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4. Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm. Feng X; Sanchis J; Reetz MT; Rabitz H Chemistry; 2012 Apr; 18(18):5646-54. PubMed ID: 22434591 [TBL] [Abstract][Full Text] [Related]
5. Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods. Reetz MT; Prasad S; Carballeira JD; Gumulya Y; Bocola M J Am Chem Soc; 2010 Jul; 132(26):9144-52. PubMed ID: 20536132 [TBL] [Abstract][Full Text] [Related]
6. Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima. Gumulya Y; Sanchis J; Reetz MT Chembiochem; 2012 May; 13(7):1060-6. PubMed ID: 22522601 [TBL] [Abstract][Full Text] [Related]
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11. Enzyme engineering for enantioselectivity: from trial-and-error to rational design? Otten LG; Hollmann F; Arends IW Trends Biotechnol; 2010 Jan; 28(1):46-54. PubMed ID: 19913316 [TBL] [Abstract][Full Text] [Related]
12. Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions. Reetz MT; Wu S Chem Commun (Camb); 2008 Nov; (43):5499-501. PubMed ID: 18997931 [TBL] [Abstract][Full Text] [Related]
13. Natural history as a predictor of protein evolvability. O'Loughlin TL; Patrick WM; Matsumura I Protein Eng Des Sel; 2006 Oct; 19(10):439-42. PubMed ID: 16868005 [TBL] [Abstract][Full Text] [Related]
18. Directed evolution of a thermophilic beta-glucosidase for cellulosic bioethanol production. Hardiman E; Gibbs M; Reeves R; Bergquist P Appl Biochem Biotechnol; 2010 May; 161(1-8):301-12. PubMed ID: 19834652 [TBL] [Abstract][Full Text] [Related]
19. A statistical analysis of random mutagenesis methods used for directed protein evolution. Wong TS; Roccatano D; Zacharias M; Schwaneberg U J Mol Biol; 2006 Jan; 355(4):858-71. PubMed ID: 16325201 [TBL] [Abstract][Full Text] [Related]
20. Knowledge-guided laboratory evolution of protein thermolability. Reetz MT; Soni P; Fernández L Biotechnol Bioeng; 2009 Apr; 102(6):1712-7. PubMed ID: 19072845 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]