BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 19162045)

  • 1. The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.
    Birtwistle J; Hayden RE; Khanim FL; Green RM; Pearce C; Davies NJ; Wake N; Schrewe H; Ride JP; Chipman JK; Bunce CM
    Mutat Res; 2009 Mar; 662(1-2):67-74. PubMed ID: 19162045
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.
    Desmond JC; Mountford JC; Drayson MT; Walker EA; Hewison M; Ride JP; Luong QT; Hayden RE; Vanin EF; Bunce CM
    Cancer Res; 2003 Jan; 63(2):505-12. PubMed ID: 12543809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The bioreductive prodrug PR-104A is activated under aerobic conditions by human aldo-keto reductase 1C3.
    Guise CP; Abbattista MR; Singleton RS; Holford SD; Connolly J; Dachs GU; Fox SB; Pollock R; Harvey J; Guilford P; Doñate F; Wilson WR; Patterson AV
    Cancer Res; 2010 Feb; 70(4):1573-84. PubMed ID: 20145130
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma.
    Fung KM; Samara EN; Wong C; Metwalli A; Krlin R; Bane B; Liu CZ; Yang JT; Pitha JV; Culkin DJ; Kropp BP; Penning TM; Lin HK
    Endocr Relat Cancer; 2006 Mar; 13(1):169-80. PubMed ID: 16601286
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitors.
    Penning TM; Steckelbroeck S; Bauman DR; Miller MW; Jin Y; Peehl DM; Fung KM; Lin HK
    Mol Cell Endocrinol; 2006 Mar; 248(1-2):182-91. PubMed ID: 16417966
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of aldo-keto reductase 1C3 (AKR1C3)-mediated prostaglandin D2 (PGD2) metabolism in keloids.
    Mantel A; Newsome A; Thekkudan T; Frazier R; Katdare M
    Exp Dermatol; 2016 Jan; 25(1):38-43. PubMed ID: 26308156
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells.
    Matsunaga T; Arakaki M; Kamiya T; Endo S; El-Kabbani O; Hara A
    Chem Biol Interact; 2009 Sep; 181(1):52-60. PubMed ID: 19442656
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aldo-keto reductase 1C3 may be a new radioresistance marker in non-small-cell lung cancer.
    Xie L; Yu J; Guo W; Wei L; Liu Y; Wang X; Song X
    Cancer Gene Ther; 2013 Apr; 20(4):260-6. PubMed ID: 23519145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism.
    Mantel A; Carpenter-Mendini A; VanBuskirk J; Pentland AP
    Exp Dermatol; 2014 Aug; 23(8):573-8. PubMed ID: 24917395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toxic effects of methylated benz[a]anthracenes in liver cells.
    Marvanová S; Vondrácek J; Penccíková K; Trilecová L; Krcmárr P; Topinka J; Nováková Z; Milcová A; Machala M
    Chem Res Toxicol; 2008 Feb; 21(2):503-12. PubMed ID: 18205319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Paracrine-stimulated gene expression profile favors estradiol production in breast tumors.
    Amin SA; Huang CC; Reierstad S; Lin Z; Arbieva Z; Wiley E; Saborian H; Haynes B; Cotterill H; Dowsett M; Bulun SE
    Mol Cell Endocrinol; 2006 Jul; 253(1-2):44-55. PubMed ID: 16735089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.
    Palackal NT; Lee SH; Harvey RG; Blair IA; Penning TM
    J Biol Chem; 2002 Jul; 277(27):24799-808. PubMed ID: 11978787
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anthracycline resistance mediated by reductive metabolism in cancer cells: the role of aldo-keto reductase 1C3.
    Hofman J; Malcekova B; Skarka A; Novotna E; Wsol V
    Toxicol Appl Pharmacol; 2014 Aug; 278(3):238-48. PubMed ID: 24832494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevated expression of AKR1C3 increases resistance of cancer cells to ionizing radiation via modulation of oxidative stress.
    Xiong W; Zhao J; Yu H; Li X; Sun S; Li Y; Xia Q; Zhang C; He Q; Gao X; Zhang L; Zhou D
    PLoS One; 2014; 9(11):e111911. PubMed ID: 25419901
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells.
    Doig CL; Battaglia S; Khanim FL; Bunce CM; Campbell MJ
    J Steroid Biochem Mol Biol; 2016 Jan; 155(Pt A):47-55. PubMed ID: 26429394
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.
    Ruiz FX; Porté S; Gallego O; Moro A; Ardèvol A; Del Río-Espínola A; Rovira C; Farrés J; Parés X
    Biochem J; 2011 Dec; 440(3):335-44. PubMed ID: 21851338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.
    Marín YE; Seiberg M; Lin CB
    Exp Dermatol; 2009 Jul; 18(7):611-8. PubMed ID: 19320734
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells.
    Wang S; Yang Q; Fung KM; Lin HK
    Mol Cell Endocrinol; 2008 Jul; 289(1-2):60-6. PubMed ID: 18508192
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTHrP stimulates prostate cancer cell growth and upregulates aldo-keto reductase 1C3.
    Downs TM; Burton DW; Araiza FL; Hastings RH; Deftos LJ
    Cancer Lett; 2011 Jul; 306(1):52-9. PubMed ID: 21444150
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate.
    Lin HK; Steckelbroeck S; Fung KM; Jones AN; Penning TM
    Steroids; 2004 Dec; 69(13-14):795-801. PubMed ID: 15582534
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.