207 related articles for article (PubMed ID: 19143565)
1. Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein kinases.
Lavogina D; Lust M; Viil I; König N; Raidaru G; Rogozina J; Enkvist E; Uri A; Bossemeyer D
J Med Chem; 2009 Jan; 52(2):308-21. PubMed ID: 19143565
[TBL] [Abstract][Full Text] [Related]
2. Effect of the structure of adenosine mimic of bisubstrate-analog inhibitors on their activity towards basophilic protein kinases.
Enkvist E; Kriisa M; Roben M; Kadak G; Raidaru G; Uri A
Bioorg Med Chem Lett; 2009 Nov; 19(21):6098-101. PubMed ID: 19800227
[TBL] [Abstract][Full Text] [Related]
3. NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: application to the catalytic subunit of cAMP-dependent protein kinase.
Langer T; Vogtherr M; Elshorst B; Betz M; Schieborr U; Saxena K; Schwalbe H
Chembiochem; 2004 Nov; 5(11):1508-16. PubMed ID: 15481030
[TBL] [Abstract][Full Text] [Related]
4. Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton.
Räägel H; Lust M; Uri A; Pooga M
FEBS J; 2008 Jul; 275(14):3608-24. PubMed ID: 18540886
[TBL] [Abstract][Full Text] [Related]
5. Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP.
Wu J; Jones JM; Nguyen-Huu X; Ten Eyck LF; Taylor SS
Biochemistry; 2004 Jun; 43(21):6620-9. PubMed ID: 15157095
[TBL] [Abstract][Full Text] [Related]
6. High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK.
Vaasa A; Viil I; Enkvist E; Viht K; Raidaru G; Lavogina D; Uri A
Anal Biochem; 2009 Feb; 385(1):85-93. PubMed ID: 19017524
[TBL] [Abstract][Full Text] [Related]
7. Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases.
Enkvist E; Lavogina D; Raidaru G; Vaasa A; Viil I; Lust M; Viht K; Uri A
J Med Chem; 2006 Nov; 49(24):7150-9. PubMed ID: 17125267
[TBL] [Abstract][Full Text] [Related]
8. Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP- and protein-competitive ligands of cAMP-dependent protein kinase.
Viht K; Schweinsberg S; Lust M; Vaasa A; Raidaru G; Lavogina D; Uri A; Herberg FW
Anal Biochem; 2007 Mar; 362(2):268-77. PubMed ID: 17274940
[TBL] [Abstract][Full Text] [Related]
9. PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
Kim C; Cheng CY; Saldanha SA; Taylor SS
Cell; 2007 Sep; 130(6):1032-43. PubMed ID: 17889648
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit.
Kriisa M; Sinijärv H; Vaasa A; Enkvist E; Kostenko S; Moens U; Uri A
Chembiochem; 2015 Jan; 16(2):312-9. PubMed ID: 25487811
[TBL] [Abstract][Full Text] [Related]
11. Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.
Simard JR; Getlik M; Grütter C; Pawar V; Wulfert S; Rabiller M; Rauh D
J Am Chem Soc; 2009 Sep; 131(37):13286-96. PubMed ID: 19572644
[TBL] [Abstract][Full Text] [Related]
12. Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool.
Åberg E; Lund B; Pflug A; Gani OA; Rothweiler U; de Oliveira TM; Engh RA
Biol Chem; 2012 Oct; 393(10):1121-9. PubMed ID: 23092797
[TBL] [Abstract][Full Text] [Related]
13. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA.
Kim C; Xuong NH; Taylor SS
Science; 2005 Feb; 307(5710):690-6. PubMed ID: 15692043
[TBL] [Abstract][Full Text] [Related]
14. Molecular basis of AKAP specificity for PKA regulatory subunits.
Gold MG; Lygren B; Dokurno P; Hoshi N; McConnachie G; Taskén K; Carlson CR; Scott JD; Barford D
Mol Cell; 2006 Nov; 24(3):383-95. PubMed ID: 17081989
[TBL] [Abstract][Full Text] [Related]
15. Cyclic-AMP and pseudosubstrate effects on type-I A-kinase regulatory and catalytic subunit binding kinetics.
Anand G; Taylor SS; Johnson DA
Biochemistry; 2007 Aug; 46(32):9283-91. PubMed ID: 17658893
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase.
Madhusudan ; Akamine P; Xuong NH; Taylor SS
Nat Struct Biol; 2002 Apr; 9(4):273-7. PubMed ID: 11896404
[TBL] [Abstract][Full Text] [Related]
17. Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants.
Breitenlechner CB; Friebe WG; Brunet E; Werner G; Graul K; Thomas U; Künkele KP; Schäfer W; Gassel M; Bossemeyer D; Huber R; Engh RA; Masjost B
J Med Chem; 2005 Jan; 48(1):163-70. PubMed ID: 15634010
[TBL] [Abstract][Full Text] [Related]
18. Computational proteomics of biomolecular interactions in the sequence and structure space of the tyrosine kinome: deciphering the molecular basis of the kinase inhibitors selectivity.
Verkhivker GM
Proteins; 2007 Mar; 66(4):912-29. PubMed ID: 17173284
[TBL] [Abstract][Full Text] [Related]
19. Carbocyclic 3'-deoxyadenosine-based highly potent bisubstrate-analog inhibitor of basophilic protein kinases.
Enkvist E; Raidaru G; Vaasa A; Pehk T; Lavogina D; Uri A
Bioorg Med Chem Lett; 2007 Oct; 17(19):5336-9. PubMed ID: 17716894
[TBL] [Abstract][Full Text] [Related]
20. Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: molecular yardsticks for analyzing catalytic mechanism and inhibitor design.
Hines AC; Parang K; Kohanski RA; Hubbard SR; Cole PA
Bioorg Chem; 2005 Aug; 33(4):285-97. PubMed ID: 16023488
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
