These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 19176818)

  • 1. The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord.
    Codeluppi S; Svensson CI; Hefferan MP; Valencia F; Silldorff MD; Oshiro M; Marsala M; Pasquale EB
    J Neurosci; 2009 Jan; 29(4):1093-104. PubMed ID: 19176818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
    Alam H; Maizels ET; Park Y; Ghaey S; Feiger ZJ; Chandel NS; Hunzicker-Dunn M
    J Biol Chem; 2004 May; 279(19):19431-40. PubMed ID: 14982927
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin mediates mTOR signaling in reactive astrocytes and reduces retinal ganglion cell loss.
    Li N; Wang F; Zhang Q; Jin M; Lu Y; Chen S; Guo C; Zhang X
    Exp Eye Res; 2018 Nov; 176():10-19. PubMed ID: 29928901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.
    Uhlmann EJ; Li W; Scheidenhelm DK; Gau CL; Tamanoi F; Gutmann DH
    Glia; 2004 Aug; 47(2):180-8. PubMed ID: 15185396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
    Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
    J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner.
    Banerjee S; Crouse NR; Emnett RJ; Gianino SM; Gutmann DH
    Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15996-6001. PubMed ID: 21896734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the Rheb-mTOR signaling pathway in mammalian cells: constitutive active mutants of Rheb and mTOR.
    Sato T; Umetsu A; Tamanoi F
    Methods Enzymol; 2008; 438():307-20. PubMed ID: 18413257
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MiR-17 targets PTEN and facilitates glial scar formation after spinal cord injuries via the PI3K/Akt/mTOR pathway.
    Luan Y; Chen M; Zhou L
    Brain Res Bull; 2017 Jan; 128():68-75. PubMed ID: 27693649
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of the PI3K/Akt/mTOR pathway in glial scar formation following spinal cord injury.
    Chen CH; Sung CS; Huang SY; Feng CW; Hung HC; Yang SN; Chen NF; Tai MH; Wen ZH; Chen WF
    Exp Neurol; 2016 Apr; 278():27-41. PubMed ID: 26828688
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar.
    Wu D; Klaw MC; Connors T; Kholodilov N; Burke RE; Tom VJ
    J Neurosci; 2015 Aug; 35(31):11068-80. PubMed ID: 26245968
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity.
    Basso AD; Mirza A; Liu G; Long BJ; Bishop WR; Kirschmeier P
    J Biol Chem; 2005 Sep; 280(35):31101-8. PubMed ID: 16006564
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury.
    Li ZW; Li JJ; Wang L; Zhang JP; Wu JJ; Mao XQ; Shi GF; Wang Q; Wang F; Zou J
    J Neuroinflammation; 2014 Apr; 11():71. PubMed ID: 24708754
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phospholipase D1 is an effector of Rheb in the mTOR pathway.
    Sun Y; Fang Y; Yoon MS; Zhang C; Roccio M; Zwartkruis FJ; Armstrong M; Brown HA; Chen J
    Proc Natl Acad Sci U S A; 2008 Jun; 105(24):8286-91. PubMed ID: 18550814
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
    Mavrakis KJ; Zhu H; Silva RL; Mills JR; Teruya-Feldstein J; Lowe SW; Tam W; Pelletier J; Wendel HG
    Genes Dev; 2008 Aug; 22(16):2178-88. PubMed ID: 18708578
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuregulin-1 converts reactive astrocytes toward oligodendrocyte lineage cells via upregulating the PI3K-AKT-mTOR pathway to repair spinal cord injury.
    Ding Z; Dai C; Zhong L; Liu R; Gao W; Zhang H; Yin Z
    Biomed Pharmacother; 2021 Feb; 134():111168. PubMed ID: 33395598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rheb, an activator of target of rapamycin, in the blackback land crab, Gecarcinus lateralis: cloning and effects of molting and unweighting on expression in skeletal muscle.
    MacLea KS; Abuhagr AM; Pitts NL; Covi JA; Bader BD; Chang ES; Mykles DL
    J Exp Biol; 2012 Feb; 215(Pt 4):590-604. PubMed ID: 22279066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ras homolog enriched in brain (Rheb) enhances apoptotic signaling.
    Karassek S; Berghaus C; Schwarten M; Goemans CG; Ohse N; Kock G; Jockers K; Neumann S; Gottfried S; Herrmann C; Heumann R; Stoll R
    J Biol Chem; 2010 Oct; 285(44):33979-91. PubMed ID: 20685651
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transforming growth factor α transforms astrocytes to a growth-supportive phenotype after spinal cord injury.
    White RE; Rao M; Gensel JC; McTigue DM; Kaspar BK; Jakeman LB
    J Neurosci; 2011 Oct; 31(42):15173-87. PubMed ID: 22016551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rheb binds and regulates the mTOR kinase.
    Long X; Lin Y; Ortiz-Vega S; Yonezawa K; Avruch J
    Curr Biol; 2005 Apr; 15(8):702-13. PubMed ID: 15854902
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
    Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
    Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.