BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

498 related articles for article (PubMed ID: 1913675)

  • 1. O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Peterson LA; Hecht SS
    Cancer Res; 1991 Oct; 51(20):5557-64. PubMed ID: 1913675
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
    Peterson LA; Thomson NM; Crankshaw DL; Donaldson EE; Kenney PJ
    Cancer Res; 2001 Aug; 61(15):5757-63. PubMed ID: 11479212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.
    Ronai ZA; Gradia S; Peterson LA; Hecht SS
    Carcinogenesis; 1993 Nov; 14(11):2419-22. PubMed ID: 7902220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyridyloxobutyl DNA adducts inhibit the repair of O6-methylguanine.
    Peterson LA; Liu XK; Hecht SS
    Cancer Res; 1993 Jun; 53(12):2780-5. PubMed ID: 8504419
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM; Kenney PM; Peterson LA
    Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Morse MA; LaGreca SD; Amin SG; Chung FL
    Cancer Res; 1990 May; 50(9):2613-7. PubMed ID: 2328487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR; McIntee EJ; Kenney PM; Upadhyaya P; Peterson LA; Hecht SS
    Chem Res Toxicol; 2003 Jun; 16(6):794-806. PubMed ID: 12807363
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice.
    Hecht SS; Jordan KG; Choi CI; Trushin N
    Carcinogenesis; 1990 Jun; 11(6):1017-20. PubMed ID: 2347060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
    Morse MA; Wang CX; Amin SG; Hecht SS; Chung FL
    Carcinogenesis; 1988 Oct; 9(10):1891-5. PubMed ID: 3168166
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Immunocytochemical identification of DNA adducts, O6-methylguanine and 7-methylguanine, in respiratory and other tissues of rat, mouse and Syrian hamster exposed to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Van Benthem J; Feron VJ; Leeman WR; Wilmer JW; Vermeulen E; den Engelse L; Scherer E
    Carcinogenesis; 1994 Sep; 15(9):2023-9. PubMed ID: 7522985
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumorigenic activity of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanol (iso-NNAL) and N'-nitrosonornicotine (NNN) on topical application to Sencar mice.
    LaVoie EJ; Prokopczyk G; Rigotty J; Czech A; Rivenson A; Adams JD
    Cancer Lett; 1987 Nov; 37(3):277-83. PubMed ID: 3677059
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
    Hecht SS; Trushin N; Castonguay A; Rivenson A
    Cancer Res; 1986 Feb; 46(2):498-502. PubMed ID: 3940627
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
    Brown BG; Richter E; Tricker AR; Ayres PH; Doolittle DJ
    Chem Biol Interact; 2001 Nov; 138(2):125-35. PubMed ID: 11672696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tobacco-specific nitrosamine adducts: studies in laboratory animals and humans.
    Hecht SS; Carmella SG; Foiles PG; Murphy SE; Peterson LA
    Environ Health Perspect; 1993 Mar; 99():57-63. PubMed ID: 8319660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured F344 rat oral tissue and esophagus.
    Murphy SE; Heiblum R; Trushin N
    Cancer Res; 1990 Aug; 50(15):4685-91. PubMed ID: 2369743
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Accumulation and persistence of DNA adducts in respiratory tissue of rats following multiple administrations of the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
    Belinsky SA; White CM; Boucheron JA; Richardson FC; Swenberg JA; Anderson M
    Cancer Res; 1986 Mar; 46(3):1280-4. PubMed ID: 3943097
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E; Engl J; Friesenegger S; Tricker AR
    Chem Res Toxicol; 2009 Jun; 22(6):1008-17. PubMed ID: 19408892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence supporting the role of DNA pyridyloxobutylation in rat nasal carcinogenesis by tobacco-specific nitrosamines.
    Trushin N; Rivenson A; Hecht SS
    Cancer Res; 1994 Mar; 54(5):1205-11. PubMed ID: 8118807
    [TBL] [Abstract][Full Text] [Related]  

  • 19. O6-pyridyloxobutylguanine adducts contribute to the mutagenic properties of pyridyloxobutylating agents.
    Mijal RS; Loktionova NA; Vu CC; Pegg AE; Peterson LA
    Chem Res Toxicol; 2005 Oct; 18(10):1619-25. PubMed ID: 16533027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B; Cox JE; Upadhyaya P; Amin S; Desai D; Hoffmann D; el-Bayoumy K
    Carcinogenesis; 1996 Apr; 17(4):749-53. PubMed ID: 8625486
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.