BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

728 related articles for article (PubMed ID: 19130884)

  • 21. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
    Mangiarini L; Sathasivam K; Seller M; Cozens B; Harper A; Hetherington C; Lawton M; Trottier Y; Lehrach H; Davies SW; Bates GP
    Cell; 1996 Nov; 87(3):493-506. PubMed ID: 8898202
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Increased calbindin-D28k immunoreactivity in striatal projection neurons of R6/2 Huntington's disease transgenic mice.
    Sun Z; Wang HB; Deng YP; Lei WL; Xie JP; Meade CA; Del Mar N; Goldowitz D; Reiner A
    Neurobiol Dis; 2005 Dec; 20(3):907-17. PubMed ID: 15990326
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Transgenic models of Huntington's disease.
    Sathasivam K; Hobbs C; Mangiarini L; Mahal A; Turmaine M; Doherty P; Davies SW; Bates GP
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):963-9. PubMed ID: 10434294
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Transcription elongation and tissue-specific somatic CAG instability.
    Goula AV; Stys A; Chan JP; Trottier Y; Festenstein R; Merienne K
    PLoS Genet; 2012; 8(11):e1003051. PubMed ID: 23209427
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease.
    Moffitt H; McPhail GD; Woodman B; Hobbs C; Bates GP
    PLoS One; 2009 Nov; 4(11):e8025. PubMed ID: 19956633
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients.
    Sathasivam K; Woodman B; Mahal A; Bertaux F; Wanker EE; Shima DT; Bates GP
    Hum Mol Genet; 2001 Oct; 10(21):2425-35. PubMed ID: 11689489
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.
    Cheng HM; Chern Y; Chen IH; Liu CR; Li SH; Chun SJ; Rigo F; Bennett CF; Deng N; Feng Y; Lin CS; Yan YT; Cohen SN; Cheng TH
    PLoS Genet; 2015 Mar; 11(3):e1005043. PubMed ID: 25760041
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice.
    Spires TL; Grote HE; Garry S; Cordery PM; Van Dellen A; Blakemore C; Hannan AJ
    Eur J Neurosci; 2004 May; 19(10):2799-807. PubMed ID: 15147313
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Autopsy-proven Huntington's disease with 29 trinucleotide repeats.
    Kenney C; Powell S; Jankovic J
    Mov Disord; 2007 Jan; 22(1):127-30. PubMed ID: 17115386
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Huntingtin inclusions do not down-regulate specific genes in the R6/2 Huntington's disease mouse.
    Sadri-Vakili G; Menon AS; Farrell LA; Keller-McGandy CE; Cantuti-Castelvetri I; Standaert DG; Augood SJ; Yohrling GJ; Cha JH
    Eur J Neurosci; 2006 Jun; 23(12):3171-5. PubMed ID: 16820007
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene.
    Hansson O; Guatteo E; Mercuri NB; Bernardi G; Li XJ; Castilho RF; Brundin P
    Eur J Neurosci; 2001 Nov; 14(9):1492-504. PubMed ID: 11722611
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
    Ishiguro H; Yamada K; Sawada H; Nishii K; Ichino N; Sawada M; Kurosawa Y; Matsushita N; Kobayashi K; Goto J; Hashida H; Masuda N; Kanazawa I; Nagatsu T
    J Neurosci Res; 2001 Aug; 65(4):289-97. PubMed ID: 11494364
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice.
    Larson E; Fyfe I; Morton AJ; Monckton DG
    Neurobiol Dis; 2015 Apr; 76():98-111. PubMed ID: 25662336
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.
    Seo H; Kim W; Isacson O
    Hum Mol Genet; 2008 Oct; 17(20):3144-53. PubMed ID: 18640989
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease.
    Tang B; Seredenina T; Coppola G; Kuhn A; Geschwind DH; Luthi-Carter R; Thomas EA
    Neurobiol Dis; 2011 Jun; 42(3):459-67. PubMed ID: 21334439
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
    Gu X; Richman J; Langfelder P; Wang N; Zhang S; Bañez-Coronel M; Wang HB; Yang L; Ramanathan L; Deng L; Park CS; Choi CR; Cantle JP; Gao F; Gray M; Coppola G; Bates GP; Ranum LPW; Horvath S; Colwell CS; Yang XW
    Neuron; 2022 Apr; 110(7):1173-1192.e7. PubMed ID: 35114102
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
    Aldous SG; Smith EJ; Landles C; Osborne GF; Cañibano-Pico M; Nita IM; Phillips J; Zhang Y; Jin B; Hirst MB; Benn CL; Bond BC; Edelmann W; Greene JR; Bates GP
    Brain; 2024 May; 147(5):1784-1798. PubMed ID: 38387080
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease.
    Milnerwood AJ; Cummings DM; Dallérac GM; Brown JY; Vatsavayai SC; Hirst MC; Rezaie P; Murphy KP
    Hum Mol Genet; 2006 May; 15(10):1690-703. PubMed ID: 16600988
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease.
    Turmaine M; Raza A; Mahal A; Mangiarini L; Bates GP; Davies SW
    Proc Natl Acad Sci U S A; 2000 Jul; 97(14):8093-7. PubMed ID: 10869421
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice.
    Young D; Mayer F; Vidotto N; Schweizer T; Berth R; Abramowski D; Shimshek DR; van der Putten PH; Schmid P
    PLoS One; 2013; 8(9):e75108. PubMed ID: 24086450
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 37.