177073
[TBL] [Abstract][Full Text] [Related]
3. Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway.
Hsu S; Nagayama T; Koitabashi N; Zhang M; Zhou L; Bedja D; Gabrielson KL; Molkentin JD; Kass DA; Takimoto E
Cardiovasc Res; 2009 Feb; 81(2):301-9. PubMed ID: 19029137
[TBL] [Abstract][Full Text] [Related]
4. Chronic inhibition of cGMP-specific phosphodiesterase 5 suppresses endoplasmic reticulum stress in heart failure.
Gong W; Duan Q; Cai Z; Chen C; Ni L; Yan M; Wang X; Cianflone K; Wang DW
Br J Pharmacol; 2013 Dec; 170(7):1396-409. PubMed ID: 24032459
[TBL] [Abstract][Full Text] [Related]
5. PDE5 inhibitor efficacy is estrogen dependent in female heart disease.
Sasaki H; Nagayama T; Blanton RM; Seo K; Zhang M; Zhu G; Lee DI; Bedja D; Hsu S; Tsukamoto O; Takashima S; Kitakaze M; Mendelsohn ME; Karas RH; Kass DA; Takimoto E
J Clin Invest; 2014 Jun; 124(6):2464-71. PubMed ID: 24837433
[TBL] [Abstract][Full Text] [Related]
6. Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.
Patrucco E; Domes K; Sbroggió M; Blaich A; Schlossmann J; Desch M; Rybalkin SD; Beavo JA; Lukowski R; Hofmann F
Proc Natl Acad Sci U S A; 2014 Sep; 111(35):12925-9. PubMed ID: 25139994
[TBL] [Abstract][Full Text] [Related]
7. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition.
Koitabashi N; Aiba T; Hesketh GG; Rowell J; Zhang M; Takimoto E; Tomaselli GF; Kass DA
J Mol Cell Cardiol; 2010 Apr; 48(4):713-24. PubMed ID: 19961855
[TBL] [Abstract][Full Text] [Related]
8. Oxidative stress regulates left ventricular PDE5 expression in the failing heart.
Lu Z; Xu X; Hu X; Lee S; Traverse JH; Zhu G; Fassett J; Tao Y; Zhang P; dos Remedios C; Pritzker M; Hall JL; Garry DJ; Chen Y
Circulation; 2010 Apr; 121(13):1474-83. PubMed ID: 20308615
[TBL] [Abstract][Full Text] [Related]
9. PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.
Lee DI; Vahebi S; Tocchetti CG; Barouch LA; Solaro RJ; Takimoto E; Kass DA
Basic Res Cardiol; 2010 May; 105(3):337-47. PubMed ID: 20107996
[TBL] [Abstract][Full Text] [Related]
10. Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation.
Nakamura T; Zhu G; Ranek MJ; Kokkonen-Simon K; Zhang M; Kim GE; Tsujita K; Kass DA
Circ Heart Fail; 2018 Mar; 11(3):e004740. PubMed ID: 29545395
[TBL] [Abstract][Full Text] [Related]
11. cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium.
Vandeput F; Krall J; Ockaili R; Salloum FN; Florio V; Corbin JD; Francis SH; Kukreja RC; Movsesian MA
J Pharmacol Exp Ther; 2009 Sep; 330(3):884-91. PubMed ID: 19546307
[TBL] [Abstract][Full Text] [Related]
12. Gq/11-mediated signaling and hypertrophy in mice with cardiac-specific transgenic expression of regulator of G-protein signaling 2.
Park-Windhol C; Zhang P; Zhu M; Su J; Chaves L; Maldonado AE; King ME; Rickey L; Cullen D; Mende U
PLoS One; 2012; 7(7):e40048. PubMed ID: 22802950
[TBL] [Abstract][Full Text] [Related]
13. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.
Takimoto E; Champion HC; Li M; Belardi D; Ren S; Rodriguez ER; Bedja D; Gabrielson KL; Wang Y; Kass DA
Nat Med; 2005 Feb; 11(2):214-22. PubMed ID: 15665834
[TBL] [Abstract][Full Text] [Related]
14. Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil.
Nagayama T; Zhang M; Hsu S; Takimoto E; Kass DA
J Pharmacol Exp Ther; 2008 Aug; 326(2):380-7. PubMed ID: 18456872
[TBL] [Abstract][Full Text] [Related]
15. Endothelin receptor blockade combined with phosphodiesterase-5 inhibition increases right ventricular mitochondrial capacity in pulmonary arterial hypertension.
Mouchaers KT; Schalij I; Versteilen AM; Hadi AM; van Nieuw Amerongen GP; van Hinsbergh VW; Postmus PE; van der Laarse WJ; Vonk-Noordegraaf A
Am J Physiol Heart Circ Physiol; 2009 Jul; 297(1):H200-7. PubMed ID: 19395550
[TBL] [Abstract][Full Text] [Related]
16. Protein kinase g iα inhibits pressure overload-induced cardiac remodeling and is required for the cardioprotective effect of sildenafil in vivo.
Blanton RM; Takimoto E; Lane AM; Aronovitz M; Piotrowski R; Karas RH; Kass DA; Mendelsohn ME
J Am Heart Assoc; 2012 Oct; 1(5):e003731. PubMed ID: 23316302
[TBL] [Abstract][Full Text] [Related]
17. Pressure-overload magnitude-dependence of the anti-hypertrophic efficacy of PDE5A inhibition.
Nagayama T; Hsu S; Zhang M; Koitabashi N; Bedja D; Gabrielson KL; Takimoto E; Kass DA
J Mol Cell Cardiol; 2009 Apr; 46(4):560-7. PubMed ID: 19159628
[TBL] [Abstract][Full Text] [Related]
18. Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
Takimoto E; Belardi D; Tocchetti CG; Vahebi S; Cormaci G; Ketner EA; Moens AL; Champion HC; Kass DA
Circulation; 2007 Apr; 115(16):2159-67. PubMed ID: 17420342
[TBL] [Abstract][Full Text] [Related]
19. Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells.
Farrow KN; Lee KJ; Perez M; Schriewer JM; Wedgwood S; Lakshminrusimha S; Smith CL; Steinhorn RH; Schumacker PT
Antioxid Redox Signal; 2012 Aug; 17(3):460-70. PubMed ID: 22229392
[TBL] [Abstract][Full Text] [Related]
20. Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy.
Zhang W; Anger T; Su J; Hao J; Xu X; Zhu M; Gach A; Cui L; Liao R; Mende U
J Biol Chem; 2006 Mar; 281(9):5811-20. PubMed ID: 16380388
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
