BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 19172738)

  • 1. Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.
    Brummer T; Larance M; Herrera Abreu MT; Lyons RJ; Timpson P; Emmerich CH; Fleuren ED; Lehrbach GM; Schramek D; Guilhaus M; James DE; Daly RJ
    EMBO J; 2008 Sep; 27(17):2305-16. PubMed ID: 19172738
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases.
    Lock LS; Royal I; Naujokas MA; Park M
    J Biol Chem; 2000 Oct; 275(40):31536-45. PubMed ID: 10913131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.
    Lynch DK; Daly RJ
    EMBO J; 2002 Jan; 21(1-2):72-82. PubMed ID: 11782427
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation.
    Arnaud M; Crouin C; Deon C; Loyaux D; Bertoglio J
    J Immunol; 2004 Sep; 173(6):3962-71. PubMed ID: 15356145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.
    Zhang X; Lavoie G; Méant A; Aubert L; Cargnello M; Haman A; Hoang T; Roux PP
    Mol Cell Biol; 2017 Apr; 37(7):. PubMed ID: 28096188
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells.
    Yamasaki S; Nishida K; Sakuma M; Berry D; McGlade CJ; Hirano T; Saito T
    Mol Cell Biol; 2003 Apr; 23(7):2515-29. PubMed ID: 12640133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V; Scott RP; Ibáñez CF
    J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.
    Zhang X; Lavoie G; Fort L; Huttlin EL; Tcherkezian J; Galan JA; Gu H; Gygi SP; Carreno S; Roux PP
    Mol Cell Biol; 2013 Apr; 33(8):1657-70. PubMed ID: 23401857
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
    Nyga R; Pecquet C; Harir N; Gu H; Dhennin-Duthille I; Régnier A; Gouilleux-Gruart V; Lassoued K; Gouilleux F
    Biochem J; 2005 Aug; 390(Pt 1):359-66. PubMed ID: 15833084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. G-CSF-induced tyrosine phosphorylation of Gab2 is Lyn kinase dependent and associated with enhanced Akt and differentiative, not proliferative, responses.
    Zhu QS; Robinson LJ; Roginskaya V; Corey SJ
    Blood; 2004 May; 103(9):3305-12. PubMed ID: 14656892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epidermal growth factor-induced DNA synthesis. Key role for Src phosphorylation of the docking protein Gab2.
    Kong M; Mounier C; Dumas V; Posner BI
    J Biol Chem; 2003 Feb; 278(8):5837-44. PubMed ID: 12464621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1.
    Zhao C; Yu DH; Shen R; Feng GS
    J Biol Chem; 1999 Jul; 274(28):19649-54. PubMed ID: 10391903
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of the Gab2 scaffolding adapter in type I interferon signalling.
    Baychelier F; Nardeux PC; Cajean-Feroldi C; Ermonval M; Guymarho J; Tovey MG; Eid P
    Cell Signal; 2007 Oct; 19(10):2080-7. PubMed ID: 17604604
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.
    Lock LS; Maroun CR; Naujokas MA; Park M
    Mol Biol Cell; 2002 Jun; 13(6):2132-46. PubMed ID: 12058075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor.
    Meng S; Chen Z; Munoz-Antonia T; Wu J
    Biochem J; 2005 Oct; 391(Pt 1):143-51. PubMed ID: 15952937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
    Yamasaki S; Nishida K; Hibi M; Sakuma M; Shiina R; Takeuchi A; Ohnishi H; Hirano T; Saito T
    J Biol Chem; 2001 Nov; 276(48):45175-83. PubMed ID: 11572860
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gab2 tyrosine phosphorylation by a pleckstrin homology domain-independent mechanism: role in epidermal growth factor-induced mitogenesis.
    Kong M; Mounier C; Balbis A; Baquiran G; Posner BI
    Mol Endocrinol; 2003 May; 17(5):935-44. PubMed ID: 12595575
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells.
    Caron C; Spring K; Laramée M; Chabot C; Cloutier M; Gu H; Royal I
    Cell Signal; 2009 Jun; 21(6):943-53. PubMed ID: 19233262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor.
    Frigault MM; Naujokas MA; Park M
    J Cell Physiol; 2008 Mar; 214(3):694-705. PubMed ID: 17894413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies.
    Simister PC; Feller SM
    Mol Biosyst; 2012 Jan; 8(1):33-46. PubMed ID: 21935523
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.