BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

412 related articles for article (PubMed ID: 19156407)

  • 1. Discovery of a pimaricin analog JBIR-13, from Streptomyces bicolor NBRC 12746 as predicted by sequence analysis of type I polyketide synthase gene.
    Komaki H; Izumikawa M; Ueda JY; Nakashima T; Khan ST; Takagi M; Shin-ya K
    Appl Microbiol Biotechnol; 2009 May; 83(1):127-33. PubMed ID: 19156407
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.
    Ward SL; Hu Z; Schirmer A; Reid R; Revill WP; Reeves CD; Petrakovsky OV; Dong SD; Katz L
    Antimicrob Agents Chemother; 2004 Dec; 48(12):4703-12. PubMed ID: 15561847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae.
    Pulsawat N; Kitani S; Nihira T
    Gene; 2007 May; 393(1-2):31-42. PubMed ID: 17350183
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Directed accumulation of less toxic pimaricin derivatives by improving the efficiency of a polyketide synthase dehydratase domain.
    Qi Z; Zhou Y; Kang Q; Jiang C; Zheng J; Bai L
    Appl Microbiol Biotechnol; 2017 Mar; 101(6):2427-2436. PubMed ID: 28054175
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.
    Yoo A; Demirev AV; Lee JS; Kim SD; Nam DH
    J Microbiol; 2006 Dec; 44(6):649-54. PubMed ID: 17205043
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.
    Xu Z; Jakobi K; Welzel K; Hertweck C
    Chem Biol; 2005 May; 12(5):579-88. PubMed ID: 15911378
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-colinear polyketide biosynthesis in the aureothin and neoaureothin pathways: an evolutionary perspective.
    Traitcheva N; Jenke-Kodama H; He J; Dittmann E; Hertweck C
    Chembiochem; 2007 Oct; 8(15):1841-9. PubMed ID: 17763486
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phylogenetic-affiliation, antimicrobial potential and PKS gene sequence analysis of moderately halophilic Streptomyces sp. inhabiting an Indian saltpan.
    Jose PA; Santhi VS; Jebakumar SR
    J Basic Microbiol; 2011 Aug; 51(4):348-56. PubMed ID: 21656796
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin.
    Wenzel SC; Bode HB; Kochems I; Müller R
    Chembiochem; 2008 Nov; 9(16):2711-21. PubMed ID: 18972512
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2).
    Pawlik K; Kotowska M; Chater KF; Kuczek K; Takano E
    Arch Microbiol; 2007 Feb; 187(2):87-99. PubMed ID: 17009021
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The hedamycin locus implicates a novel aromatic PKS priming mechanism.
    Bililign T; Hyun CG; Williams JS; Czisny AM; Thorson JS
    Chem Biol; 2004 Jul; 11(7):959-69. PubMed ID: 15271354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Polyketide antibiotics produced by polyketide synthase in streptomyces--a review].
    Chen M; Wang G; Dai S; Xie L; Li X
    Wei Sheng Wu Xue Bao; 2009 Dec; 49(12):1555-63. PubMed ID: 20222438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The methoxymalonyl-acyl carrier protein biosynthesis locus and the nearby gene with the beta-ketoacyl synthase domain are involved in the biosynthesis of galbonolides in Streptomyces galbus, but these loci are separate from the modular polyketide synthase gene cluster.
    Karki S; Kwon SY; Yoo HG; Suh JW; Park SH; Kwon HJ
    FEMS Microbiol Lett; 2010 Sep; 310(1):69-75. PubMed ID: 20662933
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.
    Aparicio JF; Fouces R; Mendes MV; Olivera N; Martín JF
    Chem Biol; 2000 Nov; 7(11):895-905. PubMed ID: 11094342
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isolation and characterization of pcsB, the gene for a polyene carboxamide synthase that tailors pimaricin into AB-400.
    Miranzo D; Seco EM; Cuesta T; Malpartida F
    Appl Microbiol Biotechnol; 2010 Feb; 85(6):1809-19. PubMed ID: 19707754
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts.
    Reeves CD; Ward SL; Revill WP; Suzuki H; Marcus M; Petrakovsky OV; Marquez S; Fu H; Dong SD; Katz L
    Chem Biol; 2004 Oct; 11(10):1465-72. PubMed ID: 15489173
    [TBL] [Abstract][Full Text] [Related]  

  • 17. From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes.
    Frank B; Wenzel SC; Bode HB; Scharfe M; Blöcker H; Müller R
    J Mol Biol; 2007 Nov; 374(1):24-38. PubMed ID: 17919655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the polyene macrolide P450 epoxidase from Streptomyces natalensis that converts de-epoxypimaricin into pimaricin.
    Mendes MV; Antón N; Martín JF; Aparicio JF
    Biochem J; 2005 Feb; 386(Pt 1):57-62. PubMed ID: 15228385
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cholesterol oxidases act as signaling proteins for the biosynthesis of the polyene macrolide pimaricin.
    Mendes MV; Recio E; Antón N; Guerra SM; Santos-Aberturas J; Martín JF; Aparicio JF
    Chem Biol; 2007 Mar; 14(3):279-90. PubMed ID: 17379143
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997.
    Li YH; Li M; He WQ; Wang YG; Shao RG
    Genet Mol Res; 2013 Jun; 12(2):2076-85. PubMed ID: 23913387
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.