253 related articles for article (PubMed ID: 19147752)
1. Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma.
Sun W; Zhou S; Chang SS; McFate T; Verma A; Califano JA
Clin Cancer Res; 2009 Jan; 15(2):476-84. PubMed ID: 19147752
[TBL] [Abstract][Full Text] [Related]
2. Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1α stabilization.
Sun W; Chang SS; Fu Y; Liu Y; Califano JA
PLoS One; 2011 Jan; 6(1):e16207. PubMed ID: 21283817
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1α/Mff regulation in head and neck squamous cell carcinoma.
Wu K; Mao YY; Chen Q; Zhang B; Zhang S; Wu HJ; Li Y
Cell Oncol (Dordr); 2021 Oct; 44(5):1167-1181. PubMed ID: 34460078
[TBL] [Abstract][Full Text] [Related]
4. TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Sun W; Liu Y; Glazer CA; Shao C; Bhan S; Demokan S; Zhao M; Rudek MA; Ha PK; Califano JA
Clin Cancer Res; 2010 Feb; 16(3):857-66. PubMed ID: 20103683
[TBL] [Abstract][Full Text] [Related]
5. Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
Zhou S; Kachhap S; Sun W; Wu G; Chuang A; Poeta L; Grumbine L; Mithani SK; Chatterjee A; Koch W; Westra WH; Maitra A; Glazer C; Carducci M; Sidransky D; McFate T; Verma A; Califano JA
Proc Natl Acad Sci U S A; 2007 May; 104(18):7540-5. PubMed ID: 17456604
[TBL] [Abstract][Full Text] [Related]
6. Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.
Roh JL; Park JY; Kim EH; Jang HJ; Kwon M
Cancer Lett; 2016 Feb; 371(1):20-9. PubMed ID: 26607904
[TBL] [Abstract][Full Text] [Related]
7. Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas.
Nakashima C; Kirita T; Yamamoto K; Mori S; Luo Y; Sasaki T; Fujii K; Ohmori H; Kawahara I; Mori T; Goto K; Kishi S; Fujiwara-Tani R; Kuniyasu H
Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998265
[TBL] [Abstract][Full Text] [Related]
8. Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer.
Sutendra G; Dromparis P; Kinnaird A; Stenson TH; Haromy A; Parker JM; McMurtry MS; Michelakis ED
Oncogene; 2013 Mar; 32(13):1638-50. PubMed ID: 22614004
[TBL] [Abstract][Full Text] [Related]
9. PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation.
Dunford EC; Herbst EA; Jeoung NH; Gittings W; Inglis JG; Vandenboom R; LeBlanc PJ; Harris RA; Peters SJ
Am J Physiol Regul Integr Comp Physiol; 2011 Jun; 300(6):R1487-93. PubMed ID: 21411764
[TBL] [Abstract][Full Text] [Related]
10. Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease.
Naia L; Cunha-Oliveira T; Rodrigues J; Rosenstock TR; Oliveira A; Ribeiro M; Carmo C; Oliveira-Sousa SI; Duarte AI; Hayden MR; Rego AC
J Neurosci; 2017 Mar; 37(10):2776-2794. PubMed ID: 28123081
[TBL] [Abstract][Full Text] [Related]
11. The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization.
Porcelli AM; Ghelli A; Ceccarelli C; Lang M; Cenacchi G; Capristo M; Pennisi LF; Morra I; Ciccarelli E; Melcarne A; Bartoletti-Stella A; Salfi N; Tallini G; Martinuzzi A; Carelli V; Attimonelli M; Rugolo M; Romeo G; Gasparre G
Hum Mol Genet; 2010 Mar; 19(6):1019-32. PubMed ID: 20028790
[TBL] [Abstract][Full Text] [Related]
12. Mutations and polymorphisms in mitochondrial DNA in head and neck cancer cell lines.
Allegra E; Garozzo A; Lombardo N; De Clemente M; Carey TE
Acta Otorhinolaryngol Ital; 2006 Aug; 26(4):185-90. PubMed ID: 18236634
[TBL] [Abstract][Full Text] [Related]
13. Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer.
Chen WH; Lecaros RL; Tseng YC; Huang L; Hsu YC
Cancer Lett; 2015 Apr; 359(1):65-74. PubMed ID: 25596376
[TBL] [Abstract][Full Text] [Related]
14. HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.
Prigione A; Rohwer N; Hoffmann S; Mlody B; Drews K; Bukowiecki R; Blümlein K; Wanker EE; Ralser M; Cramer T; Adjaye J
Stem Cells; 2014 Feb; 32(2):364-76. PubMed ID: 24123565
[TBL] [Abstract][Full Text] [Related]
15. Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic
Cenigaonandia-Campillo A; Serna-Blasco R; Gómez-Ocabo L; Solanes-Casado S; Baños-Herraiz N; Puerto-Nevado LD; Cañas JA; Aceñero MJ; García-Foncillas J; Aguilera Ó
Theranostics; 2021; 11(8):3595-3606. PubMed ID: 33664850
[No Abstract] [Full Text] [Related]
16. Mitochondrial outer membrane protein MTUS1/ATIP1 exerts antitumor effects through ROS-induced mitochondrial pyroptosis in head and neck squamous cell carcinoma.
Tang D; Zhao L; Huang S; Li W; He Q; Wang A
Int J Biol Sci; 2024; 20(7):2576-2591. PubMed ID: 38725862
[TBL] [Abstract][Full Text] [Related]
17. Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis.
Flora GD; Nayak MK; Ghatge M; Kumskova M; Patel RB; Chauhan AK
Blood Adv; 2023 Jun; 7(11):2347-2359. PubMed ID: 36971790
[TBL] [Abstract][Full Text] [Related]
18. A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.
Park JS; Sharma LK; Li H; Xiang R; Holstein D; Wu J; Lechleiter J; Naylor SL; Deng JJ; Lu J; Bai Y
Hum Mol Genet; 2009 May; 18(9):1578-89. PubMed ID: 19208652
[TBL] [Abstract][Full Text] [Related]
19. Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status.
Sandulache VC; Skinner HD; Ow TJ; Zhang A; Xia X; Luchak JM; Wong LJ; Pickering CR; Zhou G; Myers JN
Cancer; 2012 Feb; 118(3):711-21. PubMed ID: 21720999
[TBL] [Abstract][Full Text] [Related]
20. Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors.
Zhang M; Singh R; Peng S; Mazumdar T; Sambandam V; Shen L; Tong P; Li L; Kalu NN; Pickering CR; Frederick M; Myers JN; Wang J; Johnson FM
Cancer Lett; 2017 Apr; 392():71-82. PubMed ID: 28126323
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]