BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

463 related articles for article (PubMed ID: 19144697)

  • 1. Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.
    Tippmann F; Hundt J; Schneider A; Endres K; Fahrenholz F
    FASEB J; 2009 Jun; 23(6):1643-54. PubMed ID: 19144697
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
    Corbett GT; Gonzalez FJ; Pahan K
    Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8445-50. PubMed ID: 26080426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acitretin, an enhancer of alpha-secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein.
    Holthoewer D; Endres K; Schuck F; Hiemke C; Schmitt U; Fahrenholz F
    Neurodegener Dis; 2012; 10(1-4):224-8. PubMed ID: 22301853
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.
    Freese C; Reinhardt S; Hefner G; Unger RE; Kirkpatrick CJ; Endres K
    PLoS One; 2014; 9(3):e91003. PubMed ID: 24608847
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retinoids as a perspective in treatment of Alzheimer's disease.
    Fahrenholz F; Tippmann F; Endres K
    Neurodegener Dis; 2010; 7(1-3):190-2. PubMed ID: 20224284
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease.
    Reinhardt S; Schuck F; Grösgen S; Riemenschneider M; Hartmann T; Postina R; Grimm M; Endres K
    FASEB J; 2014 Feb; 28(2):978-97. PubMed ID: 24165480
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
    Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
    J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.
    Schroeder A; Fahrenholz F; Schmitt U
    J Alzheimers Dis; 2009; 16(2):309-14. PubMed ID: 19221420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Statins and the squalene synthase inhibitor zaragozic acid stimulate the non-amyloidogenic pathway of amyloid-beta protein precursor processing by suppression of cholesterol synthesis.
    Kojro E; Füger P; Prinzen C; Kanarek AM; Rat D; Endres K; Fahrenholz F; Postina R
    J Alzheimers Dis; 2010; 20(4):1215-31. PubMed ID: 20413873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress.
    Clement AB; Hanstein R; Schröder A; Nagel H; Endres K; Fahrenholz F; Behl C
    Neuroscience; 2008 Mar; 152(2):459-68. PubMed ID: 18276079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17.
    Shukla M; Htoo HH; Wintachai P; Hernandez JF; Dubois C; Postina R; Xu H; Checler F; Smith DR; Govitrapong P; Vincent B
    J Pineal Res; 2015 Mar; 58(2):151-65. PubMed ID: 25491598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stimulation of non-amyloidogenic processing of amyloid-β protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-α.
    Durairajan SS; Liu LF; Lu JH; Koo I; Maruyama K; Chung SK; Huang JD; Li M
    J Alzheimers Dis; 2011; 25(2):245-62. PubMed ID: 21403388
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.
    Donmez G; Wang D; Cohen DE; Guarente L
    Cell; 2010 Jul; 142(2):320-32. PubMed ID: 20655472
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rescue of Hypovitaminosis A Induces Non-Amyloidogenic Amyloid Precursor Protein (APP) Processing.
    Reinhardt S; Grimm MO; Stahlmann C; Hartmann T; Shudo K; Tomita T; Endres K
    Curr Alzheimer Res; 2016; 13(11):1277-1289. PubMed ID: 27335034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis.
    Hoe HS; Cooper MJ; Burns MP; Lewis PA; van der Brug M; Chakraborty G; Cartagena CM; Pak DT; Cookson MR; Rebeck GW
    J Neurosci; 2007 Oct; 27(40):10895-905. PubMed ID: 17913923
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.
    Lee HR; Shin HK; Park SY; Kim HY; Lee WS; Rhim BY; Hong KW; Kim CD
    J Neurosci Res; 2014 Nov; 92(11):1581-90. PubMed ID: 24903973
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cryptotanshinione upregulates alpha-secretase by activation PI3K pathway in cortical neurons.
    Mei Z; Situ B; Tan X; Zheng S; Zhang F; Yan P; Liu P
    Brain Res; 2010 Aug; 1348():165-73. PubMed ID: 20595051
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone deacetylase inhibitor apicidin increases expression of the α-secretase ADAM10 through transcription factor USF1-mediated mechanisms.
    Hu XT; Zhu BL; Zhao LG; Wang JW; Liu L; Lai YJ; He L; Deng XJ; Chen GJ
    FASEB J; 2017 Apr; 31(4):1482-1493. PubMed ID: 28003340
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice.
    Schmitt U; Hiemke C; Fahrenholz F; Schroeder A
    Behav Brain Res; 2006 Dec; 175(2):278-84. PubMed ID: 17014917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.