117 related articles for article (PubMed ID: 19136259)
1. Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA; Abdellatif KR; Dong Y; Rahman M; Das D; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2009 Feb; 19(3):584-8. PubMed ID: 19136259
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: a novel class of 5-lipoxygenase inhibitors.
Chowdhury MA; Chen H; Abdellatif KR; Dong Y; Petruk KC; Knaus EE
Bioorg Med Chem Lett; 2008 Jul; 18(14):4195-8. PubMed ID: 18541424
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
J Med Chem; 2009 Mar; 52(6):1525-9. PubMed ID: 19296694
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Dec; 13(23):6425-34. PubMed ID: 16099663
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.
Yu G; Praveen Rao PN; Chowdhury MA; Abdellatif KR; Dong Y; Das D; Velázquez CA; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2010 Apr; 20(7):2168-73. PubMed ID: 20202839
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA; Abdellatif KR; Dong Y; Das D; Yu G; Velázquez CA; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2009 Dec; 19(24):6855-61. PubMed ID: 19884005
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers.
Chowdhury MA; Dong Y; Chen QH; Abdellatif KR; Knaus EE
Bioorg Med Chem; 2008 Feb; 16(4):1948-56. PubMed ID: 18023187
[TBL] [Abstract][Full Text] [Related]
9. Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Yu G; Chowdhury MA; Abdellatif KR; Dong Y; Praveen Rao PN; Das D; Velázquez CA; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2010 Feb; 20(3):896-902. PubMed ID: 20045320
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
Moreau A; Chen QH; Praveen Rao PN; Knaus EE
Bioorg Med Chem; 2006 Dec; 14(23):7716-27. PubMed ID: 16931030
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.
Chowdhury MA; Huang Z; Abdellatif KR; Dong Y; Yu G; Velázquez CA; Knaus EE
Bioorg Med Chem Lett; 2010 Oct; 20(19):5776-80. PubMed ID: 20727750
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of acyclic triaryl (Z)-olefins possessing a 3,5-di-tert-butyl-4-hydroxyphenyl pharmacophore: dual inhibitors of cyclooxygenases and lipoxygenases.
Moreau A; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Aug; 14(15):5340-50. PubMed ID: 16677817
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Apr; 13(7):2459-68. PubMed ID: 15755648
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors.
Anana R; Rao PN; Chen QH; Knaus EE
Bioorg Med Chem; 2006 Aug; 14(15):5259-65. PubMed ID: 16635574
[TBL] [Abstract][Full Text] [Related]
18. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
Abdellatif KR; Chowdhury MA; Dong Y; Velázquez C; Das D; Suresh MR; Knaus EE
Bioorg Med Chem; 2008 Nov; 16(22):9694-8. PubMed ID: 18930406
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors.
Rao PN; Uddin MJ; Knaus EE
J Med Chem; 2004 Jul; 47(16):3972-90. PubMed ID: 15267236
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors.
Zarghi A; Zebardast T; Hakimion F; Shirazi FH; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Oct; 14(20):7044-50. PubMed ID: 16798002
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
