BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 19158955)

  • 1. The internally truncated LRP5 receptor presents a therapeutic target in breast cancer.
    Björklund P; Svedlund J; Olsson AK; Akerström G; Westin G
    PLoS One; 2009; 4(1):e4243. PubMed ID: 19158955
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling.
    Björklund P; Akerström G; Westin G
    PLoS Med; 2007 Nov; 4(11):e328. PubMed ID: 18044981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies.
    Ettenberg SA; Charlat O; Daley MP; Liu S; Vincent KJ; Stuart DD; Schuller AG; Yuan J; Ospina B; Green J; Yu Q; Walsh R; Li S; Schmitz R; Heine H; Bilic S; Ostrom L; Mosher R; Hartlepp KF; Zhu Z; Fawell S; Yao YM; Stover D; Finan PM; Porter JA; Sellers WR; Klagge IM; Cong F
    Proc Natl Acad Sci U S A; 2010 Aug; 107(35):15473-8. PubMed ID: 20713706
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.
    Haÿ E; Laplantine E; Geoffroy V; Frain M; Kohler T; Müller R; Marie PJ
    Mol Cell Biol; 2009 Feb; 29(4):953-64. PubMed ID: 19075000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Redundant expression of canonical Wnt ligands in human breast cancer cell lines.
    Benhaj K; Akcali KC; Ozturk M
    Oncol Rep; 2006 Mar; 15(3):701-7. PubMed ID: 16465433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases.
    Bu G; Lu W; Liu CC; Selander K; Yoneda T; Hall C; Keller ET; Li Y
    Int J Cancer; 2008 Sep; 123(5):1034-42. PubMed ID: 18546262
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and β-catenin.
    Wo D; Peng J; Ren DN; Qiu L; Chen J; Zhu Y; Yan Y; Yan H; Wu J; Ma E; Zhong TP; Chen Y; Liu Z; Liu S; Ao L; Liu Z; Jiang C; Peng J; Zou Y; Qian Q; Zhu W
    Circulation; 2016 Dec; 134(24):1991-2007. PubMed ID: 27803037
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.
    Qiang YW; Barlogie B; Rudikoff S; Shaughnessy JD
    Bone; 2008 Apr; 42(4):669-80. PubMed ID: 18294945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation.
    Swiatek W; Kang H; Garcia BA; Shabanowitz J; Coombs GS; Hunt DF; Virshup DM
    J Biol Chem; 2006 May; 281(18):12233-41. PubMed ID: 16513652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.
    Hay E; Faucheu C; Suc-Royer I; Touitou R; Stiot V; Vayssière B; Baron R; Roman-Roman S; Rawadi G
    J Biol Chem; 2005 Apr; 280(14):13616-23. PubMed ID: 15699046
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop.
    Rawadi G; Vayssière B; Dunn F; Baron R; Roman-Roman S
    J Bone Miner Res; 2003 Oct; 18(10):1842-53. PubMed ID: 14584895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism.
    Endo Y; Beauchamp E; Woods D; Taylor WG; Toretsky JA; Uren A; Rubin JS
    Mol Cell Biol; 2008 Apr; 28(7):2368-79. PubMed ID: 18212053
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway.
    Hua Y; Yang Y; Li Q; He X; Zhu W; Wang J; Gan X
    J Biol Chem; 2018 Dec; 293(51):19710-19724. PubMed ID: 30361437
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.
    Bryja V; Andersson ER; Schambony A; Esner M; Bryjová L; Biris KK; Hall AC; Kraft B; Cajanek L; Yamaguchi TP; Buckingham M; Arenas E
    Mol Biol Cell; 2009 Feb; 20(3):924-36. PubMed ID: 19056682
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.
    Liu CC; Prior J; Piwnica-Worms D; Bu G
    Proc Natl Acad Sci U S A; 2010 Mar; 107(11):5136-41. PubMed ID: 20194742
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling.
    Yamamoto H; Sakane H; Yamamoto H; Michiue T; Kikuchi A
    Dev Cell; 2008 Jul; 15(1):37-48. PubMed ID: 18606139
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p38 MAP kinase is required for Wnt3a-mediated osterix expression independently of Wnt-LRP5/6-GSK3β signaling axis in dental follicle cells.
    Sakisaka Y; Kanaya S; Nakamura T; Tamura M; Shimauchi H; Nemoto E
    Biochem Biophys Res Commun; 2016 Sep; 478(2):527-32. PubMed ID: 27450807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization.
    Chen Y; Hu Y; Lu K; Flannery JG; Ma JX
    J Biol Chem; 2007 Nov; 282(47):34420-8. PubMed ID: 17890782
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development.
    Lindvall C; Zylstra CR; Evans N; West RA; Dykema K; Furge KA; Williams BO
    PLoS One; 2009 Jun; 4(6):e5813. PubMed ID: 19503830
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.
    Almeida M; Han L; Bellido T; Manolagas SC; Kousteni S
    J Biol Chem; 2005 Dec; 280(50):41342-51. PubMed ID: 16251184
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.