BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

388 related articles for article (PubMed ID: 19162173)

  • 1. Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species.
    Ren H; Vallanat B; Nelson DM; Yeung LWY; Guruge KS; Lam PKS; Lehman-McKeeman LD; Corton JC
    Reprod Toxicol; 2009 Jun; 27(3-4):266-277. PubMed ID: 19162173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.
    Rosen MB; Lee JS; Ren H; Vallanat B; Liu J; Waalkes MP; Abbott BD; Lau C; Corton JC
    Toxicol Sci; 2008 May; 103(1):46-56. PubMed ID: 18281256
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.
    Rosen MB; Das KP; Rooney J; Abbott B; Lau C; Corton JC
    Toxicology; 2017 Jul; 387():95-107. PubMed ID: 28558994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR.
    Elcombe CR; Elcombe BM; Foster JR; Chang SC; Ehresman DJ; Butenhoff JL
    Toxicology; 2012 Mar; 293(1-3):16-29. PubMed ID: 22245121
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcription of genes involved in fat metabolism in chicken embryos exposed to the peroxisome proliferator-activated receptor alpha (PPARα) agonist GW7647 or to perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA).
    Strömqvist M; Olsson JA; Kärrman A; Brunström B
    Comp Biochem Physiol C Toxicol Pharmacol; 2012 Jun; 156(1):29-36. PubMed ID: 22465071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X; Klaassen CD
    Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
    Luisier R; Lempiäinen H; Scherbichler N; Braeuning A; Geissler M; Dubost V; Müller A; Scheer N; Chibout SD; Hara H; Picard F; Theil D; Couttet P; Vitobello A; Grenet O; Grasl-Kraupp B; Ellinger-Ziegelbauer H; Thomson JP; Meehan RR; Elcombe CR; Henderson CJ; Wolf CR; Schwarz M; Moulin P; Terranova R; Moggs JG
    Toxicol Sci; 2014 Jun; 139(2):501-11. PubMed ID: 24690595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate.
    Takacs ML; Abbott BD
    Toxicol Sci; 2007 Jan; 95(1):108-17. PubMed ID: 17047030
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Ren H; Aleksunes LM; Wood C; Vallanat B; George MH; Klaassen CD; Corton JC
    Toxicol Sci; 2010 Jan; 113(1):45-59. PubMed ID: 19850644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: comparison to changes induced by exposure to perfluorooctanoic acid.
    Rosen MB; Schmid JE; Das KP; Wood CR; Zehr RD; Lau C
    Reprod Toxicol; 2009 Jun; 27(3-4):278-288. PubMed ID: 19429403
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis.
    Das KP; Wood CR; Lin MT; Starkov AA; Lau C; Wallace KB; Corton JC; Abbott BD
    Toxicology; 2017 Mar; 378():37-52. PubMed ID: 28049043
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S; Billy LJ; Chang S; Gonzalez FJ; Patterson AD; Peters JM
    Toxicology; 2022 Jan; 465():153056. PubMed ID: 34861291
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes.
    Bjork JA; Butenhoff JL; Wallace KB
    Toxicology; 2011 Oct; 288(1-3):8-17. PubMed ID: 21723365
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
    Cui JY; Klaassen CD
    Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium.
    Oshida K; Vasani N; Jones C; Moore T; Hester S; Nesnow S; Auerbach S; Geter DR; Aleksunes LM; Thomas RS; Applegate D; Klaassen CD; Corton JC
    Nucl Recept Signal; 2015; 13():e002. PubMed ID: 25949234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.
    Abe T; Takahashi M; Kano M; Amaike Y; Ishii C; Maeda K; Kudoh Y; Morishita T; Hosaka T; Sasaki T; Kodama S; Matsuzawa A; Kojima H; Yoshinari K
    Arch Toxicol; 2017 Jun; 91(6):2365-2374. PubMed ID: 27832320
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.
    Cheng X; Klaassen CD
    Toxicol Sci; 2008 Nov; 106(1):37-45. PubMed ID: 18703564
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
    Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPAR alpha) in the mouse.
    Abbott BD; Wolf CJ; Das KP; Zehr RD; Schmid JE; Lindstrom AB; Strynar MJ; Lau C
    Reprod Toxicol; 2009 Jun; 27(3-4):258-265. PubMed ID: 18595657
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.