These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 19147571)

  • 1. gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
    Meng RD; Shelton CC; Li YM; Qin LX; Notterman D; Paty PB; Schwartz GK
    Cancer Res; 2009 Jan; 69(2):573-82. PubMed ID: 19147571
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.
    Timme CR; Gruidl M; Yeatman TJ
    Apoptosis; 2013 Oct; 18(10):1163-74. PubMed ID: 23887890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway.
    Zhang H; Ye Y; Bai Z; Wang S
    Dig Dis Sci; 2008 Aug; 53(8):2195-203. PubMed ID: 18320325
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pterostilbene exerts antitumor activity via the Notch1 signaling pathway in human lung adenocarcinoma cells.
    Yang Y; Yan X; Duan W; Yan J; Yi W; Liang Z; Wang N; Li Y; Chen W; Yu S; Jin Z; Yi D
    PLoS One; 2013; 8(5):e62652. PubMed ID: 23671619
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antiproliferative effects of γ-secretase inhibitor, a Notch signalling inhibitor, in multiple myeloma cells and its molecular mechanism of action.
    Hu J; Zhu X; Lu Q
    J Int Med Res; 2013 Aug; 41(4):1017-26. PubMed ID: 23839278
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Additive interaction of oxaliplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines results from inhibition of nuclear factor kappaB signaling.
    Rakitina TV; Vasilevskaya IA; O'Dwyer PJ
    Cancer Res; 2003 Dec; 63(24):8600-5. PubMed ID: 14695170
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death.
    Ametller E; García-Recio S; Pastor-Arroyo EM; Callejo G; Carbó N; Gascón P; Almendro V
    Cancer Biol Ther; 2011 Jan; 11(1):4-13. PubMed ID: 20980803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells.
    Ueno T; Endo S; Saito R; Hirose M; Hirai S; Suzuki H; Yamato K; Hyodo I
    Oncol Res; 2013; 21(3):155-64. PubMed ID: 24512730
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.
    Nemoto S; Nakamura M; Osawa Y; Kono S; Itoh Y; Okano Y; Murate T; Hara A; Ueda H; Nozawa Y; Banno Y
    J Biol Chem; 2009 Apr; 284(16):10422-32. PubMed ID: 19240026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780.
    Wang M; Wu L; Wang L; Xin X
    Biochem Biophys Res Commun; 2010 Feb; 393(1):144-9. PubMed ID: 20117093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
    Park JM; Huang S; Tougeron D; Sinicrope FA
    PLoS One; 2013; 8(5):e65369. PubMed ID: 23724141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.
    Koduru S; Kumar R; Srinivasan S; Evers MB; Damodaran C
    Mol Cancer Ther; 2010 Jan; 9(1):202-10. PubMed ID: 20053782
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells.
    Attoub S; Arafat K; Khalaf T; Sulaiman S; Iratni R
    Nutrients; 2018 May; 10(5):. PubMed ID: 29724012
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.
    Wei P; Walls M; Qiu M; Ding R; Denlinger RH; Wong A; Tsaparikos K; Jani JP; Hosea N; Sands M; Randolph S; Smeal T
    Mol Cancer Ther; 2010 Jun; 9(6):1618-28. PubMed ID: 20530712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Notch1 downregulation combined with interleukin-24 inhibits invasion and migration of hepatocellular carcinoma cells.
    Han B; Liu SH; Guo WD; Zhang B; Wang JP; Cao YK; Liu J
    World J Gastroenterol; 2015 Sep; 21(33):9727-35. PubMed ID: 26361419
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of gamma-secretase in Notch1 signaling pathway as a novel treatment for ovarian cancer.
    Feng Z; Xu W; Zhang C; Liu M; Wen H
    Oncotarget; 2017 Jan; 8(5):8215-8225. PubMed ID: 28030808
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin.
    Bommer UA; Vine KL; Puri P; Engel M; Belfiore L; Fildes K; Batterham M; Lochhead A; Aghmesheh M
    Cell Commun Signal; 2017 Feb; 15(1):9. PubMed ID: 28143584
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
    Tammam J; Ware C; Efferson C; O'Neil J; Rao S; Qu X; Gorenstein J; Angagaw M; Kim H; Kenific C; Kunii K; Leach KJ; Nikov G; Zhao J; Dai X; Hardwick J; Scott M; Winter C; Bristow L; Elbi C; Reilly JF; Look T; Draetta G; Van der Ploeg L; Kohl NE; Strack PR; Majumder PK
    Br J Pharmacol; 2009 Nov; 158(5):1183-95. PubMed ID: 19775282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel triazole, NMK-T-057, induces autophagic cell death in breast cancer cells by inhibiting γ-secretase-mediated activation of Notch signaling.
    Das A; Narayanam MK; Paul S; Mukhnerjee P; Ghosh S; Dastidar DG; Chakrabarty S; Ganguli A; Basu B; Pal M; Chatterji U; Banerjee SK; Karmakar P; Kumar D; Chakrabarti G
    J Biol Chem; 2019 Apr; 294(17):6733-6750. PubMed ID: 30824542
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.